Protein
2-dehydro-3-deoxy-L-rhamnonate dehydrogenase (NAD(+))
Organism
Sulfobacillus thermosulfidooxidans (strain DSM 9293 / VKM B-1269 / AT-1)
Function
Catalyzes the NAD(+)-dependent dehydrogenation of 2-dehydro-3-deoxy-L-rhamnonate to 2,4-didehydro-3-deoxy-L-rhamnonate. Also has weak dehydrogenase activity on butane-2,3-diol. Does not show any detectable activity in the presence of NADP(+).
Similarity
Belongs to the zinc-containing alcohol dehydrogenase family.
Sequence
MKTLTWTAKETMSILSAPAPVPEPGWIALRVAGVGICGSELSGYLGHNELRKPPLVMGHEFSGVVEEVGHGVTNVKIGDLVTANPLVTCGRCIHCLRGERQRCESRRIIGIDFPGAYAERVLVPSNQCYAVKDAIDGALVEPLACAVRAVGLARIKVGDTAVVIGAGIIGLMTVRLLGLSGAKRIAVVDPNDERLKISQLWGATEMAPNLGALLTDNHPQSFDCVIDAVGLSTTRRDSLNALIRGGRAVWIGLHEALTHLDGNQIVRDELEVRGSFCYTDDEFIRAVSLINSQKFLPVDRQWLDVRSLEEGPAAFKELVNGSPFSKIILTF