About Products Protein Database Contact

SRS2

Gene
SRS2
Protein
ATP-dependent DNA helicase SRS2
Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
Length
1174 amino acids
Function
ATP-dependent DNA helicase involved in DNA repair at least for UV-induced lesions. The polarity of the helicase activity was determined to be 3' to 5'.
Similarity
Belongs to the helicase family. UvrD subfamily.
Mass
134.306 kDa
Sequence
MSSNNDLWLHLVSQLNTQQRAAALFDYTRGLQVIAGPGTGKTKVLTSRVAYLILHHHIHPRDIIVTTFTNKAANEMKERLQEMLRGAGVNISELLIGTFHSICLKILYRFGHLVDLQKDWRIIDEKEIDVILDDMIEKVPDQIRDYASSITRKVNLCMPSKNGDEWTIHPKLIKKQISKLKSNAILPEEYILDSNHDAALGYFYQIYQSELSKKNTLDFDDLLMYTFRLLTRVRVLSNIKHVLVDEFQDTNGIQLDLMFLFAKGNHHLSRGMTIVGDPDQSIYAFRNALAHNFLEMGRKCPIEYSTIILVENYRSSQKILNTSEILITQQNKGRQNRAPLRAQFDLDFPPVYMNFPAYFLEAPSLVRELLYLKALPNLFTFNDFAILVRQRRQIKRIESALIEHRIPYKIIRGHSFWDSKETRAMLNLLKLIFSPNDKHAILASLLYPARGLGPATGEKIKNALDTLATDVSCFQILKDISSKKIMLDIPTKGRSVIADFISMIENCQLLLQSTLLGGLSDLFDKLYELSGLKYEYLYKDGKKKNDQLEKSEPNLLNARHKNIELLKNYFLALLSKSESSDKEKNEAIKAATDEAEPIENKVITPKEYLRNFFNSLSLHSDAAEEEESESNKDAKIKREKNGFVTISTIHGAKGLEWPVVFIPGCEEGIIPCVFNDDKKDESEEDEEEDQENSKKDASPKKTRVLSVEDSIDEERRMFFVAQTRAKYLLYLSNTVTVEDVDRPRIASRFLTTDLIKAMSDSQKLFESTNSIKKLYRILNKKPPAEDDKLFSLDQLRKDYNQFIENRRERMIWQGIQMNDVYGIQLSRNKLLGSVSDFTSAADQLRLETQNSIFPQKKLIEKSRPSKINGNYAPKSRVKSPEKRYAPETTSFHSPTKKKVYAPQYVSTTNVPSRQEFHSSTGKNIPFLRREDRSITDISPRSSTRSLKGASPNKTSHMSDDLMRPSPTRKDKVTRNIHFATAGTFRIETQSNVDELHPPEYSNKSGQSLTSSEFSGFSSACSNSDQPTNLIEDINNELDLSDEELLNDISIERRRELLGSKKTKKIKPKTRNRKSKRGDKVKVEEVIDLKSEFEEDDSRNTTAAELLHNPDDTTVDNRPIISNAKFLADAAMKKTQKFSKKVKNEPASSQMDIFSQLSRAKKKSKLNNGEIIVID

Gene
SRS2
Protein
ATP-dependent DNA helicase SRS2-like protein At4g25120
Organism
Arabidopsis thaliana
Length
1147 amino acids
Function
ATP-dependent 3'- to 5'-DNA helicase that could disrupt recombinogenic DNA intermediates and facilitate single strand annealing. Unwinds nicked and partial Holliday junctions in vitro. Anneals two single strands into a dsDNA molecule in vitro.
Similarity
Belongs to the helicase family. UvrD subfamily.
Mass
129.43 kDa
Sequence
MENLPPNRGMWNQEYSHGRISQSFRSAKPLLDRKRPIENAPNSSNPLPQRMKESMDTESVSHNINFNSTPLMELSANTPYKRLKPEIESYADGHPCGLRTPPPRFDLDKEIINGFQTDIYADVGSLSEAFVTPLKEPERVTLSNGCSTSSILDDDFDDSILEEIDLICEQSARKAACQTPTTSIYQTPSKDNKSSDPKASLDFRDVEKFEPDSNVKLKLDEETPTIAADPALLNSMPDECSKYMLSLNDRQRDAACSNISTPLMVIAGPGSGKTSTMVGRVLVLLNEGLLPSNILAMTFTKAATSEMRERIGKSAGKKAAKDITISTFHSFSLQLCRMHADKLQRTSEFSVYGHGQQRRAIIEAVRLYEEEKKNGSKTSVPCESGEGLNGAGAGAVCPEYAKDLSKKWQKFVTQGKASGKSPEQCRKMGNEIGAKILGNYNDILKACDALDYHDLISCSVTLLSDFPEVFKECQDTWKAIIVDEFQDTSTMQYKLLRMLGSHNHITIVGDDDQSIFGFNGADSSGFDSFRRDFPNYKEVRLIKNYRSSRHIVEAASSIIKNNTKRCQSKSISSENSQGSKITVKECHNEEAQCAYVIDKIIEITNDGSTPCCSHGDIAILYRRQVSGKVFQNAFRQRKIPFNVHGVAFYRKKVVQVILAMLKTTFSECDDASYRRVFKALLPFEKEEKKRIIEHIEKISTSRKCSFISAASDIFNAKISGTFKRSQLTQGRKVLQTLDMVAKLVDREQSLSAVVTCVANMIPQKYLLEQRAVVDNDGGKLLNEDNDLRSVLQYLMDDVAEFISTHCTTTEEEDAIKEKKGCNQLHSFINYISERETENFRSRRRDNENSVTLTTIHQSKGLEWDIVFIVKANENEIPLLHESNGNASESGTSLEEERRLLYVAMTRARKKLFFLYVTVDSNWQVLQPSRFLKEIPGHLLQGDMSVNDCRKVHENLPNKTEQSVSSFGTDIKHEESKLTDNDVMNIPEDYASEESIAAYALNGNNFLKRFDVEVRSVVSHLFHNWAKKQAFQEPKRLIDKVRFVIGERLAIKKNKHKDVLRALKSSLTSEEAFQYAEHVLRWEQLPADTRAHIVREKQEHFQKLRIENSMGTSEATSKQIAFLHSLGCTVVPTSRLHASRLIEQYKSL

Gene
srs2
Protein
ATP-dependent DNA helicase srs2
Organism
Schizosaccharomyces pombe (strain 972 / ATCC 24843)
Length
887 amino acids
Function
ATP-dependent DNA helicase involved in DNA repair at least for UV-induced lesions. Also aids the recombinational repair of camptothecin-induced collapsed replication forks.
Similarity
Belongs to the helicase family. UvrD subfamily.
Mass
101.124 kDa
Sequence
METKSSYLKFLNEEQRISVQSPHKYTQILAGPGSGKTRVLTARVAYLLQKNHIAAEDLIIATFTNKAANEIKLRIEAILGNSEASKLISGTFHSIAYKYLVKYGKHIGLSSNWLIADRNDTQAIMKRLLDSLKKAKNPIASGIRGQELTPQNALNRITKLKSNGLLVKPGMDQLSLINGLEEPPKELQSHQSVELYRLYQTSLWKNNLADFDDLLLNFILLLQKQPDCVRNIKHILIDEFQDTSKIQYFLVKLLALQNSDITIVGDPDQSIYGFRSAEIRNLNQMSEDFEGTQVLHLERNYRSAKPILELALSIISQDKSRPKKGLKSNHISSLKPHYRLFETNNKESYWIAREIKRIVGSCPELIFYNDIAILVRSSSLTRSLEHALSELGVPYRMVGVNKFFDREEIRDLIAYLRVLANKDSTSLIRVINVPPRNIGKTKIDRIIFESERRGLTFWQTLNEVKNENILLSQRNDKSFLKSLKSFLCSISKLENRYLSNGHSATLSDLLLGILSEIKYYEYLVRKNKETVEEKWENVMELVQQSDNISCIFYELDYKISTIVLLQNFLTQIALVNEEQKEGESQKVTISTLHAAKGLEWPVVFLPCLCENIIPHSRSDDLDEERRLLYVGATRAQALLYLSSFKSVTGMFADMQNSDNVQDVSPFLKGEEMKRWVMESEIVFNEKIASEIGTILGRKSYGKITNLSGIGSNANHNGTKFENLGFQCCRVLAEAELKKRERVKSVNDYNKDETNFRKHNAKRSKTDIRSWFEKKQPIDSDVEISEPSRSASIMVANKDLNDRSFETVNRIVSTRASTTNASFMSSVRQNLGRGPSTKDQVINRTLREGHQDVVQHTDLNQSNTKVASARPAGSRKRLGVRLRVSRML

Gene
SRS2
Protein
Protein SHI RELATED SEQUENCE 2
Organism
Arabidopsis thaliana
Length
322 amino acids
Function
Transcription activator that binds DNA on 5'-ACTCTAC-3' and promotes auxin homeostasis-regulating gene expression (e.g. YUC genes), as well as genes affecting stamen development, cell expansion and timing of flowering. Synergistically with other SHI-related proteins, regulates gynoecium, stamen and leaf development in a dose-dependent manner, controlling apical-basal patterning. Promotes style and stigma formation, and influence vascular development during gynoecium development. May also have a role in the formation and/or maintenance of the shoot apical meristem (SAM).
Similarity
Belongs to the SHI protein family.
Mass
34.144 kDa
Sequence
MAGIFSLGGNNNNNGDEEEENQQQQKTNWVWYRSNANTNNINPSSSQQVWQIPPEQMLMHHHSHPQQQSLDLYPGHQIDVSDLATSSRSITISCRDCGNQAKKDCTHMRCRTCCKSRGFDCSTHVRSTWIPVARRRERQQQLHMSTSGGGGGSGSGGAGGGGSSIPKRHRDPTLPGTSSSSRLPSHSAGLEMGEASFPGEVSSDALFRCVKMSGVDDGGDGQYAYQTTVNIGGHLFKGILYDQGPESSYMSGGSGGSDHQSSSAGGGGGGHPFNPPVVTDGGGGVSSAMFVDPNSGGYYSSNMTTSVFMPPGTQFYQNPPRS