STARD8

Gene

STARD8

Protein

StAR-related lipid transfer protein 8

Organism

Homo sapiens

Length

1023 amino acids

Function

Accelerates GTPase activity of RHOA and CDC42, but not RAC1. Stimulates the hydrolysis of phosphatidylinositol 4,5-bisphosphate by PLCD1.

Mass

112.601 kDa

Sequence

MTLNNCASMKLEVHFQSKQNEDSEEEEQCTISSHWAFQQESKCWSPMGSSDLLAPPSPGLPATSSCESVLTELSATSLPVITVSLPPEPADLPLPGRAPSSSDRPLLSPTQGQEGPQDKAKKRHRNRSFLKHLESLRRKEKSGSQQAEPKHSPATSEKVSKASSFRSCRGFLSAGFYRAKNWAATSAGGSGANTRKAWEAWPVASFRHPQWTHRGDCLVHVPGDHKPGTFPRSLSIESLCPEDGHRLADWQPGRRWGCEGRRGSCGSTGSHASTYDNLPELYPAEPVMVGAEAEDEDDEESGGSYAHLDDILQHVWGLQQRVELWSRAMYPDLGPGDEEEEEATSSVEIATVEVKCQAEALSQMEVPAHGESPAWAQAEVQPAVLAPAQAPAEAEPVAQEEAEAPAPAPAPAPAQDSEQEAHSGGEPTFASSLSVEEGHSISDTVASSSELDSSGNSMNEAEAAGPLAGLQASMPRERRDSGVGASLTRPCRKLRWHSFQNSHRPSLNSESLEINRQFAGQINLLHKGSLLRLTAFMEKYTVPHKQGWVWSMPKFMRRNKTPDYRGQHVFGVPPLIHVQRTGQPLPQSIQQAMRYLRSQCLDQVGIFRKSGVKSRIQNLRQMNETSPDNVCYEGQSAYDVADLLKQYFRDLPEPIFTSKLTTTFLQIYQLLPKDQWLAAAQAATLLLPDENREVLQTLLYFLSDIASAEENQMTAGNLAVCLAPSIFHLNVSKKDSPSPRIKSKRSLIGRPGPRDLSDNMAATQGLSHMISDCKKLFQVPQDMVLQLCSSYSAAELSPPGPALAELRQAQAAGVSLSLYMEENIQDLLRDAAERFKGWMSVPGPQHTELACRKAPDGHPLRLWKASTEVAAPPAVVLHRVLRERALWDEDLLRAQVLEALMPGVELYHYVTDSMAPHPCRDFVVLRMWRSDLPRGGCLLVSQSLDPEQPVPESGVRALMLTSQYLMEPCGLGRSRLTHICRADLRGRSPDWYNKVFGHLCAMEVAKIRDSFPTLQAAGPETKL

Protein

Gene

Stard8

Protein

StAR-related lipid transfer protein 8

Organism

Mus musculus

Length

1019 amino acids

Function

Accelerates GTPase activity of RHOA and CDC42, but not RAC1. Stimulates the hydrolysis of phosphatidylinositol 4,5-bisphosphate by PLCD1 (By similarity).

Mass

113.021 kDa

Sequence

MTLNNCASMKLEVHFQCKQDDDSEEEEQCTISSHWAFEQESKCGSLMGSSALLAPPSPSLLGTSSCESVLTELSAASLPAISASLSPESADQPLLGLVPSPSNQPFLSPPQGQEGSQDKVKKHYSRSFLKHLESLRRKEKGDSRQTEPEQCLATSEKATKASSFRTCRGFLSAGFHRAKNRVTTSARVRDGETQKAWEAWPVATFRHPQPIRRRDYLVHVPGDHKPGTFPRSLSIESLCPDEGRHLADWQSSRCWGYEGRRGSCGSTGSHASTYDNLPELYPAEPIQAEAEAEAEEGEGSYAHLDDILEHVWGLQQRVELWSQTMYPDLRPGDKEEEEEEEEEEEEATSSVEVATVEVEGQDEDLAQAESQAHRGFPTQVKEEVPLIVLDQAPNVVEPLVQAEAEAPAQAQDLEQEANSTAEPISASSLSVEEGHSISDTAVSSSELDSSGNSMNEADAADAPAGLQASVPRERRDSGVGASLTRPCRKLRWHSFQNSHRPSLNSESLEINRQFAGQINLLHKGSLLRLTGFMEKYTVPHKQAWVWSMPKFMKRNKTPDYRGHHVFGVPPLIHVQRTGQPLPQSIQQAMRYLRSQCLDQVGIFRKSGVKSRIQSLRQMNENSPDNVCYEGQSAYDVADLLKQYFRDLPEPIFTSKLTTTFLQIYQLLPKEQWLAAAQAATLLLPDENREVLQTLLYFLSDIASAEENQMTAGNLAVCLAPSIFHLNVSKKDSSSPRIKSKRSLVGRPGPRDLSENMAATQGLSHMISDCKKLFQVPQDMVVQLCGSYSAAELSPPGPALAELRQAQAAGVSLSLYMEESVQELLRDAAERFKGWTNVPGPQHTELACRKAPDGHPLRMWKASTEVAAPPAVVLHRVLRERALWDEDLLRAQVLEALMPGVELYHYVTDSMAPHPCRDFVVLRMWRSDLPRGGCLLVSQSLDPEQPVPESGVRALMLTSQYLMEPCGLGRSRLTHICRADLRGRSPDWYNKVFGHLCAMEVAKIRDSFPTLQAAGPETKL

Protein