Protein
3-beta-hydroxysteroid sulfotransferase
Function
Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the sulfonation of 3-beta-hydroxyl groups of neutral steroids. High preference for C21 steroid (pregnenolone).
Similarity
Belongs to the sulfotransferase 1 family.
Sequence
MSDNTLWFEGIRFPMVGFSPELLREVRDKFLVKDEDTITVTYPKSGTNWLIEIVCLILSKGDPKWVQSVPIWDRSPWIETQHGNELMKSQKDPRIYTSHLPLHLFPKSFFSSKAKVIYCIRNPRDVLVSGYYFTSKMKIAEKPETLQQYMKWFLQGNVIYGSWFEHVRDWLSMREKENFLVLSYEELIKDTRSIVEKICQFLGKRLKPEEIDLVLKYSSFKFMKENEMSNYSLLPNDLTTEGFTFLRKGVVGDWKHHFTVAQAEEFDKIYQEKMAGYPPKLFPWEEC