Protein
Structure-specific endonuclease subunit SLX4 1
Organism
Candida tropicalis (strain ATCC MYA-3404 / T1)
Function
Regulatory subunit of the SLX1-SLX4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA.
Similarity
Belongs to the SLX4 family.
Sequence
MSPEGEESHAEDNLYFHNTQMQSIHEETLAEESHAQSIQRSISRLSSFKHEDTDSESPIPVQKVIRHIKKTNTNTNTTKTKKRKLKVSKPRKNMSSSESVRQMYGSRKNGEQQGSIDGFLMSRFGDVDGCNESDRSSKLISQGEWESLSKFHEESNEKDKLLRKKIQRYYSEPQEELGEGCGMLSQASADPETKMTKEELESLYDLDSSTVFNQTTISAIGDMSEPTQVSEPCVVILSQTKVQSEASTQEDGADASVQEIKSSVPTQELFSTPEFVPAPLEQPVNKEVCSDQSIVVLEENVQSTQADDSDIVELISDSDPEPEEVSTKVQVLRSIYDSSGPVNDKQPSVASETVESDSTPIVSPVKTPQGTRMHVVQVASSNPSSPIKIVEENTEQQEEVFTDVESIYSTARTSFGTPKHTSPVILLESSDTDCDDNDNDVEPLSSMPMVKTVPKKRMRTTVLQVSAALKVQNYTDEKNNIKLRKIGDDIPVEVPTKDVEYEEIPDSQESVGGEGDNSVSIIEITREVHNNDYTGDESTDLFQVGLNKQDTCEDTSSPVVQIGGVENDILDSSLIEPVPEPESVPVPEEVQEQPQPTAIDKHTATQLREKFQLWGLKPVRGKEKMVEILQGISNFILPEHELLAVADKQELQSCIFMKLDAVIREGRAMYDRILSFEPIRIEELQMMLQSQDYYLELDVLRLYCDSSGITTTNA