ssl-1

Helicase ssl-1

2395 amino acids

Probable catalytic component of a chromatin-remodeling complex which mediates the ATP-dependent exchange of histone H2A variant H2AV/htz-1 for H2A, leading to transcriptional regulation of selected genes by chromatin remodeling. Involved in foregut development, and may be involved in vulval development.

Belongs to the SNF2/RAD54 helicase family. SWR1 subfamily.

268.727 kDa

MPATPVRASSTRISRRTSSRSVADDQPSTSSAVAPPPSPIAIETDEDAVVEEEKKKKKTSDDLEIITPRTPVDRRIPYICSILLTENRSIRDKLVLSSGPVRQEDHEEQIARAQRIQPVVDQIQRVEQIILNGSVEDILKDPRFAVMADLTKEPPPTPAPPPPIQKTMQPIEVKIEDSEGSNTAQPSVLPSCGGGETNVERAAKREAHVLARIAELRKNGLWSNSRLPKCVEPERNKTHWDYLLEEVKWMAVDFRTETNTKRKIAKVIAHAIAKQHRDKQIEIERAAEREIKEKRKMCAGIAKMVRDFWSSTDKVVDIRAKEVLESRLRKARNKHLMFVIGQVDEMSNIVQEGLVSSSKSPSIASDRDDKDEEFKAPGSDSESDDEQTIANAEKSQKKEDVRQEVDALQNEATVDMDDFLYTLPPEYLKAYGLTQEDLEEMKREKLEEQKARKEACGDNEEKMEIDESPSSDAQKPSTSSSDLTAEQLQDPTAEDGNGDGHGVLENVDYVKLNSQDSDERQQELANIAEEALKFQPKGYTLETTQVKTPVPFLIRGQLREYQMVGLDWMVTLYEKNLNGILADEMGLGKTIQTISLLAHMACSESIWGPHLIVVPTSVILNWEMEFKKWCPALKILTYFGTAKERAEKRKGWMKPNCFHVCITSYKTVTQDIRAFKQRAWQYLILDEAQNIKNWKSQRWQALLNVRARRRLLLTGTPLQNSLMELWSLMHFLMPTIFSSHDDFKDWFSNPLTGMMEGNMEFNAPLIGRLHKVLRPFILRRLKKEVEKQLPEKTEHIVNCSLSKRQRYLYDDFMSRRSTKENLKSGNMMSVLNIVMQLRKCCNHPNLFEPRPVVAPFVVEKLQLDVPARLFEISQQDPSSSSASQIPEIFNLSKIGYQSSVRSAKPLIEELEAMSTYPEPRAPEVGGFRFNRTAFVAKNPHTEESEDEGVMRSRVLPKPINGTAQPLQNGNSIPQNAPNRPQTSCIRSKTVVNTVPLTISTDRSGFHFNMANVGRGVVRLDDSARMSPPLKRQKLTGTATNWSDYVPRHVVEKMEESRKNQLEIVRRRFEMIRAPIIPLEMVALVREEIIAEFPRLAVEEDEVVQERLLEYCELLVQRFGMYVEPVLTDAWQCRPSSSGLPSYIRNNLSNIELNSRSLLLNTSTNFDTRMSISRALQFPELRLIEYDCGKLQTLAVLLRQLYLYKHRCLIFTQMSKMLDVLQTFLSHHGYQYFRLDGTTGVEQRQAMMERFNADPKVFCFILSTRSGGVGVNLTGADTVIFYDSDWNPTMDAQAQDRCHRIGQTRNVSIYRLISERTIEENILRKATQKRRLGELAIDEAGFTPEFFKQSDSIRDLFDGENVEVTAVADVATTMSEKEMEVAMAKCEDEADVNAAKIAVAEANVDNAEFDEKSLPPMSNLQGDEEADEKYMELIQQLKPIERYAINFLETQYKPEFEEECKEAEALIDQKREEWDKNLNDTAVIDLDDSDSLLLNDPSTSADFYQSSSLLDEIKFYDELDDIMPIWLPPSPPDSDADFDLRMEDDCLDLMYEIEQMNEARLPQVCHEMRRPLAEKQQKQNTLNAFNDILSAKEKESVYDAVNKCLQMPQSEAITAESAASPAYTEHSSFSMDDTSQDAKIEPSLTENQQPTTTATTTTTVPQQQQQQQQQKSSKKKRNDNRTAQNRTAENGVKRATTPPPSWREEPDYDGAEWNIVEDYALLQAVQVEFANAHLVEKSANEGMVLNWEFVSNAVNKQTRFFRSARQCSIRYQMFVRPKELGQLVASDPISKKTMKVDLSHTELSHLRKGRMTTESQYAHDYGILTDKKHVNRFKSVRVAATRRPVQFWRGPKALESRNLQSLNGGMPPRHESRLAEFDVKTNIRLDAEDIVTMSDESIVAYEASKKKLLASRQTKPSPRQDVRFHTLVLRPYTVPVTTEYSAAPSRREMRIAVPPLQPSALSTISSVAAAATSGPLPSIQHLQSSSTGLGSQQNLQNSHNSEQRNNVQNMHQNQYNSSQNPPIPIRQIGAASSHQHDQGSQGPGGKPQAYHLVQQGSQQQQQQQQQATLQRRNAAAAAGSNVQFIQQQQQQQQSGKNCGQGQSFVVMGSQSSSNDGQGGASTVGGGGGGSQQPHQQQQQQPQQRIQYIPQVTGSGNNGGGGGRGGYGSTLVMPRGGRVVRPAGTLPGGGRLYVDHNRHPYPMSSNVVPVRVLPATQQGQQRMMTGQRRPAPAPGTVAAMVLPNRGAGGIPQMRSLQRGSYTGGGGQQRINVMVQPQQMRSNNGGGVGGQGGLQGGPGGPQGIRRPLVGRPLQRGVDNQAPTVAQVVVAPPQGMQQASQGPPVLHMQRAVSMQMPTSHHHQGQQQAPPQSSQQASQQAPTSDSGTSAPPRQAPPPQN

SSL-1

Presqualene diphosphate synthase

403 amino acids

Catalyzes the biosynthesis of presqualene diphosphate (PSPP). Works in combination with SSL-2 or SSL-3 to produce respectively squalene or botryococcene. In most other species, farnesyl diphosphate (FPP) is converted into squalene in a two-step reaction by a single enzyme.

Belongs to the phytoene/squalene synthase family.

45.953 kDa

MTMHQDHGVMKDLVKHPNEFPYLLQLAATTYGSPAAPIPKEPDRAFCYNTLHTVSKGFPRFVMRLPQELQDPICIFYLLLRALDTVEDDMNLKSETKISLLRVFHEHCSDRNWSMKSDYGIYADLMERFPLVVSVLEKLPPATQQTFRENVKYMGNGMADFIDKQILTVDEYDLYCHYVAGSCGIAVTKVIVQFNLATPEADSYDFSNSLGLLLQKANIITDYNEDINEEPRPRMFWPQEIWGKYAEKLADFNEPENIDTAVKCLNHMVTDAMRHIEPSLKGMVYFTDKTVFRALALLLVTAFGHLSTLYNNPNVFKEKVRQRKGRIARLVMSSRNVPGLFRTCLKLANNFESRCKQETANDPTVAMTIKRLQSIQATCRDGLAKYDTPSGLKSFCAAPTPTK