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SNIP1

Gene
SNIP1
Protein
Smad nuclear-interacting protein 1
Organism
Homo sapiens
Length
396 amino acids
Function
Required for pre-mRNA splicing as component of the spliceosome (PubMed:29360106). Down-regulates NF-kappa-B signaling by competing with RELA for CREBBP/EP300 binding. Involved in the microRNA (miRNA) biogenesis. May be involved in cyclin-D1/CCND1 mRNA stability through the SNARP complex which associates with both the 3'end of the CCND1 gene and its mRNA.
Mass
45.778 kDa
Sequence
MKAVKSERERGSRRRHRDGDVVLPAGVVVKQERLSPEVAPPAHRRPDHSGGSPSPPTSEPARSGHRGNRARGVSRSPPKKKNKASGRRSKSPRSKRNRSPHHSTVKVKQEREDHPRRGREDRQHREPSEQEHRRARNSDRDRHRGHSHQRRTSNERPGSGQGQGRDRDTQNLQAQEEEREFYNARRREHRQRNDVGGGGSESQELVPRPGGNNKEKEVPAKEKPSFELSGALLEDTNTFRGVVIKYSEPPEARIPKKRWRLYPFKNDEVLPVMYIHRQSAYLLGRHRRIADIPIDHPSCSKQHAVFQYRLVEYTRADGTVGRRVKPYIIDLGSGNGTFLNNKRIEPQRYYELKEKDVLKFGFSSREYVLLHESSDTSEIDRKDDEDEEEEEEVSDS

Gene
Snip1
Protein
Smad nuclear interacting protein 1
Organism
Rattus norvegicus
Length
389 amino acids
Function
Required for pre-mRNA splicing as component of the spliceosome. Down-regulates NF-kappa-B signaling by competing with RELA for CREBBP/EP300 binding. Involved in the microRNA (miRNA) biogenesis. May be involved in cyclin-D1/CCND1 mRNA stability through the SNARP complex which associates with both the 3'end of the CCND1 gene and its mRNA.
Mass
44.923 kDa
Sequence
MKAGKSERERSSRRRHRSGDALATVVVKQERLSPEPVAHRRPDAPAASPPPPAAESGSAGHRGSRARGASRSPAKKKSKSSGRRSKSPRTKRSRSPHYSTVKVKQEREDHPRRGREDRQHRELSEQEHRRARNSERDRHRGHARQRRSSDERPVSGQGRDRDSQILQAQEEERDFNNARRREHRQQNESAGAEAQEVIPRPAGNKNKEVPVKEKPSFELSGALLEDTNTFRGVVIKYSEPPEARIPKKRWRLYPFKNDEVLPVMYIHRQSAYLLGRHRRIADIPIDHPSCSKQHAVFQYRLVEYTRADGTVGRRVKPYIIDLGSGNGTFLNNKRIEPQRYYELKEKDVLKFGFSSREYVLLHESSDTSELDRKEDEDEEEEEEMVSDSS

Gene
Snip1
Protein
Smad nuclear-interacting protein 1
Organism
Mus musculus
Length
383 amino acids
Function
Required for pre-mRNA splicing as component of the spliceosome. Down-regulates NF-kappa-B signaling by competing with RELA for CREBBP/EP300 binding. Involved in the microRNA (miRNA) biogenesis. May be involved in cyclin-D1/CCND1 mRNA stability through the SNARP complex which associates with both the 3'end of the CCND1 gene and its mRNA.
Mass
44.415 kDa
Sequence
MKAGKSERERSGRRRHRSGDALTTVVVKQERLSPEPVAHRRPDAPAASLSPPAAEPGHSGHRGSRARSPAKKKSKSSGRRSKSPRTKRSQSPHYPMVKVKQEREDHPRRGREDRQHREPSEQEHRRARNSERDRHRGHSRQGRSSDERPVSGQDRDRDSQNLQAQEEERDFHNARRREHRQQNESAGSEAQEVIPRPAGNRSKEVPVKEKPSFELSGALLEDTNTFRGVVIKYSEPPEARIPKKRWRLYPFKNDEVLPVMYIHRQSAYLLGRHRRIADIPIDHPSCSKQHAVFQYRLVEYTRADGTVGRRVKPYIIDLGSGNGTFLNNKRIEPQRYYELKEKDVLKFGFSSREYVLLHESSDTSELDRKEDEDDEEEEMVSDS