SUSD2

Gene

SUSD2

Protein

Sushi domain-containing protein 2

Organism

Homo sapiens

Length

822 amino acids

Function

May be a cytokine receptor for C10ORF99. May be a tumor suppressor; together with C10ORF99 has a growth inhibitory effect on colon cancer cells which includes G1 cell cycle arrest (PubMed:25351403). May play a role in breast tumorigenesis (PubMed:23131994).

Mass

90.208 kDa

Sequence

MKPALLPWALLLLATALGPGPGPTADAQESCSMRCGALDGPCSCHPTCSGLGTCCLDFRDFCLEILPYSGSMMGGKDFVVRHFKMSSPTDASVICRFKDSIQTLGHVDSSGQVHCVSPLLYESGRIPFTVSLDNGHSFPRAGTWLAVHPNKVSMMEKSELVNETRWQYYGTANTSGNLSLTWHVKSLPTQTITIELWGYEETGMPYSQEWTAKWSYLYPLATHIPNSGSFTFTPKPAPPSYQRWRVGALRIIDSKNYAGQKDVQALWTNDHALAWHLSDDFREDPVAWARTQCQAWEELEDQLPNFLEELPDCPCTLTQARADSGRFFTDYGCDMEQGSVCTYHPGAVHCVRSVQASLRYGSGQQCCYTADGTQLLTADSSGGSTPDRGHDWGAPPFRTPPRVPSMSHWLYDVLSFYYCCLWAPDCPRYMQRRPSNDCRNYRPPRLASAFGDPHFVTFDGTNFTFNGRGEYVLLEAALTDLRVQARAQPGTMSNGTETRGTGLTAVAVQEGNSDVVEVRLANRTGGLEVLLNQEVLSFTEQSWMDLKGMFLSVAAGDRVSIMLASGAGLEVSVQGPFLSVSVLLPEKFLTHTHGLLGTLNNDPTDDFTLHSGRVLPPGTSPQELFLFGANWTVHNASSLLTYDSWFLVHNFLYQPKHDPTFEPLFPSETTLNPSLAQEAAKLCGDDHFCNFDVAATGSLSTGTATRVAHQLHQRRMQSLQPVVSCGWLAPPPNGQKEGNRYLAGSTIYFHCDNGYSLAGAETSTCQADGTWSSPTPKCQPGRSYAVLLGIIFGGLAVVAAVALVYVLLRRRKGNTHVWGAQP

Protein

Sushi domain-containing protein 2: SUSD2

Gene

Susd2

Protein

Sushi domain-containing protein 2

Organism

Mus musculus

Length

820 amino acids

Function

May be a cytokine receptor for C10ORF99. May be a tumor suppressor; together with C10ORF99 has a growth inhibitory effect on colon cancer cells which includes G1 cell cycle arrest (By similarity). May play a role in breast tumorigenesis (PubMed:23131994).

Mass

90.641 kDa

Sequence

MKLALLPWILMLLSTIPGPGFTAGAQGSCSLRCGAQDGLCSCHPTCSGLGTCCEDFLDYCLEILPSSGSMMGGKDFVVQHLKWTDPTDGVICRFKESIQTLGYVDDFYQVHCISPLLYESGYIPFTISMDNGRSFPHAGTWLAAHPYKVSESEKSQLVNETHWQYYGTSDTRGNLNLTWDTSALPTPAVTIELWGYEETGKPYSGNWTSKWSYLYPLATNIPNTGFFTFTPKPASPQYQRWKVGALRISSSRNYPGEKDVRALWTNDHALAWHLGDDFRADSVAWARAQCLAWEALEDQLPNFLTELPDCPCTLAQARADSGRFFTDYGCDIEHGSVCTYHPGAVHCVRSVQASPRYGSGQQCCYTAAGTQLLTSDSTSGSTPDRGHDWGAPPYRTPPRVPGMSHWLYDVISFYYCCLWAPECPRYMKRRPSSDCRNYRPPRLASAFGDPHFVTFDGTSFSFSGNGEYVLLETTLSDLRVQGRAQPGRMPNGTQARGTGLTAVAVQEDNSDVIEVRLAGGSRVLEVLLNQKVLSFTEQNWMDLKGMFLSVAAQDKVSIMLSSGAGLEVGVQGPFLSVSILLPEKFLTHTRGLLGTLNNNPRDDFTLRNGQVLPLNASAQQVFQFGADWAVSNTSSLFTYDSWLLVYQFVYGPKHNPNFKPLFPDETTLSPSQTEDVARLCEGDRFCILDVMSTGSSSVGNATRIAHQLHQHRLKSLQPVVSCGWLPPPANGHKEGLRYLEGSVVRFSCNNGYSLVGPESSTCQADGKWSMPTPECQPGRSYTVLLSIIFGGLAIVALISIIYMMLHRRRKSNMTMWSSQP

Protein

Sushi domain-containing protein 2: Susd2