SUB1

Subtilisin-like protease 1

533 amino acids

Secreted subtilisin-like serine protease with keratinolytic activity that contributes to pathogenicity.

Belongs to the peptidase S8 family.

55.699 kDa

MGVFRFISISLAAVSAANAAQILSMPHAQTVPNSYIVMMKDDTSDDDFNHHQSWLQSTHTHNITRRATIQNAGMRHKYNFSKMKGYSGIFDEETIKDIAKDPKVMFVEPDTIISVHGKVEQSNVPSWGLARISNPQPGAGSYIYDSSAGEGITVYSVDTGVDVNHEDFEGRAIWGSNQVNDGDDRDGSGHGTHTSGTMVGKEFGIAKKAKLVAVKVLGNDGSGPTSGIVAGINWSVEHARQNGGTKKAVMNMSLGGSSSSALNRAAAQAVEQGMFLSVAAGNDNQDAQSSSPASEPSVCTVGSSAEDDSRSSFSNWGPAIDLFAPGSNIISARPGGGSQSMSGTSMAAPHVAGLAAYLMALEGISGGAVCDRLKELGTSSITDAGPGTPTNVLINNGGAKGGKPNPNPAPSPSPSPSQPSEPQQPTPSQPGQPGEPFPGEPQQPTPSQPGQPGEPFPGEPFPGEPFPGEPFPGESFPGESFPGESAPAPAPMPPSPQHPHTPYPGGDNFDFDGLWKKYFGGEHWRKMFSSFWN

SUB1

Subtilisin-like protease 1

518 amino acids

Secreted subtilisin-like serine protease with keratinolytic activity that contributes to pathogenicity.

Belongs to the peptidase S8 family.

54.189 kDa

MGVFRFISISLAAVSAANAAQILSMPHAQTVPNSYIVMMKDDTSDDDFNHHQSWLQSTHTHNITRRATIQNAGMRHKYNFSKMKGYSGIFDEETIKDIAKDPKVMFVEPDTIISVHGKVEQSNVPSWGLARISNPQPGAGSYIYDSSAGEGITVYSVDTGVDVNHEDFEGRAIWGSNQVNDGDDRDGSGHGTHTSGTMVGKEFGIAKKAKLVAVKVLGNDGSGPTSGIVAGINWSVEHARQNGGTKKAVMNMSLGGSSSSALNRAAAQAVEQGMFLSVAAGNDNQDAQSSSPASEPSVCTVGSSAEDDSRSSFSNWGPAIDLFAPGSNIISARPGGGSQSMSGTSMAAPHVAGLAAYLMALEGISGGAVCDRLKELGTSSITDAGPGTPTNVLINNGGAKGGKPNPNPAPSPSPSPSQPSEPQQPTPSQPGQPGEPFPGEPQQPTPSQPGQPGEPFPGEPFPGEPFPGEPFPGESAPAPAPQHPHTPYPGGDNFDFDGFWKKYFGGEHWRKMFSSFWN

SUB1

Subtilisin-like protease 1

507 amino acids

Secreted subtilisin-like serine protease with keratinolytic activity that contributes to pathogenicity.

Belongs to the peptidase S8 family.

53.093 kDa

MGVFRFISISLAAVSAANAAQILSMPHAQTVPHSYIVMMKDDTSDDDFNHHQSWLQSTHTHNITRRATIQNAGMRHKYNFRKMKGYSGIFDEETIKDIAKDPKVMFVEPDTIISVNGKVEQSNVPSWGLARISNSQPGANSYVYDSSAGEGITVYSVDTGVDINHEDFEGRAIWGSNQVNDGDDRDGSGHGTHTSGTMVGKEFGIAKKAKLVAVKVLGNDGSGPTSGIVAGINWCVEHARQNGGNDKAVMNMSLGGSSSSALNRAAAQAVEQGMFLSVAAGNENQDARSSSPASEPSVCTVGSSAEDDSRSSFSNWGPALDLFAPGSNIISARPGGGSQSMSGTSMAAPHVAGLAAYLMALEGISGGAVCDRLKELGSSSITDVGPGTPTNVLISNGGAKGGNPKPAPGPSPNPSQPSEPQQPAPSQPGEPGESFPGEPFPGEPFPGEPFPGESSPGESAPAPAPMPPSPQHPHTPYPGGDNFDFDGYWKKYFGGEHWRKMFGSFWN

SUB1

Subtilisin-like protease 1

507 amino acids

Secreted subtilisin-like serine protease with keratinolytic activity that contributes to pathogenicity.

Belongs to the peptidase S8 family.

53.08 kDa

MGVFRFISISLAAVSAANAAQILSMPHAQTVPHSYIVMMKDDTSDDDFNHHQSWLQSTHTHNITRRATIQNAGMRHKYNFRKMKGYSGIFDEETIKDIAKDPKVMFVEPDTIISVNGKVEQSNVPSWGLARISNSQPGANSYVYDSSAGEGITVYSVDTGVDINHEDFEGRAIWGSNQVNDGDDRDGSGHGTHTSGTMVGKEFGIAKKAKLVAVKVLGNDGSGPTSGIVAGINWCVEHARQNGGTDKAVMNMSLGGSSSSALNRAAAQAVEQGMFLSVAAGNENQDARSSSPASEPSVCTVGSSAEDDSRSSFSNWGPALDLFAPGSNIISARPGGGSQSMSGTSMAAPHVAGLAAYLMALEGISGGAVCDRLKELGSSSITDVGPGTPTNVLISNGGAKGGNPKPAPGPSPNPSQPSEPQQPAPSQPGEPGESFPGEPFPGEPFPGEPFPGESSPGESAPAPAPMPPSPQHPHTPYPGGDNFDFDGYWKKYFGGEHWRKMFGSFWN

SUB1

Subtilisin-like protease 1

504 amino acids

Secreted subtilisin-like serine protease with keratinolytic activity that contributes to pathogenicity.

Belongs to the peptidase S8 family.

52.815 kDa

MGVFRFISISLAAVSAANAAQILSMPHAQTVPNSYIVMMKDDTSDDDFKHHQSWLQSTHTHNITRRATIQNAGMRHKYNFNKMKGYSGIFDDETIKDIAKDPKVMFVEPDTIVSVHGKVEQSNVPSWGLARISNPQPGADSYTYDSSAGEGITVYSVDTGVDVNHEDFEGRAIWGSNQVNDGDDRDGSGHGTHTSGTMVGKMYGIAKKAKLVAVKVLGNDGSGPTSGIVAGINWSVEHARQNGGTKKAVMNMSLGGSSSSALNRAAAQAVEQGMFLSVAAGNDNQDAQSSSPASEPSVCTVGSSAEDDSRSSFSNWGPAIDIFAPGSNIVSARPGGGSQSMSGTSMAAPHVAGLAAYLMALEGISGGAVCDRLKELGTSSITDAGPGTPTNVLINNGGAKGGQPNPNPAPAPSPSQPSEPQQPTPSQPGQPGEPFPGEPFPGEPFPGQPFPGESAPAPAPAPMPPTPQHPHTPYPGGDNFDFDSFWKKYFGGEHWRKMFSSFWN

SUB1

Subtilisin-like protease 1

485 amino acids

Secreted subtilisin-like serine protease with keratinolytic activity that contributes to pathogenicity.

Belongs to the peptidase S8 family.

51.283 kDa

MGIFRFISISLAAVSAANAGHILSMGHAKTIPNSYIVVMKDGTTEEDFTHHQSWVQSIHTHNVTRRGLLDNAGVRHKYGFGSMMGYAGLFDEDTIKDISDDPKVMFVEPDTTITIHGELTQNDVPSWGLARISSQRPGTEDYTYDSSAGEGITVYSVDTGVDIHHEDFEGRASWGTNMIEDGYDKDGNGHGTHTAGTMVGKTFGIAKKAKVVAVKVLDNNGSGPTSGIIAGINWCAQHASQNGGTDKAVINMSLGGGSSSALNRAAAQAVQKGMFLAVAAGNDNQDARTSSPASEDTVCTVGASAENDERSSFSNWGPAVDLFAPGSNIVSTRPGGGSQSMSGTSMASPHVAGLGAYIMALEGISGSAVCDRLKQLGTSSVTNPGPGTRTNILINNGDAKNGGKKPSQPSQPPKPSQPSKPQQPSEPQEPSEPQEPAPGQPAPAPAPVPQHPHTPFPNDDFNFDDFWKKYFGTDHWRKTFGRFWN

SUB1

Subtilisin-like protease 1

485 amino acids

Secreted subtilisin-like serine protease with keratinolytic activity that contributes to pathogenicity.

Belongs to the peptidase S8 family.

51.282 kDa

MGIFRFISISLAAVSAANAGHILSMGHAKTIPNSYIVVMKDGTTKEDFTHHQSWVQSIHTHNVTRRGLLDNAGVRHKYGFGSMMGYAGLFDEDTIKDISDDPKVMFVEPDTTITIHGELTQNDVPSWGLARISSQRPGTEDYTYDSSAGEGITVYSVDTGVDIHHEDFEGRASWGTNMIEDGYDKDGNGHGTHTAGTMVGKTFGIAKKAKVVAVKVLDNNGSGPTSGIIAGINWCAQHASQNGGTDKAVINMSLGGGSSSALNRAAAQAVQKGMFLAVAAGNDNQDARTSSPASEDTVCTVGASAENDERSSFSNWGPAVDLFAPGSNIVSTRPGGGSQSMSGTSMASPHVAGLGAYIMALEGISGSAVCDRLKQLGTSSVTNPGPGTRTNILINNGDAKNGGKKPSQPSQPPKPSQPSKPQQPSEPQEPSEPQEPAPGQPAPAPAPVPQHPHTPFPNDDFNFDDFWKKYFGTDHWRKTFGRFWN

SUB1

Subtilisin-like protease 1

481 amino acids

Secreted subtilisin-like serine protease with keratinolytic activity that contributes to pathogenicity.

Belongs to the peptidase S8 family.

50.605 kDa

MGVFRFISISLAAVSAANAAQILSMPHAQTVPNSYIVMMKDDTSDDDFNHHQSWLQSTHTHNITRRATVQNAGMRHKYNFHKMKGYSGVFDDETIKDIAKDPKVMFVEPDTIISVHGKVDQNNVPSWGLARISSSKPGTQDYTYDSSAGEGITVYSVDTGVDINHEDFEGRAIWGSNQVNDGDDNDRSGHGTHTSGTMVGKEFGIAKKAKLVAVKVLGNDGSGPTSGIVAGINWCVEHARQNGGTNKAVMNMSLGGGSSSALNRAAAQAVEQGMFLSVAAGNDNTDARSSSPASEPSVCTVGASAEDDSRSSFSNWGPSLDLFAPGSNIISARPGGGSQSMSGTSMAAPHVAGLAAYLMALEGISGGAVCDRLKQLGSASISDVGPGTPTNVLINNGGAKGDGKSPKPSPKPSHPSEPQQPTEPQQPAPGEPSTPAPAPMPPTPQHPHTPFPGGDDFDFDGFWKKYFGGEHWRKMFSSFFN

sub1

Subtilisin

420 amino acids

Subtilisin is an extracellular alkaline serine protease, it catalyzes the hydrolysis of proteins and peptide amides.

Belongs to the peptidase S8 family.

44.087 kDa

MKRSGKIFTTAMLAVTLMMPAMGVSANEGNAAAEGNEKFRVLVDSVDQKNLKNAKQQYGVHWDFAGEGFTTDMNEKQFNALKKNKNLTVEKVPELEIATATDKPEALYNAMAASQSTPWGIKAIYNNSSITQTSGGGGINIAVLDTGVNTNHPDLRNNVEQCKDFTVGTTYTNNSCTDRQGHGTHVAGSALADGGTGNGVYGVAPDADLWAYKVLGDDGSGYADDIAAAIRHAGDQATALNTKVVINMSLGSSGESSLITNAVNYSYNKGVLIIAAAGNSGPYQGSIGYPGALVNAVAVAALENKVENGTYRVADFSSRGYSWTDGDYAIQKGDVEISAPGAAIYSTWFDGGYATISGTSMASPHAAGLAAKIWAQYPSASNVDVRGELQYRAYENDILSGYYAGYGDDFASGFGFATVQ

SUB1

Subtilisin-like protease 1

399 amino acids

Secreted subtilisin-like serine protease with keratinolytic activity that contributes to pathogenicity.

Belongs to the peptidase S8 family.

41.427 kDa

single

MGVFRFISISLAAVSAANAAQILSMPHAQTVPNSYIVMMKDDTSDDDFNHHQSWLQSTHTHNITRRATIQNAGMRHKYNFSKMKGYSGIFDEETIKDIAKDPKVMFVEPDTIISVHGKVEQSNVPSWGLARISNPQPGAGSYIYDSSAGEGITVYSVDTGVDVNHEDFEGRAIWGSNQVNDGDDRDGSGHGTHTSGTMVGKEFGIAKKAKLVAVKVLGNDGSGPTSGIVAGINWSVEHARQNGGTKKAVMNMSLGGSSSSALNRAAAQAVEQGMFLSVAAGNDNQDAQSSSPASEPSVCTVGSSAEDDSRSSFSNWGPAIDLFAPGSNIISARPGGGSQSMSGTSMAAPHVAGLAAYLMALEGISGGAVCDRLKELGTSSITDAGPGTPTNVLINNGGA

SUB1

Subtilisin-like protease 1

399 amino acids

Secreted subtilisin-like serine protease with keratinolytic activity that contributes to pathogenicity.

Belongs to the peptidase S8 family.

41.427 kDa

single

MGVFRFISISLAAVSAANAAQILSMPHAQTVPNSYIVMMKDDTSDDDFNHHQSWLQSTHTHNITRRATIQNAGMRHKYNFSKMKGYSGIFDEETIKDIAKDPKVMFVEPDTIISVHGKVEQSNVPSWGLARISNPQPGAGSYIYDSSAGEGITVYSVDTGVDVNHEDFEGRAIWGSNQVNDGDDRDGSGHGTHTSGTMVGKEFGIAKKAKLVAVKVLGNDGSGPTSGIVAGINWSVEHARQNGGTKKAVMNMSLGGSSSSALNRAAAQAVEQGMFLSVAAGNDNQDAQSSSPASEPSVCTVGSSAEDDSRSSFSNWGPAIDLFAPGSNIISARPGGGSQSMSGTSMAAPHVAGLAAYLMALEGISGGAVCDRLKELGTSSITDAGPGTPTNVLINNGGA

SUB1

RNA polymerase II transcriptional coactivator SUB1

292 amino acids

Plays a role in the release of TFIIB from the transcription complex during transcription initiation. Binds to TFIIB and specifically inhibits the formation of the TBP-TFIIB-promoter complexes.

Belongs to the transcriptional coactivator PC4 family.

33.102 kDa

MSYYNRYRNKRRSDNGGGNLSNSNNNNGGMPSGLSASDAIFDLGKNKRVTVRQFRNINLIDIREYYLDSSTGEMKPGKKGISLTEDLYDELLKHRLNIDEALRRLGSKRPKTKMVRLLSDDEYEDDNNNDSTNNDKDKNGKDKNSPKKRREDKSKASNESHDLEPRSKKKKPAPPTLLPHEENIQNAEREANATLIIPGQAGRKQQEERKQKEKEEAEEAKAKAVAEQEKEAKAKEKIAEPEPEPVPTLQAKKEDIVSNINESKDANSSDEEFAQSLEAEMNKAEDDISEEE

SUB1

Activated RNA polymerase II transcriptional coactivator p15

127 amino acids

General coactivator that functions cooperatively with TAFs and mediates functional interactions between upstream activators and the general transcriptional machinery. May be involved in stabilizing the multiprotein transcription complex. Binds single-stranded DNA. Also binds, in vitro, non-specifically to double-stranded DNA (ds DNA).

Belongs to the transcriptional coactivator PC4 family.

14.395 kDa

MPKSKELVSSSSSGSDSDSEVDKKLKRKKQVAPEKPVKKQKTGETSRALSSSKQSSSSRDDNMFQIGKMRYVSVRDFKGKVLIDIREYWMDPEGEMKPGRKGISLNPEQWSQLKEQISDIDDAVRKL

SUB1

Activated RNA polymerase II transcriptional coactivator p15

127 amino acids

General coactivator that functions cooperatively with TAFs and mediates functional interactions between upstream activators and the general transcriptional machinery. May be involved in stabilizing the multiprotein transcription complex. Binds single-stranded DNA. Also binds, in vitro, non-specifically to double-stranded DNA (ds DNA) (By similarity).

Belongs to the transcriptional coactivator PC4 family.

14.395 kDa

MPKSKELVSSSSSGSDSDSEVDKKLKRKKQVAPEKPVKKQKTGETSRALSSSKQSSSSRDDNMFQIGKMRYVSVRDFKGKVLIDIREYWMDPEGEMKPGRKGISLNPEQWSQLKEQISDIDDAVRKL

Sub1

Activated RNA polymerase II transcriptional coactivator p15

127 amino acids

General coactivator that functions cooperatively with TAFs and mediates functional interactions between upstream activators and the general transcriptional machinery. May be involved in stabilizing the multiprotein transcription complex. Binds single-stranded DNA. Also binds, in vitro, non-specifically to double-stranded DNA (ds DNA).

Belongs to the transcriptional coactivator PC4 family.

14.427 kDa

MPKSKELVSSSSSGSDSDSEVEKKLKRKKQAVPEKPVKKQKPGETSRALASSKQSSSSRDDNMFQIGKMRYVSVRDFKGKILIDIREYWMDSEGEMKPGRKGISLNMEQWSQLKEQISDIDDAVRKL

SUB1

Activated RNA polymerase II transcriptional coactivator p15

127 amino acids

General coactivator that functions cooperatively with TAFs and mediates functional interactions between upstream activators and the general transcriptional machinery. May be involved in stabilizing the multiprotein transcription complex. Binds single-stranded DNA. Also binds, in vitro, non-specifically to double-stranded DNA (ds DNA) (By similarity).

Belongs to the transcriptional coactivator PC4 family.

14.395 kDa

MPKSKELVSSSSSGSDSDSEVDKKLKRKKQVAPEKPVKKQKTGETSRALSSSKQSSSSRDDNMFQIGKMRYVSVRDFKGKVLIDIREYWMDPEGEMKPGRKGISLNPEQWSQLKEQISDIDDAVRKL

Sub1

Activated RNA polymerase II transcriptional coactivator p15

127 amino acids

General coactivator that functions cooperatively with TAFs and mediates functional interactions between upstream activators and the general transcriptional machinery. May be involved in stabilizing the multiprotein transcription complex. Binds single-stranded DNA. Also binds, in vitro, non-specifically to double-stranded DNA (ds DNA) (By similarity).

Belongs to the transcriptional coactivator PC4 family.

14.441 kDa

MPKSKELVSSSSSGSDSDSEVEKKLKRKKQVVPEKPVKKQKPGESSRALASSKQSSSSRDDNMFQIGKMRYVSVRDFKGKILIDIREYWMDSEGEMKPGRKGISLNMEQWSQLKEQISDIDDAVRKL

SUB1

Activated RNA polymerase II transcriptional coactivator p15

126 amino acids

General coactivator that functions cooperatively with TAFs and mediates functional interactions between upstream activators and the general transcriptional machinery. May be involved in stabilizing the multiprotein transcription complex. Binds single-stranded DNA. Also binds, in vitro, non-specifically to double-stranded DNA (ds DNA) (By similarity).

Belongs to the transcriptional coactivator PC4 family.

14.237 kDa

MPKSKELVSSSSSASDSDSEVDKKAKRKKQAAPEKPVKKQKTGESSKGAASSKQSSNRDENMFQIGKMRYVSVRDFKGKVLIDIREYWMDQEGEMKPGRKGISLNPEQWNQLKEQISDIDDAVRKL