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SS1G_05513

Gene
SS1G_05513
Protein
Leucine aminopeptidase 2
Organism
Sclerotinia sclerotiorum (strain ATCC 18683 / 1980 / Ss-1)
Length
608 amino acids
Function
Aminopeptidase that preferentially cleaves di- and tripeptides. Also has low epoxide hydrolase activity (in vitro). Can hydrolyze the epoxide leukotriene LTA(4) but it forms preferentially 5,6-dihydroxy-7,9,11,14-eicosatetraenoic acid rather than the cytokine leukotriene B(4) as the product compared to the homologous mammalian enzyme (in vitro).
Similarity
Belongs to the peptidase M1 family.
Mass
68.945 kDa
Sequence
MPRDPNTLSNYNNWRTKHTIADLAIDFKKQRVHGTVTLQLESITDKESEEIILDTSFVDVQKIAVDGSKTEEWVLKERNEPYGSPLSVKIPGGAAKGTIIALDITISTTDKCTALQWLTPAQTSNKKFPYMFSQCQAIHNRSIFPCQDTPDVKSTYDFRIRSPLPVLASGLPRGAASFVHGENGESGTLLYSFYQEIPMPSYLFALSSGDIATASIGSRSLVSTGPEELLGAKWELERDTEKFIETIEKIVYPYEWTQYNVLVLPPSFPYGGMENPVFTFATPTIISGDRENVDVIAHELAHSWSGNLVSNASWEHFWLNEGWTVYLERRIIAAVHGEAYRDFSSIIGWKALEDSVKLFGEDHEFTKLVVDLKGKDPDDAFSSVPYEKGFHFLYYLERLVGKPTWDKFIPHYFTTWKKKSLDSYEFKATLLDFFASDEAASKALESVDWDSWFYKPGLPPKPEFDTSLVDKCYALAKKWESKDFVPSPSDIEGWSANQVVVFLQQVQLFTTPLTPSQSQAMGKAYSLVDTQNVELSSRYFGVGLAAKDESVYLPTAELLGKVGRMKFVRTLYRKLLVVDRKLAEETFEKNKDFYHPICREQVEKDLKE