STRADB

STE20-related kinase adapter protein beta

418 amino acids

Pseudokinase which, in complex with CAB39/MO25 (CAB39/MO25alpha or CAB39L/MO25beta), binds to and activates STK11/LKB1. Adopts a closed conformation typical of active protein kinases and binds STK11/LKB1 as a pseudosubstrate, promoting conformational change of STK11/LKB1 in an active conformation (By similarity).

Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.

47.026 kDa

MSLLDCFCTSRTQVESLRPEKQSETSIHQYLVDEPTLSWSRPSTRASEVLCSTNVSHYELQVEIGRGFDNLTSVHLARHTPTGTLVTIKITNLENCNEERLKALQKAVILSHFFRHPNITTYWTVFTVGSWLWVISPFMAYGSASQLLRTYFPEGMSETLIRNILFGAVRGLNYLHQNGCIHRSIKASHILISGDGLVTLSGLSHLHSLVKHGQRHRAVYDFPQFSTSVQPWLSPELLRQDLHGYNVKSDIYSVGITACELASGQVPFQDMHRTQMLLQKLKGPPYSPLDISIFPQSESRMKNSQSGVDSGIGESVLVSSGTHTVNSDRLHTPSSKTFSPAFFSLVQLCLQQDPEKRPSASSLLSHVFFKQMKEESQDSILSLLPPAYNKPSISLPPVLPWTEPECDFPDEKDSYWEF

Stradb

STE20-related kinase adapter protein beta

418 amino acids

Pseudokinase which, in complex with CAB39/MO25 (CAB39/MO25alpha or CAB39L/MO25beta), binds to and activates STK11/LKB1. Adopts a closed conformation typical of active protein kinases and binds STK11/LKB1 as a pseudosubstrate, promoting conformational change of STK11/LKB1 in an active conformation (By similarity).

Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.

46.832 kDa

MSLLDCFCASRTRVESLRPEKQSETSIHQYLVDESAISRPPPSARASEVICSTDVSHYELQVEIGRGFDNLTSVHLARHTPTGTLVTVKITNLESCTEERLKALQRAVILSHFFQHPNITTYWTVFTVGSWLWVISPFMAYGSASQLLRTYFPDGMSETLIRNILFGAVQGLNYLHQNGCIHRSFKASHILISGDGLVTLSGLSHLHSLLKHGQRHRAVFDFPQFSTSVQPWLSPELLRQDLHGYNVKSDIYSVGITACELASGQVPFQDMHRTQMLLQKLKGPPYSPLDVSIFPQSDSRMRNSQSGVDSGIGESVLVSTGTHTVNSDRLHTPSTKTFSPAFFSLVQLCLQQDPEKRPSASSLLSHVFFKQMKEESQDSILPLLPPAYNRPSASLQPVSPWSELEFQFPDDKDPVWEF