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SNU13

Gene
SNU13
Protein
NHP2-like protein 1
Organism
Bos taurus
Length
128 amino acids
Function
Involved in pre-mRNA splicing as component of the spliceosome. Binds to the 5'-stem-loop of U4 snRNA and thereby contributes to spliceosome assembly. The protein undergoes a conformational change upon RNA-binding.
Similarity
Belongs to the eukaryotic ribosomal protein eL8 family.
Mass
14.174 kDa
Sequence
MTEADVNPKAYPLADAHLTKKLLDLVQQSCNYKQLRKGANEATKTLNRGISEFIVMAADAEPLEIILHLPLLCEDKNVPYVFVRSKQALGRACGVSRPVIACSVTIKEGSQLKQQIQSIQQSIERLLV

Gene
SNU13
Protein
NHP2-like protein 1
Organism
Homo sapiens
Length
128 amino acids
Function
Involved in pre-mRNA splicing as component of the spliceosome (PubMed:28781166). Binds to the 5'-stem-loop of U4 snRNA and thereby contributes to spliceosome assembly (PubMed:10545122, PubMed:17412961). The protein undergoes a conformational change upon RNA-binding (PubMed:17412961).
Similarity
Belongs to the eukaryotic ribosomal protein eL8 family.
Mass
14.174 kDa
Sequence
MTEADVNPKAYPLADAHLTKKLLDLVQQSCNYKQLRKGANEATKTLNRGISEFIVMAADAEPLEIILHLPLLCEDKNVPYVFVRSKQALGRACGVSRPVIACSVTIKEGSQLKQQIQSIQQSIERLLV

Gene
SNU13
Protein
NHP2-like protein 1
Organism
Macaca fascicularis
Length
128 amino acids
Function
Involved in pre-mRNA splicing as component of the spliceosome. Binds to the 5'-stem-loop of U4 snRNA and thereby contributes to spliceosome assembly. The protein undergoes a conformational change upon RNA-binding.
Similarity
Belongs to the eukaryotic ribosomal protein eL8 family.
Mass
14.174 kDa
Sequence
MTEADVNPKAYPLADAHLTKKLLDLVQQSCNYKQLRKGANEATKTLNRGISEFIVMAADAEPLEIILHLPLLCEDKNVPYVFVRSKQALGRACGVSRPVIACSVTIKEGSQLKQQIQSIQQSIERLLV

Gene
Snu13
Protein
NHP2-like protein 1
Organism
Mus musculus
Length
128 amino acids
Function
Involved in pre-mRNA splicing as component of the spliceosome. Binds to the 5'-stem-loop of U4 snRNA and thereby contributes to spliceosome assembly. The protein undergoes a conformational change upon RNA-binding.
Similarity
Belongs to the eukaryotic ribosomal protein eL8 family.
Mass
14.174 kDa
Sequence
MTEADVNPKAYPLADAHLTKKLLDLVQQSCNYKQLRKGANEATKTLNRGISEFIVMAADAEPLEIILHLPLLCEDKNVPYVFVRSKQALGRACGVSRPVIACSVTIKEGSQLKQQIQSIQQSIERLLV

Gene
Snu13
Protein
NHP2-like protein 1
Organism
Rattus norvegicus
Length
128 amino acids
Function
Involved in pre-mRNA splicing as component of the spliceosome. Binds to the 5'-stem-loop of U4 snRNA and thereby contributes to spliceosome assembly. The protein undergoes a conformational change upon RNA-binding.
Similarity
Belongs to the eukaryotic ribosomal protein eL8 family.
Mass
14.174 kDa
Sequence
MTEADVNPKAYPLADAHLTKKLLDLVQQSCNYKQLRKGANEATKTLNRGISEFIVMAADAEPLEIILHLPLLCEDKNVPYVFVRSKQALGRACGVSRPVIACSVTIKEGSQLKQQIQSIQQSIERLLV

Gene
snu13
Protein
NHP2-like protein 1
Organism
Xenopus laevis
Length
128 amino acids
Function
Involved in pre-mRNA splicing as component of the spliceosome. Binds to the 5'-stem-loop of U4 snRNA and thereby contributes to spliceosome assembly. The protein undergoes a conformational change upon RNA-binding.
Similarity
Belongs to the eukaryotic ribosomal protein eL8 family.
Mass
14.068 kDa
Sequence
MTEPEVNPKAYPLADAQLTKTLLDLVQQSANYKQLRKGANEATKTLNRGIAEFIVMAADAEPLEIILHLPLLCEDKNVPYVFVRSKQALGRACGVSRPVIACSVTIKEGSQLKPQIQSVQQAIERLLV

Gene
snu13
Protein
NHP2-like protein 1
Organism
Xenopus tropicalis
Length
128 amino acids
Function
Involved in pre-mRNA splicing as component of the spliceosome. Binds to the 5'-stem-loop of U4 snRNA and thereby contributes to spliceosome assembly. The protein undergoes a conformational change upon RNA-binding.
Similarity
Belongs to the eukaryotic ribosomal protein eL8 family.
Mass
14.066 kDa
Sequence
MTEPEVNPKAYPLADAQLTKTLLDLVQQAANYKQLRKGANEATKTLNRGIAEFIVMAADAEPLEIILHLPLLCEDKNVPYVFVRSKQALGRACGVSRPVIACAVTIKEGSQLKPQIQSLQQSIERLLV

Gene
SNU13
Protein
13 kDa ribonucleoprotein-associated protein
Organism
Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)
Length
127 amino acids
Function
Common component of the spliceosome and rRNA processing machinery. In association with the spliceosomal U4/U6.U5 tri-snRNP particle, required for splicing of pre-mRNA. In association with box C/D snoRNPs, required for processing of pre-ribosomal RNA (rRNA) and site-specific 2'-O-methylation of substrate RNAs. Essential for the accumulation and stability of U4 snRNA, U6 snRNA, and box C/D snoRNAs (By similarity).
Similarity
Belongs to the eukaryotic ribosomal protein eL8 family.
Mass
13.706 kDa
Sequence
MSSTPNPKAFPLADAALTQQILDVVQQASNMRQLKKGANEATKTLNRGISEFIIMAADCEPIEILLHLPLLCEDKNVPYVFVPSRVALGRACGVSRPVIAASITTNDASAIKSQIYAVKDKIETLLI

Gene
SNU13
Protein
13 kDa ribonucleoprotein-associated protein
Organism
Cryptococcus neoformans var. neoformans serotype D (strain B-3501A)
Length
127 amino acids
Function
Common component of the spliceosome and rRNA processing machinery. In association with the spliceosomal U4/U6.U5 tri-snRNP particle, required for splicing of pre-mRNA. In association with box C/D snoRNPs, required for processing of pre-ribosomal RNA (rRNA) and site-specific 2'-O-methylation of substrate RNAs. Essential for the accumulation and stability of U4 snRNA, U6 snRNA, and box C/D snoRNAs (By similarity).
Similarity
Belongs to the eukaryotic ribosomal protein eL8 family.
Mass
13.946 kDa
Sequence
MSAQPNPKAFPLANAQLTNQILDLIQQAQHYKQLKKGANEATKTLNRGICEFIVMTADVEPIEIVLHLPLLCEDKNVPYVFLPSKTALGRACGVSRPVIAASVTTNEARELNAQIQAVKNEIEKLLI

Gene
SNU13
Protein
13 kDa ribonucleoprotein-associated protein
Organism
Cryptococcus neoformans var. neoformans serotype D (strain JEC21 / ATCC MYA-565)
Length
127 amino acids
Function
Common component of the spliceosome and rRNA processing machinery. In association with the spliceosomal U4/U6.U5 tri-snRNP particle, required for splicing of pre-mRNA. In association with box C/D snoRNPs, required for processing of pre-ribosomal RNA (rRNA) and site-specific 2'-O-methylation of substrate RNAs. Essential for the accumulation and stability of U4 snRNA, U6 snRNA, and box C/D snoRNAs (By similarity).
Similarity
Belongs to the eukaryotic ribosomal protein eL8 family.
Mass
13.946 kDa
Sequence
MSAQPNPKAFPLANAQLTNQILDLIQQAQHYKQLKKGANEATKTLNRGICEFIVMTADVEPIEIVLHLPLLCEDKNVPYVFLPSKTALGRACGVSRPVIAASVTTNEARELNAQIQAVKNEIEKLLI

Gene
SNU13
Protein
13 kDa ribonucleoprotein-associated protein
Organism
Candida albicans (strain SC5314 / ATCC MYA-2876)
Length
126 amino acids
Function
Common component of the spliceosome and rRNA processing machinery. In association with the spliceosomal U4/U6.U5 tri-snRNP particle, required for splicing of pre-mRNA. In association with box C/D snoRNPs, required for processing of pre-ribosomal RNA (rRNA) and site-specific 2'-O-methylation of substrate RNAs. Essential for the accumulation and stability of U4 snRNA, U6 snRNA, and box C/D snoRNAs (By similarity).
Similarity
Belongs to the eukaryotic ribosomal protein eL8 family.
Mass
13.601 kDa
Sequence
MSAPNPKAFPLADSALTQQILDVVQQSQNLRQLKKGANEATKTLNRGISEFIIMAADTEPIEILLHLPLLCEDKNVPYVFVPSKAALGRACGVSRPVIAASVTSNDASSIKNQIYGIKDKIETLLI

Gene
SNU13
Protein
13 kDa ribonucleoprotein-associated protein
Organism
Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65)
Length
126 amino acids
Function
Common component of the spliceosome and rRNA processing machinery. In association with the spliceosomal U4/U6.U5 tri-snRNP particle, required for splicing of pre-mRNA. In association with box C/D snoRNPs, required for processing of pre-ribosomal RNA (rRNA) and site-specific 2'-O-methylation of substrate RNAs. Essential for the accumulation and stability of U4 snRNA, U6 snRNA, and box C/D snoRNAs (By similarity).
Similarity
Belongs to the eukaryotic ribosomal protein eL8 family.
Mass
13.683 kDa
Sequence
MSAPNPKAFPLADEKLSQQILDVVQQAANLRQLKKGANEATKTLNRGISEFIIMAADCEPIEILLHLPLLCEDKNVPYVFVPSRVALGRACGVSRPVIAASITTNDASAIKNQIYAVKDKIETLLI

Gene
SNU13
Protein
13 kDa ribonucleoprotein-associated protein
Organism
Debaryomyces hansenii (strain ATCC 36239 / CBS 767 / JCM 1990 / NBRC 0083 / IGC 2968)
Length
126 amino acids
Function
Common component of the spliceosome and rRNA processing machinery. In association with the spliceosomal U4/U6.U5 tri-snRNP particle, required for splicing of pre-mRNA. In association with box C/D snoRNPs, required for processing of pre-ribosomal RNA (rRNA) and site-specific 2'-O-methylation of substrate RNAs. Essential for the accumulation and stability of U4 snRNA, U6 snRNA, and box C/D snoRNAs (By similarity).
Similarity
Belongs to the eukaryotic ribosomal protein eL8 family.
Mass
13.661 kDa
Sequence
MSAPNPKAFPLADSALTQQILDVVQQSQNLRQLKKGANEATKTLNRGISEFIIMAADTEPIEILLHLPLLCEDKNVPYVFVPSKTALGRACGVSRPVIAASVTTNEASAMKNQIYGIKDKIETLLI

Gene
SNU13
Protein
13 kDa ribonucleoprotein-associated protein
Organism
Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37)
Length
126 amino acids
Function
Common component of the spliceosome and rRNA processing machinery. In association with the spliceosomal U4/U6.U5 tri-snRNP particle, required for splicing of pre-mRNA. In association with box C/D snoRNPs, required for processing of pre-ribosomal RNA (rRNA) and site-specific 2'-O-methylation of substrate RNAs. Essential for the accumulation and stability of U4 snRNA, U6 snRNA, and box C/D snoRNAs (By similarity).
Similarity
Belongs to the eukaryotic ribosomal protein eL8 family.
Mass
13.607 kDa
Sequence
MSAPNPKAFPLADATLSQQILDVVQQASNMRQLKKGANEATKTLNRGISEFIIMAADCEPIEILLHLPLLCEDKNVPYVFVPSRTALGRACGVSRPVIAASITTNDASAIKSQIYAVKDKIETLLI

Gene
SNU13
Protein
13 kDa ribonucleoprotein-associated protein
Organism
Ustilago maydis (strain 521 / FGSC 9021)
Length
126 amino acids
Function
Common component of the spliceosome and rRNA processing machinery. In association with the spliceosomal U4/U6.U5 tri-snRNP particle, required for splicing of pre-mRNA. In association with box C/D snoRNPs, required for processing of pre-ribosomal RNA (rRNA) and site-specific 2'-O-methylation of substrate RNAs. Essential for the accumulation and stability of U4 snRNA, U6 snRNA, and box C/D snoRNAs (By similarity).
Similarity
Belongs to the eukaryotic ribosomal protein eL8 family.
Mass
13.738 kDa
Sequence
MSAPNPKAFPLADATLTNQILDLIQQASHYKQLKKGANEATKTLNRGICEFIVMAADVEPIEIVLHLPLLCEDKNVPYVFVPSKTALGRACGVSRPVVSASVTTNEARELQSQIQTVKLAIERLLI

Gene
SNU13
Protein
13 kDa ribonucleoprotein-associated protein
Organism
Yarrowia lipolytica (strain CLIB 122 / E 150)
Length
126 amino acids
Function
Common component of the spliceosome and rRNA processing machinery. In association with the spliceosomal U4/U6.U5 tri-snRNP particle, required for splicing of pre-mRNA. In association with box C/D snoRNPs, required for processing of pre-ribosomal RNA (rRNA) and site-specific 2'-O-methylation of substrate RNAs. Essential for the accumulation and stability of U4 snRNA, U6 snRNA, and box C/D snoRNAs (By similarity).
Similarity
Belongs to the eukaryotic ribosomal protein eL8 family.
Mass
13.801 kDa
Sequence
MSEPNPKAFPLADAALTQQILDIVQQATHLRQLKKGANEATKTLNRGISEFIIMAADAEPIEILLHLPLLCEDKNVPYIFVPSKVALGRACGVSRPVISASVTSNDASQLKDQIIQMKDKIERLLI

Gene
SNU13
Protein
13 kDa ribonucleoprotein-associated protein
Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
Length
126 amino acids
Function
Common component of the spliceosome and rRNA processing machinery. In association with the spliceosomal U4/U6.U5 tri-snRNP particle, required for splicing of pre-mRNA. In association with box C/D snoRNPs, required for processing of pre-ribosomal RNA (rRNA) and site-specific 2'-O-methylation of substrate RNAs. Essential for the accumulation and stability of U4 snRNA, U6 snRNA, and box C/D snoRNAs.
Similarity
Belongs to the eukaryotic ribosomal protein eL8 family.
Mass
13.569 kDa
Sequence
MSAPNPKAFPLADAALTQQILDVVQQAANLRQLKKGANEATKTLNRGISEFIIMAADCEPIEILLHLPLLCEDKNVPYVFVPSRVALGRACGVSRPVIAASITTNDASAIKTQIYAVKDKIETLLI

Gene
snu13
Protein
13 kDa ribonucleoprotein-associated protein
Organism
Schizosaccharomyces pombe (strain 972 / ATCC 24843)
Length
125 amino acids
Function
Common component of the spliceosome and rRNA processing machinery. In association with the spliceosomal U4/U6.U5 tri-snRNP particle, required for splicing of pre-mRNA. In association with box C/D snoRNPs, required for processing of pre-ribosomal RNA (rRNA) and site-specific 2'-O-methylation of substrate RNAs. Essential for the accumulation and stability of U4 snRNA, U6 snRNA, and box C/D snoRNAs (By similarity).
Similarity
Belongs to the eukaryotic ribosomal protein eL8 family.
Mass
13.535 kDa
Sequence
MSVNPKAFPLADSGLTQQILDLVQQASHYKQLRKGANEATKTLNRGISEFIVMAADTEPIEILLHLPLLCEDKNVPYVFVPSKAALGRACGVSRPVISASITTNEASDLLPQIQAIKLAIEKLLI