Organism
Shewanella pealeana (strain ATCC 700345 / ANG-SQ1)
Function
In vitro, catalyzes the dehydration of trans-3-hydroxy-L-proline (t3LHyp) to Delta(1)-pyrroline-2-carboxylate (Pyr2C), albeit with very low efficiency. The physiological substrate may be different. Displays neither trans-4-hydroxy-L-proline (t4LHyp) epimerase nor proline racemase activity.
Similarity
Belongs to the proline racemase family.
Sequence
MQSITITPDLSSNFKDFVTIDAHTEGEPLRVIISGYPEIKGSTILEKRQYVQQNLDTYRKLLMHEPRGHADMYGALITEAVTEEADFGVLFLHNEGYSSMCGHGILALVKVMCQTDSIDLGLEPRTIKIDSPAGLITAKAYRDSQGKIQASFKNVDSWADALNCSVNVEGFGEVNYDIGFGGAYYAYVDADEHGISCGQDNVAQLIDVGRRIKHAVMASHTLVHPLEEDLSFLYGTIFTSKKVTNPEAHSRHVCIFADGEVDRSPTGTGVSARVALLYAKGEVALNTPIMIESIVDGRMIVSASAESEFHGKQGVIPEVSGRSFITGKHQFFIDPDDVFQNGFMLR