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SUB

Gene
SUB
Protein
Protein STRUBBELIG
Organism
Arabidopsis thaliana
Length
768 amino acids
Function
Regulates the expression of transcription factors that define the cell fates. Acts in a non-cell-autonomous fashion, functions in a radial inside-out signaling process, and mediates cell morphogenesis and cell fate across clonally distinct cell layers in floral primordia, developing ovules, and root meristems. Seems to be required for the regulation of cell shape and the orientation of the mitotic division plane. Involved in root hair specification, in the formation of the outer integument and the shape of organs such as carpels and petals and is necessary for the shape and height of the stem. Non-functional SUB proteins are retained in the endoplasmic reticulum and degraded by endoplasmic reticulum-associated degradation (ERAD).
Similarity
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
Mass
84.46 kDa
Sequence
MSFTRWEVFFGLSVLALTMPFSAGVTNLRDVSAINNLYITLGAPSLHHWLAFGGDPCGEKWQGVVCDSSNITEIRIPGMKVGGGLSDTLADFSSIQVMDFSSNHISGTIPQALPSSIRNLSLSSNRFTGNIPFTLSFLSDLSELSLGSNLLSGEIPDYFQQLSKLTKLDLSSNILEGHLPSSMGDLASLKILYLQDNKLTGTLDVIEDLFLTDLNVENNLFSGPIPPNLLKIPNFKKDGTPFNTSIITPPPPPVVDPPPATHRAPPVPRIPPVSGVPPAPFAPFAPLQPQQHPPPSPPLVWSPPSSDNGGGDPWNSVSGQPTLQISPPSGSGSGKFWSTQRIILVVSSVAIIVLVSGLCVTLWRCCRSKIYNRYYSGARKDLQRPYFNKPPSQPTPTMGKVSREPMVKPFDGYGAGDRKYGYPMPQRAEESRRAMPPTSYYNKDVNTPQKPLQQPPRQFQSNDTASKRAAHFPPGLNSSSSATVFTIASLQQYTNNFSEENIIGEGSIGNVYRAELRHGKFLAVKKLSNTINRTQSDGEFLNLVSNVLKLKRGHILELLGYCNEFGQRLLVYEYCPNGSLQDALHLDRKLHKKLTWNVRINIALGASKALQFLHEVCQPPVVHQNFKSSKVLLDGKLSVRVADSGLAYMLPPRPTSQMAGYAAPEVEYGSYTCQSDVFSLGVVMLELLTGRRPFDRTRPRGHQTLAQWAIPRLHDIDALTRMVDPSLHGAYPMKSLSRFADIISRSLQMEPGFRPPISEIVQDLQHMI

Gene
sub
Protein
Kinesin-like protein subito
Organism
Drosophila melanogaster
Length
628 amino acids
Function
Required during female meiosis for bipolar spindle formation in the absence of the centrosomes and chromosome homolog segregation. Also has roles in male meiosis and mitotic divisions of the early embryo.
Similarity
Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.
Mass
71.387 kDa
Sequence
MDSKEVSEVPRREVRSFLMARDPSIDRRFRPRPNKKMRLFDNIQESEEESFSEYSDTESEYKYQSSEATEGASCATSAADSSNVETGPQVFLRLRPVKDASKAYIVSEEANVLITSCKVDSTSNNVNRMEKHFGFTSIFDSTVGQRDIYDTCVGPKIMEEECVTIMTYGTSGSGKTYTLLGDDVRAGIIPRALENIFTIYQDTVFRSPKLKLINGSIVFLQDDASLKELQIRKKLLDLCPDISAHHQRLKQVIDGDHMFETKASTDVSVLVWVSFVEIYNELVYDLLAIPPKQDKLGEVPRKNLKIVGNKGHVFIKGLTSVFVTSSEEALRLLRLGQQRSTYASTSVNANSSRSHCVFTVDILKYNRSGITTQSSYKFCDLAGSERVNNTGTSGLRLKEAKNINTSLMVLGRCLDAASTVQKKKNADIIPYRDSKLTMLLQAALLGKEKLAMIVTVTPLDKYYEENLNVLNFASIAKNIIFKEPVIKQHRVSYCGFMEFSKMSTCEGGDYTKELEDENVRLQLEIEQLKYDHVLQMQLLEEKLRRELTATYQEIIQNNKKQYEDECEKKLLIAQRESEFMLSSQRRRYEEQIEDLKDEIEELKNPASDTDISDDPNESKSPIEILDDD