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SUMO4

Gene
SUMO4
Protein
Putative small ubiquitin-related modifier 4
Organism
Arabidopsis thaliana
Length
114 amino acids
Function
Ubiquitin-like protein which can be covalently attached to target lysines as a monomer. Does not seem to be involved in protein degradation and may function as an antagonist of ubiquitin in the degradation process (By similarity).
Similarity
Belongs to the ubiquitin family. SUMO subfamily.
Mass
13.409 kDa
Sequence
MSTTSRVGSNEVKMEGQKRKVVSDPTHVTLKVKGQDEEDFRVFWVRRNAKLLKMMELYTKMRGIEWNTFRFLFDGSRIREYHTPDELERKDGDEIDAMLCQQSGFGPSSIKFRV

Gene
SUMO4
Protein
Small ubiquitin-related modifier 4
Organism
Homo sapiens
Length
95 amino acids
Function
Ubiquitin-like protein which can be covalently attached to target lysines as a monomer. Does not seem to be involved in protein degradation and may modulate protein subcellular localization, stability or activity. Upon oxidative stress, conjugates to various anti-oxidant enzymes, chaperones, and stress defense proteins. May also conjugate to NFKBIA, TFAP2A and FOS, negatively regulating their transcriptional activity, and to NR3C1, positively regulating its transcriptional activity. Covalent attachment to its substrates requires prior activation by the E1 complex SAE1-SAE2 and linkage to the E2 enzyme UBE2I.
Similarity
Belongs to the ubiquitin family. SUMO subfamily.
Mass
10.685 kDa
Sequence
MANEKPTEEVKTENNNHINLKVAGQDGSVVQFKIKRQTPLSKLMKAYCEPRGLSMKQIRFRFGGQPISGTDKPAQLEMEDEDTIDVFQQPTGGVY

Gene
SUMO4
Protein
Small ubiquitin-related modifier 4
Organism
Sus scrofa
Length
95 amino acids
Function
Ubiquitin-like protein which can be covalently attached to target lysines as a monomer. Does not seem to be involved in protein degradation and may modulate protein subcellular localization, stability or activity. Upon oxidative stress, conjugates to various anti-oxidant enzymes, chaperones, and stress defense proteins. May also conjugate to NFKBIA, TFAP2A and FOS, negatively regulating their transcriptional activity, and to NR3C1, positively regulating its transcriptional activity. Covalent attachment to its substrates requires prior activation by the E1 complex SAE1-SAE2 and linkage to the E2 enzyme UBE2I (By similarity).
Similarity
Belongs to the ubiquitin family. SUMO subfamily.
Mass
10.775 kDa
Sequence
MADEKPKEGVKTENNDHINLKVAGQDGSVAQFKIRRHTPLSKLMKAYCERQGLSIRQIRFRVDGQPINETHTPAQLELEDEDTIDVLQQQTGGVY