SOST

Gene

SOST

Protein

Sclerostin

Organism

Chlorocebus aethiops

Length

213 amino acids

Function

Negative regulator of bone growth that acts through inhibition of Wnt signaling and bone formation.

Similarity

Belongs to the sclerostin family.

Mass

23.908 kDa

Sequence

MQLPLALCLVCLLVHAAFRVVEGQGWQAFKNDATEIIPELGEYPEPPPELENNKTMNRAENGGRPPHHPFETKDVSEYSCRELHFTRYVTDGPCRSAKPVTELVCSGQCGPARLLPNAIGRGKWWRPSGPDFRCIPDRYRAQRVQLLCPGGAAPRARKVRLVASCKCKRLTRFHNQSELKDFGPEAARPQKGRKPRPRARGAKANQAELENAY

Protein

Sclerostin: SOST

Gene

SOST

Protein

Sclerostin

Organism

Homo sapiens

Length

213 amino acids

Function

Negative regulator of bone growth that acts through inhibition of Wnt signaling and bone formation.

Similarity

Belongs to the sclerostin family.

Mass

24.031 kDa

Sequence

MQLPLALCLVCLLVHTAFRVVEGQGWQAFKNDATEIIPELGEYPEPPPELENNKTMNRAENGGRPPHHPFETKDVSEYSCRELHFTRYVTDGPCRSAKPVTELVCSGQCGPARLLPNAIGRGKWWRPSGPDFRCIPDRYRAQRVQLLCPGGEAPRARKVRLVASCKCKRLTRFHNQSELKDFGTEAARPQKGRKPRPRARSAKANQAELENAY

Protein

Sclerostin: SOST

Gene

Sost

Protein

Sclerostin

Organism

Rattus norvegicus

Length

213 amino acids

Function

Negative regulator of bone growth that acts through inhibition of Wnt signaling and bone formation.

Similarity

Belongs to the sclerostin family.

Mass

23.974 kDa

Sequence

MQLSLAPCLACLLVHAAFVAVESQGWQAFKNDATEIIPGLREYPEPPQELENNQTMNRAENGGRPPHHPYDTKDVSEYSCRELHYTRFVTDGPCRSAKPVTELVCSGQCGPARLLPNAIGRVKWWRPNGPDFRCIPDRYRAQRVQLLCPGGAAPRSRKVRLVASCKCKRLTRFHNQSELKDFGPETARPQKGRKPRPRARGAKANQAELENAY

Protein

Sclerostin: Sost

Gene

SOST

Protein

Sclerostin

Organism

Bos taurus

Length

212 amino acids

Function

Negative regulator of bone growth that acts through inhibition of Wnt signaling and bone formation.

Similarity

Belongs to the sclerostin family.

Mass

23.777 kDa

Sequence

MQLSLALCLVCLLVHAAFRVVEGQGWQAFKNDATEIIPELGEYPEPLPELNNKTMNRAENGGRPPHHPFETKDASEYSCRELHFTRYVTDGPCRSAKPVTELVCSGQCGPARLLPNAIGRGKWWRPSGPDFRCIPDRYRAQRVQLLCPGGAAPRARKVRLVASCKCKRLTRFHNQSELKDFGPEAARPQTGRKLRPRARGTKASRAELENAY

Protein

Sclerostin: SOST

Gene

Sost

Protein

Sclerostin

Organism

Mus musculus

Length

211 amino acids

Function

Negative regulator of bone growth that acts through inhibition of Wnt signaling and bone formation.

Similarity

Belongs to the sclerostin family.

Mass

23.501 kDa

Sequence

MQPSLAPCLICLLVHAAFCAVEGQGWQAFRNDATEVIPGLGEYPEPPPENNQTMNRAENGGRPPHHPYDAKDVSEYSCRELHYTRFLTDGPCRSAKPVTELVCSGQCGPARLLPNAIGRVKWWRPNGPDFRCIPDRYRAQRVQLLCPGGAAPRSRKVRLVASCKCKRLTRFHNQSELKDFGPETARPQKGRKPRPGARGAKANQAELENAY

Protein

Sclerostin: Sost