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SP_0007

Gene
SPO0007
Protein
dITP/XTP pyrophosphatase
Organism
Ruegeria pomeroyi (strain ATCC 700808 / DSM 15171 / DSS-3)
Length
204 amino acids
Function
Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.
Similarity
Belongs to the HAM1 NTPase family.
Mass
22.106 kDa
Sequence
MTRAFDGDTLLIATHNKGKLEEMAHLLQPFGVKVVGAAEMNLPEPEETEDTFVGNARIKAHAAARATGLPALSDDSGITIDALDGAPGVYTADWAETGNGRDFLMAMTRAHDALEAKSAPHPRLAQFRCTLVLAWPDGHDEVFEGVAPGHLVWPIRGAAGFGYDPMFVPEGYDVTFAEMDRWEKNKISHRARAVEKFVKGCFGG

Gene
SP_0007
Protein
Uncharacterized protein SP_0007
Organism
Streptococcus pneumoniae serotype 4 (strain ATCC BAA-334 / TIGR4)
Length
88 amino acids
Mass
10.065 kDa
Sequence
MRLDKYLKVSRIIKRRTVAKEVADKGRIKVNGILAKSSTDLKVNDQVEIRFGNKLLLVKVLEMKDSTKKEDAAGMYEIISETRVEENV

Gene
spr0007
Protein
Uncharacterized protein spr0007
Organism
Streptococcus pneumoniae (strain ATCC BAA-255 / R6)
Length
88 amino acids
Mass
10.065 kDa
Sequence
MRLDKYLKVSRIIKRRTVAKEVADKGRIKVNGILAKSSTDLKVNDQVEIRFGNKLLLVKVLEMKDSTKKEDAAGMYEIISETRVEENV