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Sult1c1

Gene
Sult1c1
Protein
Sulfotransferase 1C1
Organism
Mus musculus
Length
304 amino acids
Function
Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the sulfate conjugation of drugs, xenobiotic compounds, hormones, and neurotransmitters. May be involved in the activation of carcinogenic hydroxylamines. Shows activity towards p-nitrophenol and N-hydroxy-2-acetylamino-fluorene (N-OH-2AAF). Also shows activity towards cinnamyl alcohol at pH 6.4 but not at pH 5.5, and towards a number of phenolic odorants including eugenol, guaiacol and 2-naphthol.
Similarity
Belongs to the sulfotransferase 1 family.
Mass
35.797 kDa
Sequence
MPLEKLKDLHLDEQNMQPETREVNGILMSKMMSENWDKIWNFQAKPDDLLIATYAKAGTTWTQEIVDMIQNDGDVQKCQRANTYDRHPFIEWTLPPPLNSGLDLANKMPSPRTLKTHLPVQMLPPSFWKENSKIIYVARNAKDCLVSYYYFSRMNKMLPDPGTLGEYIETFKAGKVLWGSWYDHVKGWWDVKDKHRILYLFYEDMKEDPKREIKKIVKFLEKDISEEVLNKIIHHTSFDVMKQNPMANYTTLPSSIMDHSISPFMRKGMPGDWKNYFTVAQSEDFDEDYRKKMAGSTITFRTEI

Gene
Sult1c1
Protein
Sulfotransferase 1C1
Organism
Rattus norvegicus
Length
304 amino acids
Function
Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the sulfate conjugation of drugs, xenobiotic compounds, hormones, and neurotransmitters. May be involved in the activation of carcinogenic hydroxylamines (By similarity).
Similarity
Belongs to the sulfotransferase 1 family.
Mass
35.764 kDa
Sequence
MSLEKMKDLHLGEQDLQPETREVNGILMSKLMSDNWDKIWNFQAKPDDLLIATYAKAGTTWTQEIVDMIQNDGDVQKCQRANTYDRHPFIEWTLPSPLNSGLDLANKMPSPRTLKTHLPVHMLPPSFWKENSKIIYVARNAKDCLVSYYYFSRMNKMLPDPGTLGEYIEQFKAGKVLWGSWYDHVKGWWDVKDQHRILYLFYEDMKEDPKREIKKIAKFLEKDISEEVLNKIIYHTSFDVMKENPMANYTTLPSSIMDHSISPFMRKGMPGDWKNYFTVAQSEDFDEDYRRKMAGSNITFRTEI