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SPRR2A

Gene
SPRR2A
Protein
Small proline-rich protein 2A
Organism
Homo sapiens
Length
72 amino acids
Function
Cross-linked envelope protein of keratinocytes. It is a keratinocyte protein that first appears in the cell cytosol, but ultimately becomes cross-linked to membrane proteins by transglutaminase. All that results in the formation of an insoluble envelope beneath the plasma membrane.
Similarity
Belongs to the cornifin (SPRR) family.
Mass
7.965 kDa
Sequence
MSYQQQQCKQPCQPPPVCPTPKCPEPCPPPKCPEPCPPPKCPQPCPPQQCQQKYPPVTPSPPCQSKYPPKSK