Organism
Drosophila melanogaster
Function
Seminal fluid protease which is required for cleavage and probably also activation of the metalloprotease Semp1 (PubMed:22253601, PubMed:24514904). Also required for a number of female post-mating responses independent of Semp1 including egg laying and sperm usage (PubMed:22253601).
Similarity
Belongs to the peptidase S1 family.
Sequence
MKRLLFLFLLAGILINNHALQHNETIDLKKLAKIVLPPAYQTRVIGGRVTTNAKLGGYLVAMRYFNNFICGGTLIHELIVLTAAHCFEDRAEKEAWSVDGGISRLSEKGIRRQVKRFIKSAQFKMVTMNMDVAVVLLNRPMVGKNIGTLSLCSTALTPGQTMDVSGWGMTNPDDEGPGHMLRTVSVPVIEKRICREAYRESVSISDSMFCASVLGKKDACTYDSGGPLVYEKQVCGIVSFGIGCASRRYPGVYTDVHYVKPFIVKGIKALLSRSR