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SLC6A12

Gene
SLC6A12
Protein
Sodium- and chloride-dependent betaine transporter
Organism
Canis lupus familiaris
Length
614 amino acids
Function
Transports betaine and GABA. May have a role in regulation of GABAergic transmission in the brain through the reuptake of GABA into presynaptic terminals, as well as in osmotic regulation.
Similarity
Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. SLC6A12 subfamily.
Mass
69.292 kDa
Sequence
MDRKVAVPEDGPPVVSWLPEEGEKLDQEGEDQVKDRGQWTNKMEFVLSVAGEIIGLGNVWRFPYLCYKNGGGAFFIPYFIFFFTCGIPVFFLEVALGQYTSQGSVTAWRKICPLLQGIGLASVVIESYLNIYYIIILAWALFYLFSSFTSELPWTTCTNTWNTEHCMDFLNHSGARTATSSENFTSPVMEFWERRVLGITSGIHDLGALRWELALCLLLAWLICYFCIWKGVKTTGKVVYFTATFPYLMLVILLIRGITLPGAYQGVIYYLKPDLLRLKDPQVWMDAGTQIFFSFAICQGCLTALGSYNKYHNNCYRDSIALCFLNSATSFAAGFVVFSILGFMAQEQGLPISEVAESGPGLAFIAFPKAVTMMPLSQLWSCLFFIMLIFLGLDSQFVCVECLVTASMDMFPSQLRKSGRRELLILAIAVFCYLAGLFLVTEGGMYIFQLFDYYASSGICLLFLAMFEVICISWVYGADRFYDNIEDMIGYRPWPLVKISWLFLTPGLCLATFLFSLSQYTPLKYNNIYVYPPWGYSIGWFLALSSMICVPLFVIITLLKTRGSFKKRLRQLTTPDPSLPQPKQHLYLDGGTSQDCGPSPTKEGLIVGEKETHL
Protein
Sodium- and chloride-dependent betaine transporter: SLC6A12

Gene
SLC6A12
Protein
Sodium- and chloride-dependent betaine transporter
Organism
Homo sapiens
Length
614 amino acids
Function
Transports betaine and GABA. May have a role in regulation of GABAergic transmission in the brain through the reuptake of GABA into presynaptic terminals, as well as in osmotic regulation.
Similarity
Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. SLC6A12 subfamily.
Mass
69.368 kDa
Sequence
MDGKVAVQECGPPAVSWVPEEGEKLDQEDEDQVKDRGQWTNKMEFVLSVAGEIIGLGNVWRFPYLCYKNGGGAFFIPYFIFFFVCGIPVFFLEVALGQYTSQGSVTAWRKICPLFQGIGLASVVIESYLNVYYIIILAWALFYLFSSFTSELPWTTCNNFWNTEHCTDFLNHSGAGTVTPFENFTSPVMEFWERRVLGITSGIHDLGSLRWELALCLLLAWVICYFCIWKGVKSTGKVVYFTATFPYLMLVILLIRGVTLPGAYQGIIYYLKPDLFRLKDPQVWMDAGTQIFFSFAICQGCLTALGSYNKYHNNCYKDCIALCFLNSATSFVAGFVVFSILGFMSQEQGVPISEVAESGPGLAFIAFPKAVTMMPLSQLWSCLFFIMLIFLGLDSQFVCVECLVTASIDMFPRQLRKSGRRELLILTIAVMCYLIGLFLVTEGGMYIFQLFDYYASSGICLLFLSLFEVVCISWVYGADRFYDNIEDMIGYRPWPLVKISWLFLTPGLCLATFLFSLSKYTPLKYNNVYVYPPWGYSIGWFLALSSMVCVPLFVVITLLKTRGPFRKRLRQLITPDSSLPQPKQHPCLDGSAGRNFGPSPTREGLIAGEKETHL
Protein
Sodium- and chloride-dependent betaine transporter: SLC6A12

Gene
Slc6a12
Protein
Sodium- and chloride-dependent betaine transporter
Organism
Mus musculus
Length
614 amino acids
Function
Transports betaine and GABA. May have a role in regulation of GABAergic transmission in the brain through the reuptake of GABA into presynaptic terminals, as well as in osmotic regulation (By similarity).
Similarity
Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. SLC6A12 subfamily.
Mass
69.614 kDa
Sequence
MDRKVAVHEDGYPVVSWVPEEGEMMDQKGKDQVKDRGQWTNKMEFVLSVAGEIIGLGNVWRFPYLCYKNGGGAFFIPYFIFFFSCGIPVFFLEVALGQYSSQGSVTAWRKICPLLQGIGMASVVIESYLNIYYIIILAWALFYLFSSFTWELPWTTCTNSWNTEHCVDFLNHSSARGVSSSENFTSPVMEFWERRVLGITSGIHDLGSLRWELALCLLLAWIICYFCIWKGVKSTGKVVYFTATFPYLMLIILLIRGVTLPGAYQGIVFYLKPDLLRLKDPQVWMDAGTQIFFSFAICQGCLTALGSYNKYHNNCYRDSIALCFLNSATSFVAGFVVFSILGFMSQEQGIPISEVAESGPGLAFIAFPKAVTMMPLSQLWSCLFFIMLLFLGLDSQFVCMECLVTASMDMFPQQLRKSGRRDVLILAISVLCYLMGLLLVTEGGMYIFQLFDYYASSGICLLFLSLFEVICIGWVYGADRFYDNVEDMIGYRPWPLVKISWLFLTPGLCLATFFFSLSKYTPLKYNNVYMYPSWGYSIGWLLAFSSMACVPLFIIITFLKTQGSFKKRLRRLITPDPSLPQPGRRPPQDGSSAQNCSSSPAKQELIAWEKETHL
Protein
Sodium- and chloride-dependent betaine transporter: Slc6a12

Gene
SLC6A12
Protein
Sodium- and chloride-dependent betaine transporter
Organism
Oryctolagus cuniculus
Length
614 amino acids
Function
Transports betaine and GABA. May have a role in regulation of GABAergic transmission in the brain through the reuptake of GABA into presynaptic terminals, as well as in osmotic regulation (By similarity).
Similarity
Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. SLC6A12 subfamily.
Mass
69.111 kDa
Sequence
MDTKLAVHEDAPPLVSWVPEEGEKLEQEGEDQAKDRGQWTNKMEFVLSVAGEIIGLSNVWRFPYLCYKNGGGAFFVPYFIFFFSCGIPVFFLEVALGQYTSQGSVTAWKKICPLFQGIGLASVVIESYLNVYYIIILAWALFYLFSSFTSELPWTTCTNSWNTEYCQHALNHSGAGIGSSTENFTSPVMEFWERRVLGITAGIHDLGALRWELALCLLLAWIVCYFCIWKGVKYTGKVVYFTATFPYLMLVILLIRGVTLPGAYQGIVYYLKPDLLRLKDPQVWMDAGTQIFFSFAICQGCLTALGSYNKYHNNCYRDSIALCFLNSATSFVAGFVVFSVLGFMSQEQGVPISEVAESGPGLAFIAFPKAVTMMPLSQLWSCLFFIMLIFLGLDSQFVCMECLVTASVDMFPRQLRKSGRRELLILAIAVLCYLIGLLLVTEGGMYIFQLFDYYACSGICLLFLSVFEVVSISWVYGADRFYDNIQDMIGYRPWPLVKISWLFLTPGLCLATFLFSLSKYSPLRYNNVYVYPAWGYCVGWFLAFSSMACVPLCIVIALLKAQGSFTKRLRQLITPDPSLPQPTQQLRLDSGPGQDRRPSPAKEGLVTVEKETHL
Protein
Sodium- and chloride-dependent betaine transporter: SLC6A12

Gene
Slc6a12
Protein
Sodium- and chloride-dependent betaine transporter
Organism
Rattus norvegicus
Length
614 amino acids
Function
Transports betaine and GABA. May have a role in regulation of GABAergic transmission in the brain through the reuptake of GABA into presynaptic terminals, as well as in osmotic regulation (By similarity).
Similarity
Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. SLC6A12 subfamily.
Mass
69.749 kDa
Sequence
MDRKVTVHEDGCPVVSWVPEEGEMMDQKDKDQVKDRGQWTNKMEFVLSVAGEIIGLGNVWRFPYLCYKNGGGAFFIPYFIFFFSCGIPVFFLEVALGQYSSQGSVTAWRKICPLLQGIGMASVVIESYLNIYYIIILAWALFYLFSSFTWELPWTTCTNSWNTEHCVDFLNYSSTRAASYSENFTSPVMEFWERRVLGITSGIHDLGSLRWELALCLLLAWIICYFCIWKGVKSTGKVVYFTATFPYLMLIILLIRGVTLPGAYQGIVFYLKPDLLRLKDPQVWMDAGTQIFFSFAICQGCLTALGSYNKYHNNCYRDSIALCFLNSATSFVAGFVVFSILGFMAQEQGVPISEVAESGPGLAFIAFPKAVTMMPLSQLWSCLFFLMLLFLGLDSQFVCMECLVTASMDMFPQQLRKRGRRELLILAVAIVCYLMGLLLVTEGGMYIFQLFDYYASSGICLLFLSLFEVICIGWVYGADRFYDNVEDMIGYRPWPLVKISWLFLTPGLCLATFFFSLSKYTPLKYNNVYIYPSWGYSIGWLLAFSSMACVPLFIIITLLKTQGSFKKRLQRLITPDPSLPQPGRRSPQDGSSAQNCSTSPVKQELIAWEKETHL
Protein
Sodium- and chloride-dependent betaine transporter: Slc6a12