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SRB7

Gene
SRB7
Protein
Mediator of RNA polymerase II transcription subunit 21
Organism
Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65)
Length
219 amino acids
Function
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).
Similarity
Belongs to the Mediator complex subunit 21 family.
Mass
24.565 kDa
Sequence
MTDRLTQLQRCLDQVMEQFCATLNFIDKRHDFEPFNDKEPKMTDKHASVATPEEFSNGIDELSTDIIVKIRQITTLIDSLPGVGVSAEEQLHKIDSLQKKLVDIEDEKIHAIKKKDDLLKQVDDLITVFVGGIADSRRGTSLAPENVQEDNDIKQEAEVPTSSEAIEQKIANEKIESKIEGEYNDNINEDSDSKSADSELFMDKDDADNISESISPGKI

Gene
srb7
Protein
Mediator of RNA polymerase II transcription subunit 21
Organism
Aspergillus oryzae (strain ATCC 42149 / RIB 40)
Length
208 amino acids
Function
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).
Similarity
Belongs to the Mediator complex subunit 21 family.
Mass
22.131 kDa
Sequence
MADILTQLQTCLDQLATQFYATIGYLVTYHDNSPAIPPQNDPTAAPALAKITKNSTAPPAPAGAPAGSQASPQQQSAQIPGQQQQGGGDAGQTPGAGGGTGGAGADPNLPPAPDSPRTFASRQRELARDLVIKEQQIEYLISVLPGIDSSEAEQERRIKELEKELRSAEEDREQRVRELRKLRKKLENVLGAVEVGIYGDRGAVASRR

Gene
srb7
Protein
Mediator of RNA polymerase II transcription subunit 21
Organism
Neosartorya fischeri (strain ATCC 1020 / DSM 3700 / CBS 544.65 / FGSC A1164 / JCM 1740 / NRRL 181 / WB 181)
Length
207 amino acids
Function
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).
Similarity
Belongs to the Mediator complex subunit 21 family.
Mass
22.321 kDa
Sequence
MADILTQLQTCLDQLATQFYATIGYLSTYHDNSPAIPHPDVPDAAPALAKIPKNSTAPPVPAGAPVPAQSQASPPAQNPAHGAAGAGTSVGEGGQTPGPAAGAGADPNLPAPDSPRTFASRQRELARDLIIKEQQIEYLISVLPGIDSSEAEQEKRIRELEGELRRVEEERELKMRELKRLRRTLENVLRAVETGLYGDRELLERYS

Gene
srb7
Protein
Mediator of RNA polymerase II transcription subunit 21
Organism
Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100)
Length
207 amino acids
Function
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).
Similarity
Belongs to the Mediator complex subunit 21 family.
Mass
22.153 kDa
Sequence
MADILTQLQTCLDQLATQFYATIGYLSTYHDNSPAIPPPDVPDAAPALAKIPKNSTAPPVPAGAPVPALSQASPPAQNPAHGAAGAGTSVGEGAQTPGPAAGAGADPNLPAPDSPRTFASRQRELARDLIIKEQQIEYLISVLPGIDSSEAEQEKRIRELEGELRQVEEERELKMRELKRLRRTLENVLTAVETGLYGDRELLEKYA

Gene
srb7
Protein
Mediator of RNA polymerase II transcription subunit 21
Organism
Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139)
Length
203 amino acids
Function
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).
Similarity
Belongs to the Mediator complex subunit 21 family.
Mass
21.626 kDa
Sequence
MADILTQLQTCLDQLATQFYATIGYLTTYHDNSPAIPPDNPTSAPALAKIQKNSTNPPIPAGAAAILNASQGSPSGAATGAVTPGPPAPNASAGSGAGEAGAARQEEGLPPRPDSPRTFTARQRELARDLVIKEQQIEYLISVLPGIGSSEAEQERRIRKLEEELRAVEEEREKRVRELRVLRRRVEEVLGAVEGGIYGGSSY

Gene
SRB7
Protein
Mediator of RNA polymerase II transcription subunit 21
Organism
Coccidioides immitis (strain RS)
Length
197 amino acids
Function
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).
Similarity
Belongs to the Mediator complex subunit 21 family.
Mass
21.274 kDa
Sequence
MADILTQLQTCLDQLATQFYATVAYLTTYHDHSPAIPPPSVPSAVPQLKKIPKNPPPAAPTSGTATNTPGAAGGPSGDTKDAAAGPSNAPQMQQQHQEQPPDAPPRPDSPNTFLMRQRELARDLIIKEQQIEYLISVLPGIKSSEAEQQERIKQLAEELRVVEEERSARRRELRRLGEKVDGLLGAVSRGTGISNSG

Gene
srb7
Protein
Mediator of RNA polymerase II transcription subunit 21
Organism
Aspergillus niger (strain CBS 513.88 / FGSC A1513)
Length
196 amino acids
Function
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).
Similarity
Belongs to the Mediator complex subunit 21 family.
Mass
21.37 kDa
Sequence
MADILTQLQTCLDQLATQFYATLCYLTTYHDNIPATPPPTSTTPSAAPLLAKIPKNASTPPVPASAPQAAQSQSQASPPPPDTANPQTGGQHADQQQQSPDGEGLPAPDSPATFAARQRELARDLVIKEQQIEYLISVLPGIDSSEAEQERRIRELEGELRIVEGVREERRRELGVLRRRLEGVLGVVERGIYSRD

Gene
srb7
Protein
Mediator of RNA polymerase II transcription subunit 21
Organism
Aspergillus clavatus (strain ATCC 1007 / CBS 513.65 / DSM 816 / NCTC 3887 / NRRL 1)
Length
189 amino acids
Function
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).
Similarity
Belongs to the Mediator complex subunit 21 family.
Mass
20.568 kDa
Sequence
MADILTQLQTCLDQLATQFYATIGYLSTYHDNSPATTPTNIPNAAPALAKIPKNSTAPPVPAGAPVPSQSSPPPPQTQRGASEAAADPNLPPAPDSPRTFASRQRELARDLIIKEQQIEYLISVLPGIDSSEAEQEKRIRELEAELRGVEEEREAKIRELRTLGRTLERVMGAVETGIYGDRAVLERDS

Gene
SRB7
Protein
Mediator of RNA polymerase II transcription subunit 21
Organism
Candida albicans (strain SC5314 / ATCC MYA-2876)
Length
178 amino acids
Function
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).
Similarity
Belongs to the Mediator complex subunit 21 family.
Mass
20.289 kDa
Sequence
MADRLTQLQICLDQLIQQFNSTINYVNTSAEPSLLDDDDVNSYSNMAANAPLPQSQQQRQQQKKQQEPQQEIEQPQQQSNPESKSISPPKEKVSFDNVINELCTDLILKSRQIKMLIDSLPGIGVTPNEQMNLINELSDKLQAIEEERIQKIKEKDNLLNLLESMIKEVVNGITETRI

Gene
SRB7
Protein
Mediator of RNA polymerase II transcription subunit 21
Organism
Debaryomyces hansenii (strain ATCC 36239 / CBS 767 / JCM 1990 / NBRC 0083 / IGC 2968)
Length
173 amino acids
Function
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).
Similarity
Belongs to the Mediator complex subunit 21 family.
Mass
18.786 kDa
Sequence
MTDRLTQLQVCLDQLVEQFNATVNYVNTNSEPGLLDEDPSSVSNLAANAPIPGVQQQPSQGSGGGSNKQTNAGNSVSNQPSAKAEAESNFENTINELSTDIILKSRQITMLIDSLPGIGVSPESQLNMVEDLAKQLEEVEKERIKKIEEKDKLLKWCESLIVEVATGISESRE

Gene
SRB7
Protein
Mediator of RNA polymerase II transcription subunit 21
Organism
Scheffersomyces stipitis (strain ATCC 58785 / CBS 6054 / NBRC 10063 / NRRL Y-11545)
Length
164 amino acids
Function
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).
Similarity
Belongs to the Mediator complex subunit 21 family.
Mass
17.987 kDa
Sequence
MADRLTQLQTCLDQLVEQFNATVNYINTSSEPSLLDEDPTSVSNIAASAPLPANQTQQGSTLGSNRQTVSPSTQAEAESNFENTINELSTDIILKSRQISMLIDSLPGIGVSPESQLKIIDDLSKELQSVEQEQVKKIQEKDKLLKWCESLIVEVATGISETRH

Gene
SRB7
Protein
Mediator of RNA polymerase II transcription subunit 21
Organism
Phaeosphaeria nodorum (strain SN15 / ATCC MYA-4574 / FGSC 10173)
Length
155 amino acids
Function
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).
Similarity
Belongs to the Mediator complex subunit 21 family.
Mass
17.476 kDa
Sequence
MSDKLTQIQDELDALLNMMQRQIAHIVLQAPPSVPPGQHRVDTMPEIKGKAASENPQSNPPQPAEPPVPEKISPEQFNQDLKEFSRDIVVKQQQVELLIASLPGLNVSEEQQVARMKELEKELEGLEDERAQAVREKEVLLKKVEDKIMSVGRSR

Gene
SRB7
Protein
Mediator of RNA polymerase II transcription subunit 21
Organism
Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37)
Length
143 amino acids
Function
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).
Similarity
Belongs to the Mediator complex subunit 21 family.
Mass
16.492 kDa
Sequence
MTDRLTQLQICLDQMMEQFCGAVNYVDKNHGFEPSNDSEEQMSDPQAHIVEEKEFEKNIDELTTDIILKTRQIMALIDSLPGVDVSAQEQLHRIDSLQKQLIKMEKEKIDAIKRKDALQEKVRTLTQDFTIGINESKTEARLV

Gene
SRB7
Protein
Mediator of RNA polymerase II transcription subunit 21
Organism
Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)
Length
142 amino acids
Function
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).
Similarity
Belongs to the Mediator complex subunit 21 family.
Mass
16.24 kDa
Sequence
MTDRLTQLQQCLDQIVEQFGSAITYVDRNHDFEPHNELEDKLSDPQATIAAAEDFDRNIDELTTDMILKTRQIIKLIDSLPGVDVSAEEQLSRIDSLQKKLIQVEGEKIEAIKRKESLTKDIEELINEFTEGIANSRRLNKA

Gene
SRB7
Protein
Mediator of RNA polymerase II transcription subunit 21
Organism
Yarrowia lipolytica (strain CLIB 122 / E 150)
Length
140 amino acids
Function
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).
Similarity
Belongs to the Mediator complex subunit 21 family.
Mass
16.15 kDa
Sequence
MADRLTQLQTCVDQMLTQYFSALTHINTNHGFKSLAGEELVKDDTVPVVTDEERERTLEELAKDLVVKSQQIDYLIDSLPGIGSSEEHQMQQIEKLQKELEHYDQVTEDVIKEKDELLEHCDELILKLAQRKAHIDVESM

Gene
SRB7
Protein
Mediator of RNA polymerase II transcription subunit 21
Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
Length
140 amino acids
Function
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. The Mediator complex, having a compact conformation in its free form, is recruited to promoters by direct interactions with regulatory proteins and serves for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. The Mediator complex unfolds to an extended conformation and partially surrounds RNA polymerase II, specifically interacting with the unphosphorylated form of the C-terminal domain (CTD) of RNA polymerase II. The Mediator complex dissociates from the RNA polymerase II holoenzyme and stays at the promoter when transcriptional elongation begins.
Similarity
Belongs to the Mediator complex subunit 21 family.
Mass
16.071 kDa
Sequence
MTDRLTQLQICLDQMTEQFCATLNYIDKNHGFERLTVNEPQMSDKHATVVPPEEFSNTIDELSTDIILKTRQINKLIDSLPGVDVSAEEQLRKIDMLQKKLVEVEDEKIEAIKKKEKLLRHVDSLIEDFVDGIANSKKST