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SSN2

Gene
SSN2
Protein
Mediator of RNA polymerase II transcription subunit 13
Organism
Debaryomyces hansenii (strain ATCC 36239 / CBS 767 / JCM 1990 / NBRC 0083 / IGC 2968)
Length
1774 amino acids
Function
Component of the SRB8-11 complex. The SRB8-11 complex is a regulatory module of the Mediator complex which is itself involved in regulation of basal and activated RNA polymerase II-dependent transcription. The SRB8-11 complex may be involved in the transcriptional repression of a subset of genes regulated by Mediator. It may inhibit the association of the Mediator complex with RNA polymerase II to form the holoenzyme complex (By similarity).
Similarity
Belongs to the Mediator complex subunit 13 family.
Mass
199.037 kDa
Sequence
MPEAIDASSIATNYYKLAHLCSVTYLIYTTNGATNDSTLLELELLIRHSHPKCLVTYYNKYLYYFQFNHVDEHVDLTKEYPQLQLKYSNQVSADLLANPPKVASDKDNHSTGNEYLAYACLSFLKAVKKLVLFNLSRNEAVQLFGNYAVVKEQGLSNFILHIDPILLPNGDLLISISEKCHLQLFDSSIVDISEIEAVDLNFVLYIIPSGIRCHLYDNVNVASNFTTDPPKNSEVLMQLIKYSTGFDLNQLNSLVWVKLVPNLQHLNNQTSKISKFIHPVDNKKFILWPWRLCLLQFGLSEKDTATSPHVLTCDPISLISDFIDFNISHHQQANITGQLNPNHQHNQSFNYSIPSALSTGMSSTGANENKGDLNMVGDIPGSVSDIFGIQSSDTNDFFNGPNFQPAQNPSDVKLDSQEPVKKNSDDEDVEMDDLFGDASEDEKAKTEVSTNELNEEKNFEDLFNDGLNQENQVDESDKVAKSIDEEVLKEESVKSEDLKEDKDLKMQPSSGTIPNTFIDIPKDQMTIPSLKNLKQTPQIYNDPGAPMPVIPTPIFPQFGINSTLPGSAQSVNPPTSAAATDNEANEGARSIFSPILFNPIIKSNIDTKYGKGGKFYVDKEVSAGPDIDSKRKTLRATSVSGFELPSRREDSIGIESITDDNDRRQVFEFPEEQGNERMKDEGHENHAAENDNIIKKMEELEEEDDNDDDDDDDDDDDENEDEDEESDEDDDLNLENNDMNMKRSPPLKLNTLNDPYVAQSNQAVVNFNDSNYNAKQILPNSYNASSMNTGGFSSPASLGFSSSRTNVPPKNDSPFGLNNLAREDRNGTTSPTGDNSDQPTKRQEQSDSPMVVDMEVEKKSTSKEAENTPSGMTTPNSRGSISESSNCLPLILRGVNVASIPTSFILNNVIVSNKISTISTNFDMDVDDETEWSDYELCKNNEMTVKLNNLDEFLKCLGPNLIFDMGLNKLQNSLEMKLSNNERDDEEYDNIEGKAPSRQFENKLCDIFPFCYKVNLNEFTTEAYVNELKGETTTIQDELDNQLSFLDDITNEDILNPKTQLKKLNSIEWDAIYSDSSSNEDNSKKYQGMVHNVGQSSLVNTLEDGTIFPLANDKARVLKHNDTIINLNSIGIKFWKYLNFSPLNGPKNFQLLLISEHDHNMLHHNYNIEFLNSLVYNYKECCFGNISKINLQSSDSRPDMEGIDNGLLMVHKKDEDQVYGNMYKQVNRKLNALVEMIKSDLINKTNKFEFDRPLLLLFINFDKSVNSLLQISKLIRNFKLFLSHHQLPLVEVFAHIIPWSLIIKQSGSQRRLKYLSNFRLSKLSMNLYNQCPNERTIGKPVKDPTKHLFTQLVKEPPSNLNFKFMNNGSNGNGKTTFNDDIFLHLAYERSIDKNWFSAAWSDPLGVVVSTKSWNCSPNLQKTNNKNVHSLESISDEIWTISTALFKKLNDEIIKRTSGLGGKKFLVLTRINSIIPDDELIHWKRLSMKHKDVSLIVLSVNKSPKLLFSGPIGPSQQEDKSNYDPNTNRTSTNMDNSSSTNAANPTCGVGATSNAPDFFKTFGSNNPSPNNNAGSMSISPSNNVGINFHSPQQFLNAPGNFLLPQDFVSSTGGSTNINANPHSNASQYNPDEIIHDPTEELTAVIPKAPLPSFNSPTRLGMKIGYLIKETGVSTHEDTKQYLVYEINLLSCSNYWNLNAIMKILLNQYKKLITLNDILCVGEIDGSITDDRAEKDSNIIPEMTPPLNYTASGLIPWHIAAVTKSLDYLIHIDVEE

Gene
SSN2
Protein
Mediator of RNA polymerase II transcription subunit 13
Organism
Candida albicans (strain SC5314 / ATCC MYA-2876)
Length
1665 amino acids
Function
Component of the SRB8-11 complex. The SRB8-11 complex is a regulatory module of the Mediator complex which is itself involved in regulation of basal and activated RNA polymerase II-dependent transcription. The SRB8-11 complex may be involved in the transcriptional repression of a subset of genes regulated by Mediator. It may inhibit the association of the Mediator complex with RNA polymerase II to form the holoenzyme complex (By similarity).
Similarity
Belongs to the Mediator complex subunit 13 family.
Mass
186.571 kDa
Sequence
MVGANASSISTQYYKLAHLGSISYTIYTSSDNNDQALLELELTIRHKWPQILVTYYNKSLYYFVFGHNKVDSETIDLTKEFPQLSTKYTDTVNVDQFPNPHKSTKNDDNLAWASLSFLKATKKMILYNLSLSGAIKLFGNYCVAPTGDSVYSILCIDPILFQNGDLVVSCVEKPFTQLFSSSVAYPRNLAIDTNFVIYLIPSGIRCHLFDPTSLRNNLIEKPQIENGKLLELLKITTGVQCDESTLWVKLIPNLKHLNNQTSAIGKFIHSVENKKFILWPWDLCLLQFGKFEPAIEEEGLLESSELNNPLHLISDFLDFRIAHNTQLQQQRDSLSDQQQGETVNVPLSAGSVHATGANSFGNVPDISKDVDTVGLSTTTPIETDLFNLQNTEEFFKNDSIHMNLEDQIHKKETEPENESENDMEIDDLFGGDESDDNDDLEEAGNEEEKPTPSNNTIDKNGVIGNALEEAFIADATPSKENINLDSKIMPPDSTSEEAVPDKENFKPKETKPSYIDILKDKMTIEKIVNSPDYKDPGAPLPVVPTPLVSSTVSQSAVTTNPPSVGSAPGPAPGPAPGTETLYEANNAYAQSSQISQLPQQKSAFSPILFNPIIKSDIDTKYGKGGKFYVAKDSSTNGNLDMKNRSLRATSVSGMEIPFSSEDKKRLQQNLEVLDSSTTSDNEGGEDIEDDDNDYEDEGDDDEEEEGEEEEEEESDEDEISDIGKSTPLKLNTQNESVPPQQSNYNPVNITDSGSNTTNNITDKQGYENTEGFGTPFPNQISKYSIKPESPFASNELQSSVSPMYFDTSQSHQSPQLQPSTGTLEVLKASSLESPSKISESSNYLPLILRSINVSTIPSSYLMNNLISSKLLPSFTISDDDLENDLDITKSNEMIVKLGFLKEFLDFMSPNIIFDLGLMKNDESDYYINGVNDLLLNSDPGISSDWILNSLSKVFPCTYPMKLIELLYDFKSLELEDQLDSQLNFLNEIADEEDFVGPKALYRKLKALEWDSFSLNESNKTSFEKYKNVMEKLSAENTVSDDDYFKLPMVKTRILKNGNIVNLNNIGLKFWKYLNFSPVKKQKDFQILLIAETHRNTASYATEFLDQIIQNYKECNFGTISKVNLSTVETRSDLEPISDGLVLVHKEHDQSYNDFYIQTNKKLISLVELIKLDLINKTNNFEFGKPLLLFFIDFNDSSNSNVQVCKIFRNFKVALTTHQLPLVDIFTKIVPSSLLVKKVHHETALKVFSNYKLTKISMNLYNECPNDLANKSIVKNLFTTIVKDPPSKIQFKFMNSSYRDNSSNDDIFLHLAYERSIDNSWFVASWSDPLGRVVHVKSWYCSDSVSKSEKSTYRGDIMDIMSITDDIWSISTDLFKVLNDELGSFGGKKFLVLTRINSIIPDVELVHWKRLSSKHKEISLIVVSVRQTPRIVGSNESEDLGPKSNDYAPTPMIQDKDIFFGFKQTFSTSNTSSPSASGGALVTSPNSLSLHSPQQFLNAPANFLSPQDLIAPTSSGISGAKPGSSGIDPEVVLENQDNEVYGVIPKVPLPSFNSPTRFCMKTGYLMMQVNQPSEEEYKDDIKKTYLVYEINLLSCSNYWNLDVLMKLIMSQYKQMIALNDILCMNPIVGESDILGTHSRNNAIVPWHINAVGKLLDYLVHIYVDKD

Gene
SSN2
Protein
Mediator of RNA polymerase II transcription subunit 13
Organism
Scheffersomyces stipitis (strain ATCC 58785 / CBS 6054 / NBRC 10063 / NRRL Y-11545)
Length
1660 amino acids
Function
Component of the SRB8-11 complex. The SRB8-11 complex is a regulatory module of the Mediator complex which is itself involved in regulation of basal and activated RNA polymerase II-dependent transcription. The SRB8-11 complex may be involved in the transcriptional repression of a subset of genes regulated by Mediator. It may inhibit the association of the Mediator complex with RNA polymerase II to form the holoenzyme complex (By similarity).
Similarity
Belongs to the Mediator complex subunit 13 family.
Mass
185.501 kDa
Sequence
MSEATASNISTHYYKLGHLGTVSFYNYVSFTDNDQSLLELELSIRYAHPNILVTYYNKSLYYFTFGHNNVPLETVSRDIELPDLAKDINTDVDLSKDVTGPNPGANNSPSLLANPPKSASSGSTLGAAVDEYLPFASLSLLKSIKKMILFNLSKNGAIKLFGNYCVVARDTINRSILYLDPILFPNGDLLLSMVVKERINLLDSSIIDLKYPSQDAPDINFVIYLIPSGIRCHLFDPTNLVRNFVRKKSAESENLIDLIKLSTGVEYSFNSEEENVWIKLIPNLKHLNNQTSTIAKFIHSVDNKKFILWPWKLCLLQFGKFEEVDEITSPDVTSSQVHPTSNPLDLIGDLIDFNISSNQHHNFAQPSQTLPFSISSVASTGGDAGIGSVDPHTTMEQQPHTLDLNDITTHMVPDLFDLQNPVPSEFFTKEVQDMPPVDGTEVKEDTNQDDVEMDDLFGGSDDEGDDSRNGQNSSKEDLFSDAIKEEPKDALAAGTPAELEKNQLNDLFDISDKEAAPDSGKYSTPAKEPKFKYLDIPKDQMTIKKSSSPDYNDPGAPLPIMPTPIIPVANSVYSTNPPTAAAIGTEGVGLSDDQSSGPYNQPQPKQEIFNSGSSASQIQQKSIFSPILFNPIIKSNIDTKYGKGGKFYVDKEASIGPEEKKKKTFRETSVSGYELPLTKEEDKLPITAQAVGLRKMNNSSLSLAESSMSASSEESDEDEEMPDVISNSPPLRLNTFNDSFGGVPMGNSGGITLNNNPINLSNYNTGGFGSPNSSVIGRFPNIKGESPFSTADLQQTVSPIDYEQSNNQHTPSFPTSQGLQITQSVNNGSGRTSSSDESPVKGISESSNYLPLILRSINVSTIPDIYLLNNLISDQLLPSFTINDDDNDNDLEVMRNNEMFIKAKHLDEFLELIGPNLVFDLGFNQGRSKLSYYMDELVKSKLEENKVFPNSYKVNLIEFLNDQKDYESKDELEDQLDFLDDIANDDDNILNPKSQYKKLKSIEWDALTENTKNKENFEKYKLIVNKLNSSVSTKDEVYFKLPIIKARVLKHNNILNLNNLAINFWKYMNFSPIKSTKHFQVLLISENNGNGTSFLREFLDLLIYNYKECNLGHISKVNLSTVETRPDLENINDGILLVNKDNDQTYNDTYSQINKKLNSLVELIKLDLINKTNNFEFDRPLLLLFVNYNDNLNSTLQISKVFRNLKVSLTNHQLPLVSIFTKIIPGSLIVKQDPFQNWLKVLSNFKLSKLSMNLYNQCPNGSTNKDIVKNTFTQLVKEPPSRIQFKFMSNNFKHSNFNDDIFLHLAYERSIDRNWFSAAWSDPLGVVTFTKSWYCSNKATRNGSGGYGRDTHDVATVCEEIWNKSNELFKKLNDEMNNESSTMGGKKFLVLTRINSIIPDDELIHWKRLSVKHKDISLIVLSVSHSPKLIFQDNRPRFEDTENCGQLDNFFKVFSGSNNSSPTTGGALVTSPNVLSFHSPQQFLNAPGNFLSPQDFVSTAGGAGAGATSAPHGGSNNPDLILHDFGTDVIGIIPKVPLPSFNSPTRLGMKIGYLLKEWMNGSRSTSRPRRSYLVYEVSLLSCSNYWDLDVLMKLILNHYKNLIVLNDILGLRKIDGNISKNESEDDFEQSLEFEASGIVPWHISAVGKSLVYLSHIYVDE

Gene
SSN2
Protein
Mediator of RNA polymerase II transcription subunit 13
Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
Length
1420 amino acids
Function
Component of the SRB8-11 complex. The SRB8-11 complex is a regulatory module of the Mediator complex which is itself involved in regulation of basal and activated RNA polymerase II-dependent transcription. The SRB8-11 complex may be involved in the transcriptional repression of a subset of genes regulated by Mediator. It may inhibit the association of the Mediator complex with RNA polymerase II to form the holoenzyme complex. The SRB8-11 complex phosphorylates the C-terminal domain (CTD) of the largest subunit of RNA polymerase II RPB1 at serines 2 and 5.
Similarity
Belongs to the Mediator complex subunit 13 family.
Mass
160.001 kDa
Sequence
MSSDASTYRLEDVLSSFYRVEKIKKINYHQYISKAQNDQWSIQMEFMLRKQDPKTLVALLSRDLWCFSINDDPVPTPPAIEHKPVSPDKIGTFTADYSKPNLPPHYALFLKALRRKIYINLALGSHNKLIQFGNACISLSGVPNYLVQLEPHLFVNGDLTVSLCAKNMGLVPMKEENLEESFLSKHALYLAPSGIRMHLAPASKQGYLITPPKHTELLLTTLSVSHGINLQNKKNLKWVAVVPDLGHLNGHTPTIASYLTPLLEAKKLVWPLHLIFAQPVADIENSTSGDPSEFHCLQDALDAIDDFIQLKQTAAYRTPGSSGVLSSNIAGTNPLSSDGAYTEQFQHYKNNSISSQPASYHSVQETNKISPKDFSPNFTGIDKLMLSPSDQFAPAFLNTPNNNINENELFNDRKQTTVSNDLENSPLKTELEANGRSLEKVNNSVSKTGSVDTLHNKEGTLEQREQNENLPSDKSDSMVDKELFGEDEDEDLFGDSNKSNSTNESNKSISDEITEDMFEMSDEEENNNNKSINKNNKEMHTDLGKDIPFFPSSEKPNIRTMSGTTKRLNGKRKYLDIPIDEMTLPTSPLYMDPGAPLPVETPRDRRKSVFAPLNFNPIIENNVDNKYKSGGKFSFSPLQKEEALNFDISMADLSSSEEEEDEEENGSSDEDLKSLNVRDDMKPSDNISTNTNIHEPQYINYSSIPSLQDSIIKQENFNSVNDANITSNKEGFNSIWKIPQNDIPQTESPLKTVDSSIQPIESNIKMTLEDNNVTSNPSEFTPNMVNSEISNLPKDKSGIPEFTPADPNLSFESSSSLPFLLRHMPLASIPDIFITPTPVVTISEKEQDILDLIAEQVVTDYNILGNLGIPKIAYRGVKDCQEGLITTTMLQLFSTFDRLNGNDTISKFYNMKQPYVFVKKHHELIKVKHDSQPFIKFLNFRPPNGIKNFKSLLLSSSFKEDCLSFAPTLSQTYINQELGFCELLKLTNEDPPGLMYLKAFDKNKLLLLAAQIVSYCSNNKNSIKNVPPILIILPLDNATLTELVDKANIFQVIKNEVCAKMPNIELYLKVIPMDFIRNVLVTVDQYVNVAISIYNMLPPKSVKFTHIAHTLPEKVNFRTMQQQQMQQQQQQQQQQQNNSTGSSSIIYYDSYIHLAYSRSVDKEWVFAALSDSYGQGSMTKTWYVGNSRGKFDDACNQIWNIALNLASKKFGKICLILTRLNGILPDDELMNWRRLSGRNIHLAVVCVDDNSKISFIDEDKLYPSFKPIYKDTRFGGRMDMTRLYDYEIRDIDQDIHGIVFQHPFPLAHSQHRCAIRSGALIKFKKCDGDTVWDKFAVNLLNCPHSDSTQLLETILEEFRNLAALNVWYGLSDGEDGHIPWHILAVKKMMNTLVHTRVKIANTSAATVHTATSSSIILSDK

Gene
SSN2
Protein
Mediator of RNA polymerase II transcription subunit 13
Organism
Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37)
Length
1387 amino acids
Function
Component of the SRB8-11 complex. The SRB8-11 complex is a regulatory module of the Mediator complex which is itself involved in regulation of basal and activated RNA polymerase II-dependent transcription. The SRB8-11 complex may be involved in the transcriptional repression of a subset of genes regulated by Mediator. It may inhibit the association of the Mediator complex with RNA polymerase II to form the holoenzyme complex (By similarity).
Similarity
Belongs to the Mediator complex subunit 13 family.
Mass
155.993 kDa
Sequence
MKKEVGDACRLEDIVTNLYRLETVKQINYHQYVPSKADNQWSIQAELFLRRKNPKVLAALFSRELWCFSINDDPLPELNLELNNESESPQPERKGHFTPEFSKPHLPTPYAIFMKALRRMIYVNLTLSSNETIVPFGNSCIFQESYTFSTKILHFDPHLFENGDLTVAICSKDLGLSKLNAESLKHEVAVYLAPSGIRVYLPSTDLKKCYVSPPKNAQMFLKTLFVSHGINLIDVDGLKWVKLIPNANHLNGFTPTISHYLDEPKGNNFVIWPACLCFVQTASDVQTPQYTAFSRSPQLELDDCFDMIDGFIQLKLTSAYRTPGTSAGMGTVTGHNPLSTGGIFTDQFQGFNKHSANNSNNVSSTGENGKFSPEYSNDPNVTPLRDNKTSRQNFPTESYSSNGFITTPIINENITPTVDDIITETPSVKPQNDLWNEKKDVINSTSNINSKDASVGSSERKVELETAFESPAQNISIEEHEHVEFDKDLFGEDSDEDVSTRNKNEELVSVKEITDEMFDLAEDDDEADGSTSNSLKFDRPDTIESIDTDEKKTRTKRTYLDIPVDVITIEKTPTLYEDPGAPLPIETPKDRKKSIFAPLNFNPIFESNVDNKYKNGGKFSVNSNTNDEPIQFGISTSNISSSEDDDSDFSPADFNNNGPSAGKGLSYDPRDNDIPMIESSTYEPIAKDSLPELINPPSSSKDDSVASYNTIGTLMEKPVKSNLDAIWKPALSKSERADLPNQTINGVINDCNNSSNSNPTTYFENTPSLGPDTLYDNSKPRSSSANFLSTVEIDPKSEQTIQTAEQEQSESSRILPYLLRHMPLFSLPDVFLCQNPSLPPGKDFEDILEILTDQIVFNNDMFSDDRATESQFKGIKDCSVGTISDTMNQLFGNFSKLHGNEIIEEVFYLPEPSVFVKKSEDTIKIKSSSCYFTEYLNLKPNRGVKNFRALVLTTEAKNDCMSFVSQMSQTYSNHELGFCELTKLTNDDNKGLIYLKNFNQDTLLLLSAQIVSFCSTALSNIKNIPLLIFLPINKLSLTECISMILKFHVIRKEFKSKLPKADILLRLVNIDFLKNPLTPITAYTSLCMAIYNSLPPKSTKVTSLTNDLPKQIEFRTLKNASLSIHYDNYIHLAYLRSIDREWLCAAWSDTKGVESFVKTWYVGNSRTRFEQVCNDIWKITLQLASKNFGNVCLVLTRLDSVLPDDELIHWRRLSVATKDLHLAVVCVGDNTKLTLFDEDKTYPTFKNLFRTKSNPQTGISNSIDDLEIINIDEEVHGLIFSNPLQLANSQHRCAIKSGALIRFAKSEGDNFIDKFEVNLLNCPHADSSTLLKEILKQYRNLAGLNPWFGVSYGKDNFIPWHVVAVKNVMNSIVHVKSSFEKETHIID

Gene
SSN2
Protein
Mediator of RNA polymerase II transcription subunit 13
Organism
Phaeosphaeria nodorum (strain SN15 / ATCC MYA-4574 / FGSC 10173)
Length
1375 amino acids
Function
Component of the SRB8-11 complex. The SRB8-11 complex is a regulatory module of the Mediator complex which is itself involved in regulation of basal and activated RNA polymerase II-dependent transcription. The SRB8-11 complex may be involved in the transcriptional repression of a subset of genes regulated by Mediator. It may inhibit the association of the Mediator complex with RNA polymerase II to form the holoenzyme complex (By similarity).
Similarity
Belongs to the Mediator complex subunit 13 family.
Mass
150.059 kDa
Sequence
MKASEMARPPMRPGNPHAFASPATTPSRTASPNNAQGANVRTTQGGNQAGASEQQQPLDCFVVYELFASAVTALVSFFLVKDCGAVALNYRTFVSKVEPQQEEGKIVTDLDRLYWLTSVHVHWFSSGTLLVSTSTERTLALQCLGDLSEDEQQKLVDRCIRVAPNAMLASISSFDDPRQLSADDSNRRTSKKKAKMDSLEQNIEKWRMSVQRWLSRRGYSLPNLDKNSAWVTIRVGQLAQFPAMSPHLPTSARDVLWPRSLCFMQSLVPDDLKWFEVPGSAGFRDPIDAAQDWFTGQLERDKILDMQRKAKKAEEDAMRRKDEAPGLYPSSPFTARTGVYGDLQPVSGVYPTPPDGIVPGTGISSTDTPSVSGTASNVVLVPGGNTPAINLSAPQDYTTTDNQQHASTSPTFPAPLEPFQTSGEDDDLFEDMEGDGFGGPDVEEADFDFFDGPDGDDVNMADAPALPETTNKPHKQLNNDVAMAHEEEHSVKEEMSDPLAALESALAAPYRPINDGMPEEKVSEKEAKAVVPVEALATSPAQIKQNPPAKKEATPPLSPSAIAKTLQPSPPKKQSSFPASLQRTNSAFHSLDFSRRLSLVDAKYQDGRFAARIEKTEDDESAVNPGRLKSLKDLPLLNKLRYAVASASTAKSTEALSLARAVSDDSASDSESETSDMSEGSPEDPVDTHPLPYLGRLIIPAKRKLPTEGHGTPLSVTSFAESLAGDWQDSNSLLLDESSLTFFEPNTWDWSIPDLSMEPPEEKPLNGKESIAVTQILTDQIVSATLDLLDENALVESTSSIEPSSETRWQICIKELFPKAAECTLSALIAIHDVFPDLSAQAKGQQRPPPRKPNESNAIPSNHMYPMNPPFIRVRRAETHWDLLPPSIAFWEPLGLAPASPPKNVVAFCIYPHSASLRPILDRFMLNLQLAYDTCKLGSHARVETVIEYEGGLVPVKANSQTSAKEAFRALKDTCIQLGKLLAIQYAQLGEQQDTKIDAFVVYMVDPFGNPAALWELCSAFWSLFQAYGQGPPGRSDPTPKPDLVLQIIPIKYLASFDVPVILDAATYVSLAREVYDRCPPSVASTDKTPLSIYKAPAFQLEESLPRNVQFKLLSEPPQDLLRENSYMHIAYAISLDGNWLTAAWSDSCGKSQAVVSYHLGTRVFGDIAKEIWQTTIEILQARRVQWRVCIAKSGPLDREELETWVLLITCPTQVNLFLTILTVIEDPPYKFTPTTPAPSNSSAQANTNTPGSTPQTGVSPDPTIGLTPAATPSADPAPDPAADPEARLIDVTDETWGIILAHRLHNSNSTNQFSPALISGLLVKRGITHATSNSIHHPIPDPLPGPITVAVNILWIGAVGSTWKRAAESRGTQY

Gene
SSN2
Protein
Mediator of RNA polymerase II transcription subunit 13
Organism
Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)
Length
1357 amino acids
Function
Component of the SRB8-11 complex. The SRB8-11 complex is a regulatory module of the Mediator complex which is itself involved in regulation of basal and activated RNA polymerase II-dependent transcription. The SRB8-11 complex may be involved in the transcriptional repression of a subset of genes regulated by Mediator. It may inhibit the association of the Mediator complex with RNA polymerase II to form the holoenzyme complex (By similarity).
Similarity
Belongs to the Mediator complex subunit 13 family.
Mass
153.091 kDa
Sequence
MDILETSFRLEDVLSSYYRVEKVVRVNYQQFVPRTPDDQWCIQSELLIRKKDPKALVALFSRELWCFSINDQDLPMPGLEGIGEPPNSEKKGHFTPGFSKPNLPTPYAIFLKALRRMIHINMCLRSQNRLVPFGNTCIFQRDEKASSVIHFDSHLFENGDLTVSLCTKDMGFERLLSGAFTGRQVKRALYLAPSGIRAYLPFPDISKCLVAPPKNAHLLLVTLLVSHGIDLTQAKDLKWIKLVPNINHLNGYTPTISRYAEESQTSKSVIWPMDLCFQQTPADACVNTTRATPLDIGLQDSFDLIEDFIQLKLTSAYRIPGTSVNANTATGNNPLSTGGGFTDQFQPFVKHTNSSSCNYGPASRTKLTPSKAQDLRRSAAPLSADSFGNGFMTTPNVNENMGSVIDDMVICPSSVKSQNDLWNDRKSSNDDIDSINPTSQQGDSARITSGSEEQDVEVTFDKDLFGDEDDESDLFGDSSNKSTHRKEVREITDEMFDSAEIESDPEGKITPTGTSINYSTQQQTPLKRKYLDIPLDEITLPAAPLYTDPGAPLPVETPRDRRKSVFAPLNFNPMIESNVDNKYKNGGKFSFDPNEIDEPLKFEVSTTNISSSEEDDSEFSGDDFDELQQNNLQDIRAMEVGSSLQQYDMGRPINEFLNQSDSAKEDYLLPAYQSGDVIDVDKFPSRESHLDQIWKSPEINREDTPHRIGLPIIKPQLDGSGNLDIDNQITDNCSSNYYEPTPVVGADEKIQERTLHKDKKLDQQGDSAMASVVGDYSLAIKETRESSNGLPFLLRHMPLFSIPDVFLSKNPIVKVDSKLEDFLEILCEQLVFDQGFLGNFDVDPPTYKDVKLNEKGVIRETLNSVFSEFERLRGNEIISDMFYIKQPSVCVKKHGNLIKLKSDAESFAPLLHLKPSRGMKSFRGLFLTTILTQTCVSFITELAHIYSAQELGFCELVKLTNDEHNGLIVLNNFNTDTLLLLSAQIVSYCSTNMNNVKNIPLMIFLPVAPSSLEATITMTSKFQLIKNEVKSRLPDVELLLKLIPFDLTKDPVIMIDRYYELCRGIYNLLPPRTVKFASIADNLPEQVEFRTSAGNQNQLSHYDSYIHLAYTRSIDREWLAAAWSDSKGTENMVKAWYLGNSKARFETACNELWKLTVELASRKYGRICLILTRMDSVLPDDELMHWRRLSVTTRNLHLAVVCVGASTKVSLYDEDQFYPSFKPLFKDKRYANKIQANQLDDYEVVNIDEELHGVVFSSPLQLANSQHRCAIKSGALVRFKRCAGGDTLDKFEVNLLNCPHSDSTKLLKTILHQFRDIASLNTWFCISRGKDNYIPWHVVAVKKIMRFIIHVNGIEEK

Gene
SSN2
Protein
Mediator of RNA polymerase II transcription subunit 13
Organism
Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65)
Length
1345 amino acids
Function
Component of the SRB8-11 complex. The SRB8-11 complex is a regulatory module of the Mediator complex which is itself involved in regulation of basal and activated RNA polymerase II-dependent transcription. The SRB8-11 complex may be involved in the transcriptional repression of a subset of genes regulated by Mediator. It may inhibit the association of the Mediator complex with RNA polymerase II to form the holoenzyme complex (By similarity).
Similarity
Belongs to the Mediator complex subunit 13 family.
Mass
151.209 kDa
Sequence
MKEATDDYDLSKLVSNFYRLEKITKINYAQYLPKKQNDQWGIQMEIQMRKKDRKLLVALLSKELWCFSINDQVLPSPNDIDPELNVSADKTGSFTADYSKPNLPPHYALFLKSLKRMIYLNLVEQSKNTLVQFGNSCINITKNNESNNLLQIEPHLFSNSELAISICVKDLGLLPLKVNSIDPAFLSSHALYMAPSGVRVYLVENKNDNSGTNQEHLHKYLVPVPENGEVLLKTLYASHGIKLNSSTCQWVNIIPNITHLNGRAPNISQYMDLPKELRTIVWPLDLVFAQPALDIDSSTTLSQINGLDTFEDTLSLIDNFLQLKQSSSYRTPGSSGGLTGTNIGTNVFSSEGAYTDQFQVYPKSQTNQQQTSSNSKVSPSDAASPYPGIDKIIEQKQFTPDFMASPSVSGNSNELFNDRKNGHTDLLISPSKMDVDTDFPGSNLAGQEAPSQPASDVKKSSVSASDSELFGEEDEDEDDADLFGESNNDSTGESNANNSKGEITEDIFASSDDESSLQPKKESTFYDGIKNGSAESGLNMQDRANLKRTYLDIRIEETPLSSPLYTDPGAPLPVETPRDRRKSVFAPLNFNPIIAKDVDNKYKNGGKYSFSPLQKEEALNFDVSRTELSSSEGEDSESSDDELEDLANKNDGVVYDKAENIGYKTFANLQDSVPPGLIKQDFLGNPYLASLEGSKEGQNTIWKMPQTDIAQTESPLKAIDTSIGPDGTLPNTTSSEQSKSVYVHDYGISPTKMSNDPAFDTAKIEGKYEFMNNFPSSFPFLLRHMPLSLIPDTFKHLNPTITVNERNNQIIDLLAEQIVYDYNILGNLTIPDVPYSGIRNYSNGVVKNTIDNLFSEFTRLDGTTLISRLYPMETPFVSVRKQHDQIKLRSDVQQFTKYANLKPVRGIKNFKFLVLTDSFKEDCIQFISSLSQTYINHELGFCEHLQLTNEDSKGLIYLKDFEDSKLLLLAAQIVSYLSTNRTSGKEVAFMMIIPVQRCDISELVEKTAKFQIIQNEVKAKIPSMELYLKIVPMDFIKSPLTSVDDYTNLCISIYNILPNKMIKFTHIRKQIPEKLTFKTSQQASAFKYDAYIHLAYSRSVDKQWMFAALSDSAGKENMMKTWYLGSSKNKFDEACNHIWEMALSLAGKNYGKVCLILTRLNGILPDDELMNWRRLSGRNIHLAVVCVDDNTKISFFDRNESYPSYKRLYQNANSIETLVDPERIDDYLIRDLDQDIHGVIFENPFPLVNSLHRCAIKSGALVKFNVSTTATEPHSLDKFEVNLLNCPHSDSFKLLETILEEFRNLAALNVWFGITNGENGHIPWHVLAVKKMMKTLVHTRVKVAQ

Gene
SSN2
Protein
Mediator of RNA polymerase II transcription subunit 13
Organism
Yarrowia lipolytica (strain CLIB 122 / E 150)
Length
1324 amino acids
Function
Component of the SRB8-11 complex. The SRB8-11 complex is a regulatory module of the Mediator complex which is itself involved in regulation of basal and activated RNA polymerase II-dependent transcription. The SRB8-11 complex may be involved in the transcriptional repression of a subset of genes regulated by Mediator. It may inhibit the association of the Mediator complex with RNA polymerase II to form the holoenzyme complex (By similarity).
Similarity
Belongs to the Mediator complex subunit 13 family.
Mass
143.232 kDa
Sequence
MHRPRSSWPNLVWDHSFPHHVLTQGKYTTIPYRTYICLQGNETSLKEAEWAIRNDNPRALVKSYNKELWTFTLQEGVTPPSALDRFQLTETTTGVFLPSTTTPSSLTMTKQLTPPGYVALMLAIEAMIQEALKRDDHYVPFGNNLILPVTGDLLHLDARLTPGGDLLLQMYQQETEWEMFGKRKRDVANEIVGTKVVVAPTLVEGVVENSTNQIPDNLPVLLEMLDCLCSVRLRAKKQWTAVRIDTEVLLWPTELLFVDRKSATGKLEDEGKDALLWTEDILDSVFEATQLIRRGESGVNTNESTAAQPQPAQNGTNSMAPAAGTTNATTQRNEENKQIYPTPPEAPKRILPGILLERATAPAGGWGELDEELFGGDEVTEADFNFFDDMGGDKNDTDGDNDNGNDNDNDKADAMDVDVKEEAKKEEMIKKETKEEVPVKEEVQEEEPDESATTAALLTNNPAEEKAVVHGVNDSSTVNGAVDAAVSATVVSSVPYLPSDFDQLIVNPAEQRTFALVEFNREAEQRLNDKYAAGGRFFVPDDSSSDNEGSSDNTGDSSDSGDGSESVPRDVKRQKVDEGTLSDQTDEPEIDAKQLHQQWSAILNYNHDDKPAKKIDSSNDTTNSDGNSNNSNYEEAVQRLAEQVVWDNSCYKGLVPQENYYRPPSARFVKVVEQVFGDTSKRLSLIDFAKMSDKGGQQQPGVGMPINAAAGTAGGGPGTPVTVSNASGVPSGSSGAQASQMGALAVGSALSPSRGATPQPEGSSPETRPSNWTPGITSQVNSAASSPVPLQQHQQQQQSFSPMSPQTPAQAPVPSANSFANAANAAPTQRLATPMYSFMRGGSLIKAQPPILRFWSTFGLSPRNGPKPLTLTLIYPSGTAIGDAAAAFLISFKMCYEGCGFGLVTLGGSNGTGVVSSDYKNLDVSREGVLLVSNPYNDVLGFLNLAKAAAAGSKTATSTSTILTLPCSIFASYTALRAPSAMLLAALCRNLYDHLPPTSTKRRYGSVIQRQAPACVISKPVPPFINFKLLANTPDSVINEDSLLHVAYAASNRWITCAWSDQWGELAKVKVFCLQSESGPLRTLEEVCTEIWETTLQLNGSTDVRSVAVAKLGGMLDDELAMWLRVSSVTRGRRITPFFLVVDNRPSMVVTGSDDGSKGGNVAGGPAPAPPTGAAGAASTGSAPMSTPFRDTDSPDIYNHVTTPSVGEDKIDYDDMSIVDVHDEIHSVTLNHRQPLTMHSTRLGLATGYLVKTSPLNPNQLLVFSLTFVNCPCVVMHVAMKHFLRQYRNLISLAATTGVCDPEYAIVPWHVEAVDKMMRLVEEL