Protein
Negative regulator of pleiotropic drug resistance STB5
Organism
Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65)
Function
Transcription factor that negatively regulates pleiotropic drug resistance genes, including the ABC transporter genes CDR1, PDH1, and YOR1.
Sequence
MSGPDKGSDSGQTANDPKQKKARNGQMETYSCARCRKLKKKCPRQLPECSNCLKAREPCNYPGRAPRRTKKELRDAIMKGEVLPSMRRKHRKIEKELKTADLRHLESVDDRPVNQVMGGSMPPLGAYRGGEQQYNNGPPISGIDGNDSINRGKAQSVGSYQILPPQRKSKLVLDQNPKFVHSQSSALKTNEYPVPIMSPHIANQVYPEGVSSLISALNTMNDNVSANTPIALSYLQLQKLHQEQQQIQQQQIQQQQQHQHLVQQHLQHVRADATSILPPVTSQTVYTPIPGPRTSQIPFGFTHGYTASAPPPLMQPYSMPTSPFESREKQQQFDNIQYHPVYKIPPIAARQSPIDEIIGIENGSISIDAGSITREVVNSRMKGPHSTSWVNEDGSPKPIKKSLLEKFVSAYFEHNHRLFPMVDKVTFLKKLATINSFESIEMLAVNNPELPKTFIFEIYMIMAIGCTTLQRAGKLTTDEGHLYEHLAYLAMRNFRDILHQQDITTLRCLILLGIYSFFEPKGVSSWTISGIAMRLAIELGLNRPLTAKEMGDMSAVEVESRYRVFWSAYCFERVVATSLGRVSAIDDEDIGIPLPRALYDSEKEDIEVTNLIISLRKMGGKIYKEVHSLSAGRKDITMEQKQLIIQKLRKELDDIYEEECEKRRLKGKSRSSKRFEKSKESDSDRGVTEEDVKSGNENLIGLLASDDVSMTEHGQSIDNTLESTPLPTTIPTTIVNDSVDQHSTLENIPTSATSKDQIETIITKPTANIMNDQTDSDPLPKVDNKPISNNEEGPKSLKEGNSEQNPSENISPEDVTLTKTDNSENKESSLRSNSNISFHISNVWLEMRYTQLQILLYRPSALIPKPPIESLTVLGEFCLAAWRHTYTLYKEKLLPLNWITLFRTLTICNTILYCLCQWSIDLVASTIEIQQCVEILQHFGEKWVFAMKCADVFQNISNTIVEISLSQGQDPNIDKLTRELFGASNAYLEILNENNVDVSWEDRFR