sld2

DNA replication regulator sld2

569 amino acids

Has a role in the initiation of DNA replication. Required at S-phase checkpoint (By similarity).

Belongs to the SLD2 family.

62.156 kDa

MATVTVSEISNQAAILRAELKEWERGFAAANGGKKAERGDIKKVPEIAAKYKEYSRLKSQESASSSKNDKSHSKPTDTQERSKKRKHSSPNGPEQSQSHCQTTSTPRKSAAGIFQTPSKLKTTHPADVDPYDSPSVLRRLFSPSTHMQTSSPLKTAIGPTPQRDGKALGLFDLLSESGGSTATPTAARMASLKGIAAQTPSKKRKMDTIREEDEEEEDSPRVERTPASSGKKYMLSALFATPTAWKYSSIVDDGTSRGVIGNNDVTKQSPQATRNIDHANANLETPSFLRRSTSGLTGPDPTDMSPLPVRKPQQFVGKGLSQLVQGLRDMEEERLEDEWDVLREIEIEQTGTGVDVPNSQAADPNSTGRTFKKKGQKRTTRLVKMRPVVQAKPTTTRSQPQSLSQSEPRFEHNLVSAGGSGDVDELGIDDNDLVAVAETQADGPPSGRVGIPAAFIDDDLDSLRSISEAEQDSDSDPDYDADSKPLGRSKSFSEKMKEAIGATGQGSDTKQAQERQKVKAKEKKEKENIDTNAKKPSTRKINPQAHANYRSLKIRNRGGGRNFGRFRRR

sld2

DNA replication regulator sld2

535 amino acids

Has a role in the initiation of DNA replication. Required at S-phase checkpoint (By similarity).

Belongs to the SLD2 family.

58.919 kDa

MASVAISEIVTQSANLRAELKEWERAFAAQNGGRKAERKDIKKVPEIAAKYKEYSRLKALESSSPNPDDPKSVQLEERPKKRKRAFKDGPDAIQNSSTPRKTAKGALETPSKNRLSSSHPSQVDPYISPTALRRLFSPSTHRTPLKTAIGPTPQRDGKALGLFDLLSESGGSTATPSADRVASVRAANVRTPSKRKTMDTIMEEDEDGEEESPRLGRTPASSGKKWMLSALFATPTTLRYSAMVEDGNHITERNLGPPTDPEGTARDVAGPETPSFLRRSNSARYATSHSANPSLSPIAVRKPPQFVGKGLSALVQGLRDMEEERLEDDLDVLREIEAEQAALNVEVADSQAPAEIIGRHWKKKGQKRTTRRVRMKPVISKPASKPQSASDDENRHQAAGEEPAEPAAVPETQQPRALDAVFSEKQNEEFDDEDDQVSLHTISEPDLDSDPEYGEDIKPVTKSKSFSEKMKEAIGVAQPQPTEDPAKPSKPVIEAEETKKVRARKVNPEAHANYRSLKIRNKNSKGRGAGRFRRR

sld2

DNA replication regulator sld2

527 amino acids

Has a role in the initiation of DNA replication. Required at S-phase checkpoint (By similarity).

Belongs to the SLD2 family.

57.971 kDa

MASLDVSDIAAQSAQLRAELKEWERAFAAANEGRKAERSDIKQAPEIAAKYKEYSRLKSLEKSVRYEKKHNPNSVNLEERPKKRKHASPPGSHEARLESTPRKAAKGPFTTPSKPRGHPSEFDPYDSPSALRRLFSPSTHQQSSSPLKTAIGPTPQRDGKALGLFDLLSESGGSTATPTAARLASVRGAAAQTPSKRKTLDTIAEEEEEEDGPRGDRTPASASKSYMLSALFATPTTWRYATMMDNRNDAIRREPSPQPSANDAGQGAPESETPAFLRRSNSARYAASNPNGEGLSPINVRKRPRFVGKGLSALVQGLRDMEEEHLDNELDVLREIEAEQAGMNTEATDSQAVEQDTVPTFKKKGQKRTTRRVRMKPVISKPKCESQLPASEDEDNTDNVDQSDDELAAVPETQQPGASGDETNGVPDAASLHSISEPELDSDSDYEEQSKPPARSKSFSERIRDAIGVVEPPPAEKQEKPQPKVKEKQTKPRERKVNPEAHANYRSLKLRNKNSKGRGAGRFGRRR

SLD2

DNA replication regulator SLD2

470 amino acids

Has a role in the initiation of DNA replication. Required at S-phase checkpoint (By similarity).

Belongs to the SLD2 family.

52.491 kDa

MSITETEQRCNELRNDLKLWEKNFAAQNDGRKAGRDDIKANEEISNKYKEYNKLRGKLTAQSAPQTPSKRTASRKATRDAERTPKAAPKYQTSTPLKRKRAEELASEPIPQSPEFLSPQGPSVIGPTPQRDGIVLGLFDMLPAGTPSKRRAVLGDVELNILQTPSRRSQEAASETSLESRARGERTPVSVGKRFMLNQFVTPKKRKMEEEGTPSSTTRGLATPAFLRRGNLLGPIDEADETTPRPAPWKRRGLGRSLSAMIQAMKKDEDDKLDEEADIMREMEMEEAGISMPPKKLRVPQILVEDSQAAMPLGPDRGLETEEDEDEEPELGPDGKPRRVWKKKGLKRQTRRVIMRPNFIKSKLESALQLHDDSEDDQDKVAETQATGHAADDVDSEDDISDYASDVSHTPKQRKVQKKKTEEVKDQPKEGGVKTAARKIKATAHANFRRLKIKSSTGAKGGAKGKFGRRR

SLD2

DNA replication regulator SLD2

459 amino acids

Has a role in the initiation of DNA replication. Required at S-phase checkpoint (By similarity).

Belongs to the SLD2 family.

53.188 kDa

MPHQESITQLKQAIKVWEHEFQRSNNRIPSRSDIKVDPKVYELYKTYKVLKAKTNNVRNIQDKRTLESANIGIDINMSESQSDAEDVEEFNNENSDSSNNKLKNQDTELGPTPQANGKVLSILDIRLTPPDSSPLKNKVGSRSTDTYSNQKDEAPEDTFKTPTKTRVNRINLSELTPTNNRGPRNKSLMQKLEQASSAKNTRIEMHTPERNKVSLLQNMETPQYLAKVNNKFNFDMDDDSNDKDNVVAEDLHTNSSMKIISSIRSNIIDPITPTKSPAPLKFQVSPSPLKPHRLFSFGNNRKLSDIFNDYKNIKEDPDLINSIENEEEAAELDDDDDTIEKDTATNGPKRKRITQKRTTRRWKIKPNTEETKEDKLKNANIHDEVKKLDDEARKNLVDYMEVNNMHEEDETTSEEEYVHQDPNHKDMKGKVKPVRMNYQRLKINDPRIKKFKKRMQNRR

SLD2

DNA replication regulator SLD2

453 amino acids

Has a role in the initiation of DNA replication. Required at S-phase checkpoint. Also required for the proper activation of RAD53 in response to DNA damage and replication blocks.

Belongs to the SLD2 family.

52.272 kDa

MYSFELDKLKIELKTWEHDFIDKNKREPTRDDIKSLRTVRQMYKQYSTLKKKQSLQRQKVDTQESVELPAHKKDHDEVVEIGPTPQVYGKAISIFDMNLSPIKPIYMTFTNNIDVNNDNSKTISNESSPRKTILLKSSPADRTLVAEPISSVKRQLNFQMLNASSTRTPTSSPCKNRNGKLVEIKKCSPTINPPLESGKPSGYYGPNSPLKLDEENIHLNISLNSSTKRRLQIAYPSLQKTPSKDQADISTSFSPSPLIRRPLTKSLIELAREHTEIVKEFGVLQEEDIEEEEEGEEGENGYDEKNHEDDFGLEDELIRPKVVKDIFQEDDDNDDSQAREDTFIRKRPKRRKVIRRLRDNDPETETAGFERDVHKELVKLKRRKVAEFLGSTSQISDTEFEHDPEASSGVVSSEQKPTAKRKGRKKYNLVSNNFRRLKLPKKNRFSNGRWGRR

SLD2

DNA replication regulator SLD2

450 amino acids

Has a role in the initiation of DNA replication. Required at S-phase checkpoint (By similarity).

Belongs to the SLD2 family.

49.99 kDa

MDEDTRAEYESTSQQLRIDLKTWETDWAKSHEGKKPGRGDIKANEDIAAKYKQYNKVRDILSGKISPPSKHAPKSTKRKSDGLSAQTPIKQNKHIETPAKNRTQNHDEDLMNTPAISRKLFSPTSVTSVGPTPQRDGQVLGLFDLLVEKELGTPSKKDSATKTGSARKVDATPSKRSAATDDDEDERLGRTPMSSSKRQRLDHFLTPLKNKDGNKDAATPSSVSKLQFDTPAFLKRNTLPVLEENGDFDAPAPLRLPRKPFARGLSEIVASLRKVEEESLDDDLDALRDIEDGGMGEPKPKTLFPSKPKDDILVDDNEARQLPLGGFDDEGVYDSPVEGDNPTRVYKKKGQKRTTRMAKMRPVRVNRPENMAANPQSDVENDEIQAGGEDAGSDFDDIVEKKPAQKKEGTVKKAARKVNELAHANFQRLKLRNHGAKGGPGINSRFRRRK

SLD2

Delta(8)-fatty-acid desaturase 2

449 amino acids

Plays a major role as delta(8)-fatty-acid desaturase which introduces a double bond at the 8-position in the long-chain base (LCB) of ceramides with or without a hydroxy group at the 4-position. The enzyme produces both the 8E and 8Z isomers (in a 4:1 ratio). This structural modification contributes to the quantitative partitioning of ceramides between the two major sphingolipid classes, glucosylceramides and glycosylinositolphosphoryl ceramides. Sphingolipids are important membrane components involved in environmental stress responses, such as resistance to chilling, and act as cell signaling molecules.

Belongs to the fatty acid desaturase type 1 family.

51.498 kDa

MADQTKKRYVTSEDLKKHNKPGDLWISIQGKVYDVSDWVKSHPGGEAAILNLAGQDVTDAFIAYHPGTAWHHLEKLHNGYHVRDHHVSDVSRDYRRLAAEFSKRGLFDKKGHVTLYTLTCVGVMLAAVLYGVLACTSIWAHLISAVLLGLLWIQSAYVGHDSGHYTVTSTKPCNKLIQLLSGNCLTGISIAWWKWTHNAHHIACNSLDHDPDLQHIPIFAVSTKFFNSMTSRFYGRKLTFDPLARFLISYQHWTFYPVMCVGRINLFIQTFLLLFSKRHVPDRALNIAGILVFWTWFPLLVSFLPNWQERFIFVFVSFAVTAIQHVQFCLNHFAADVYTGPPNGNDWFEKQTAGTLDISCRSFMDWFFGGLQFQLEHHLFPRLPRCHLRTVSPVVKELCKKHNLPYRSLSWWEANVWTIRTLKNAAIQARDATNPVLKNLLWEAVNTHG

SLD2

DNA replication regulator SLD2

390 amino acids

Has a role in the initiation of DNA replication. Required at S-phase checkpoint (By similarity).

Belongs to the SLD2 family.

43.731 kDa

MDIQTLRSEIKAWERAYADKHGRKPTPKEVKADPIAKKYHLYNKFKKAESAGTGPSTPKRASKLHSSLNYKPVSFSVKTPEKQISKNRRRSVSKQQHADIVTPSHRSLTFSKAPALSRTPQKQLQDTPKAATPKPSPSVPLGPTPSIHGRVVSLLEGLDGTPVKEFATPGNVSTPVKVVSITSETPTNKPALDVNDEFTTPAYLNRISVDVSPFEKRLSFAERIRQSVVESPIKQMSPEKELSPANQTEEYDDDEDAWRELEGLPPKPKEPKIVDVTFDGEEPDELDEIMGTVEVHNPYDEPVQDDLDWVHETALEGETALSAPIYKEGGIKKRKHQTQKRTTKKAIVRVESEQHKKAKVDNDNFSTTNRLNTGFKVNMGQKQWASRFKK

SLD2

DNA replication regulator SLD2

379 amino acids

Has a role in the initiation of DNA replication. Required at S-phase checkpoint (By similarity).

Belongs to the SLD2 family.

42.509 kDa

MSRTSAGELDVLKVQLKTWERQFLEENGRSPIKEDIKAHPEIRRKYKEYTSLKKLLSKGNAAVTGQKHGSPSRATHPTPQKHIDAEIELGPTPQIYGKVVSLFEMHISPLKKVPVRQLDADSSETCISPDLHSQDVAQSELLTDISCQAKRQLDFSVTPHASPVKAVQPLLLNAPDLRFEAIPHARTKYGPNSPVKFDGDVTLTLSQTPLQAKLAQASEGYSPSPLIKRPAKPLSQLAKEYEDIVEELKEVDHAAAVRNLGGLLQQEEENTQEAEAAEPSATRSDRKRRKNKVRPALVTLEEEIPQGNLHEQLVKLRQKALDKFNGNDPNDSSDEEKKTSATSAKPAKARKRKYNTVSDNFRRLKLPTKNTRNGRWRRR

SLD2

DNA replication regulator SLD2

379 amino acids

Has a role in the initiation of DNA replication. Required at S-phase checkpoint (By similarity).

Belongs to the SLD2 family.

43.088 kDa

MNGIKETDTVNAPLLLVISSASMDALKIEIKLWERAFEKEHGRLPEKDDIKKDKEVKRKYKQYAQLKKDATVKPSVEVNVEQTPVKSHVNNTKAEFGPTPQMNGKLVSIFEMQVSAMKTHQSDQEDIVGSPVRSNDLVRRQLNFSITPNSSPMKQVPNLSANIVVSRPKYGPNSPMRIGDIGLQLSETPKTLGRTLDLKSSPFSPSPLIKRPVKTLSQLAKEHAIIKDEFESNPEDFSEFTAIRTLMEKLMQEEHMDIIEEGDEGTVGNETESNYVRKVKTIKKRTKAKMRPAALNEKSTNIPDKNVHEQLAKLKEREYNKMLGKEVEESESDSEQQSNPPVKKKQRKSKYNLVSNNFKRLNLPTKAGRNRASKWRGRR

SLD2

DNA replication regulator SLD2

354 amino acids

Has a role in the initiation of DNA replication. Required at S-phase checkpoint (By similarity).

Belongs to the SLD2 family.

40.672 kDa

MDIVEIKSKIKEWEYAFRKQHNKLPSKADIKDDVEIHKLYSLYKSIKSGQQQKPSKQETVNEPASVQSSPVKRNDYSPRGELGPTPQANGRVLSIFDLKMTPPDSSPLKHKSDKASPSAFAMPPPQSPVKNIIETPTKSKNKSFVTPIKGRKIVFETPSYLNKHRQNPQTPDSHNNNNNNNNNTVINFSVSPSPFKTQRSIGKRLTEVYNTSLKEAEDLKSFNLEEEFQSHEEQESEETETTTNNDRKIAPRSKRTQKRSTRRVKMAPRPVNSKPSLENVNLQDHITKLEEGERKQLVAYMDSDEDDENRDGEVGIASVFESPTKKTRMPVSNNFKRLKINDPRSRRFKQRMRR

SLD2

DNA replication regulator SLD2

350 amino acids

Has a role in the initiation of DNA replication. Required at S-phase checkpoint (By similarity).

Belongs to the SLD2 family.

40.992 kDa

MDMDVQQVKLKIKRWEHAFIAEHNRPPDKDDIRPLTEMKQLYKLYSVLKSKERKAEPIQKQQTPRKDSNMVLGPTPQIYGKAVSIFEMKVSPLKVEETPTTEVEEDIESEIESSVNRRNSDEASANEEKLGIHSVKKRLFESPKKTENTTHLAVPQVTRYGPNSPLKLAQTVSIRQHLLTPKKKKAEPKSLYTPSPLLKRNSSKTLYELAHEHLQYVEEIKELDQQFKSEIVPIRHGNGQDIGDESDEVPEKKKRRTGVLRRLQFDEDENDRTIKKDLHKELLKLKSRKVKEFLGKEDNEPSEEEEEEQQKSEPLPVKKKKPKKYNLVSNNFRRLKLPKKNRNPRFGRRR