About Products Protein Database Contact

SPINK1

Gene
Spink1
Protein
Serine protease inhibitor Kazal-type 1
Organism
Mus musculus
Length
80 amino acids
Function
In the male reproductive tract, binds to sperm heads where it modulates sperm capacitance by inhibiting calcium uptake and nitrogen oxide (NO) production (PubMed:9828198, PubMed:14645103, PubMed:16083722, PubMed:22228629).
Mass
8.488 kDa
Sequence
MKVAVIFLLSALALLSLAGNTFSAKVTGKEASCHDAVAGCPRIYDPVCGTDGITYANECVLCFENRKRIEPVLIRKGGPC

Gene
SPINK1
Protein
Serine protease inhibitor Kazal-type 1
Organism
Bos taurus
Length
79 amino acids
Function
In the male reproductive tract, binds to sperm heads where it modulates sperm capacitance by inhibiting calcium uptake and nitrogen oxide (NO) production.
Mass
8.467 kDa
Sequence
MKVASIFLLTALVLMSLSGNSGANILGREAKCTNEVNGCPRIYNPVCGTDGVTYSNECLLCMENKERQTPVLIQKSGPC

Gene
SPINK1
Protein
Serine protease inhibitor Kazal-type 1
Organism
Homo sapiens
Length
79 amino acids
Function
In the male reproductive tract, binds to sperm heads where it modulates sperm capacitance by inhibiting calcium uptake and nitrogen oxide (NO) production.
Mass
8.507 kDa
Sequence
MKVTGIFLLSALALLSLSGNTGADSLGREAKCYNELNGCTKIYDPVCGTDGNTYPNECVLCFENRKRQTSILIQKSGPC

Gene
Spink1
Protein
Serine protease inhibitor Kazal-type 1
Organism
Rattus norvegicus
Length
79 amino acids
Function
In the male reproductive tract, binds to sperm heads where it modulates sperm capacitance by inhibiting calcium uptake and nitrogen oxide (NO) production (By similarity).
Mass
8.528 kDa
Sequence
MKVAIIFLLSALALLSLAGNPPAEVNGKTPNCPKQIMGCPRIYDPVCGTNGITYPSECSLCFENRKFGTSIHIQRRGTC

Gene
SPINK1
Protein
Pancreatic secretory trypsin inhibitor
Organism
Struthio camelus
Length
69 amino acids
Function
This is a trypsin inhibitor, its physiological function is to prevent the trypsin-catalyzed premature activation of zymogens within the pancreas.
Mass
7.656 kDa
Sequence
EPDSAADTGTEAACSNYDLKKGCAKIFDPVCGTDNILYSNECLLCFQNLQRKTNVRIKRRGTCQEPSPR

Gene
SPINK1
Protein
Serine protease inhibitor Kazal-type 1
Organism
Canis lupus familiaris
Length
57 amino acids
Function
In the male reproductive tract, binds to sperm heads where it modulates sperm capacitance by inhibiting calcium uptake and nitrogen oxide (NO) production.
Mass
6.319 kDa
Sequence
NNMLQRQANCNLKVNGCNKIYNPICGSDGITYANECLLCLENKKRQTSILVEKSGPC

Gene
SPINK1
Protein
Serine protease inhibitor Kazal-type 1
Organism
Equus caballus
Length
56 amino acids
Function
In the male reproductive tract, binds to sperm heads where it modulates sperm capacitance by inhibiting calcium uptake and nitrogen oxide (NO) production.
Mass
6.093 kDa
Sequence
DSLGREAKCNNNAGGCTKIYNPVCGTDGNTYPNECMLCVENQKRQMPVLIQRSGPC

Gene
SPINK1
Protein
Serine protease inhibitor Kazal-type 1
Organism
Sus scrofa
Length
56 amino acids
Function
In the male reproductive tract, binds to sperm heads where it modulates sperm capacitance by inhibiting calcium uptake and nitrogen oxide (NO) production.
Mass
6.023 kDa
Sequence
TSPQREATCTSEVSGCPKIYNPVCGTDGITYSNECVLCSENKKRQTPVLIQKSGPC

Gene
SPINK1
Protein
Serine protease inhibitor Kazal-type 1
Organism
Ovis aries
Length
56 amino acids
Function
In the male reproductive tract, binds to sperm heads where it modulates sperm capacitance by inhibiting calcium uptake and nitrogen oxide (NO) production.
Mass
6.145 kDa
Sequence
NILGREAKCTNEVNGCPRIYNPVCGTDGVTYANECLLCMENKERQTPVLIQKSGPC

Gene
SPINK1
Protein
Serine protease inhibitor Kazal-type 1
Organism
Monodelphis domestica
Length
55 amino acids
Function
In the male reproductive tract, binds to sperm heads where it modulates sperm capacitance by inhibiting calcium uptake and nitrogen oxide (NO) production.
Mass
6.206 kDa
Sequence
DQGRDANCNYEFPGCPRNLEPVCGTDGNTYNNECLLCMENKKRDVPIRIQKDGPC