slc5a12

Sodium-coupled monocarboxylate transporter 2

623 amino acids

Acts as an electroneutral and low-affinity sodium (Na(+))-dependent sodium-coupled solute transporter. Catalyzes the transport across the plasma membrane of many monocarboxylates such as lactate, pyruvate, nicotinate, propionate, butyrate and beta-D-hydroxybutyrate.

Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.

67.32 kDa

METVGRFQAGDYVVFACLFVVSSGIGVFFAIKERNKAPSKEFLVGGRQMSCGPVALSLTASFMSAVTVIGAPADVYRFGASYVIFGVAYTFVVFFTAELFLPVFYRSGITSTYEYLELRFCKLVRVAATLIYIIQTILYTGVVVYAPALALNQVTGFDLWGSIFATGIVCTFYCTLGGLKAVVWTDAFQMVVMVVGFLTVLIQGSSRAGGIENVWSTSRTGGRLQVFDFDVSPLRRHTFWTLSVGGTFTWLGIYGVNQSTIQRCISCKTEGHARWALYLNLLGLWIILFCAVVSGLIMYSYYSHCDPWSSGLISAPDQLMPYFVMEILGAFPGLPGLFVACAFSGTLSTVAASINALATVMYEDFVSQCFPDLSNRAASWISKALCVAFGVACTTMAVAASYMGGIVQAALSIHGMCGGPVLGLFSLGILFPFTNLKGAVGGLIVGISLSFWVGVGAFIYPAPSNNTHALELNTAGCNITAAAFEPTSATVTQLTSDRNWLADSWYSMSYLYYSAVGFIGTVAAGLLITLLTGPMDPKLLKPGMTRSVKEVMCFCTEKFTEADLGEGKEDVGDFGKAWEKHPDQGCTLRMDEKFRCSCDNQQENGNTNAGFDHNETSIVQKKL

Slc5a12

Sodium-coupled monocarboxylate transporter 2

619 amino acids

Acts as an electroneutral and low-affinity sodium (Na(+))-dependent sodium-coupled solute transporter. Catalyzes the transport across the plasma membrane of many monocarboxylates such as lactate, pyruvate, nicotinate, propionate, butyrate and beta-D-hydroxybutyrate. May be responsible for the first step of reabsorption of monocarboxylates from the lumen of the proximal tubule of the kidney and the small intestine. May play also a role in monocarboxylates transport in the retina. Mediates electroneutral uptake of lactate, with a stoichiometry of 2 Na(+) for each lactate.

Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.

67.951 kDa

MRVKNFEAWDYVVFAGLFVISSGIGVFFAIKERKKTTSREFLVGGRQMSFGPVALSLTASFMSAVTVLGTPAEVYRFGASFFLFLISYVFVVFFTSELFLPVFYRSGITSTYEYLQLRFNKPVRYAATIIYIVQTILYTGVVVYAPALALNQVTGFNLWASVFATGIVCTFYCSLGGLKAVVWTDAFQMVVMIVGFLTVLIQGSNHVGGFNNVLEKAGNGSRLHIVDFDVDPLRRHTFWTITIGGTFTWLGVYGVNQSTIQRCISCKTEKHAKLALYFNLLGLWIIVACAVFSGLIMYSHFKDCDPWTSGVISAPDQLMPYFVMEIFATMPGLPGLFVACAFSGTLSTVAASINALATVTFEDFVKSCFPHLSDKLSTWISKGLCILFGIMCTSMAVVASLMGSVVQAALSIHGMCGGPMLGLFTLGLVFPFVNWKGALGGLLTGITLSFWVAIGSFIYPAPESKTLPLPLSTEHCVELNITTTVAPQISSRPVLADTWYSLSYLYFSAVGCLGCIAAGIIISFLTGKQRGKDIDPLLIRPVCNLFCFWSKKYKTLCWCGVQHDRETEQDYLDSGSAWKQGVESGLQNGLKQDTLAQIPGYNPKEKSYSNSVPEKTTYF

SLC5A12

Sodium-coupled monocarboxylate transporter 2

618 amino acids

Acts as an electroneutral and low-affinity sodium (Na(+))-dependent sodium-coupled solute transporter. Catalyzes the transport across the plasma membrane of many monocarboxylates such as lactate, pyruvate, nicotinate, propionate, butyrate and beta-D-hydroxybutyrate. May be responsible for the first step of reabsorption of monocarboxylates from the lumen of the proximal tubule of the kidney and the small intestine. May play also a role in monocarboxylates transport in the retina (By similarity). Mediates electroneutral uptake of lactate, with a stoichiometry of 2 Na(+) for each lactate (By similarity).

Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.

67.647 kDa

MEVKNFAVWDYVVFAALFFISSGIGVFFAIKERKKATSREFLVGGRQMSFGPVGLSLTASFMSAVTVLGTPSEVYRFGASFLVFFIAYLFVILLTSELFLPVFYRSGITSTYEYLQLRFNKPVRYAATVIYIVQTILYTGVVVYAPALALNQVTGFDLWGSVFATGIVCTFYCTLGGLKAVVWTDAFQMVVMIVGFLTVLIQGSTHAGGFHNVLEQSTNGSRLHIFDFDVDPLRRHTFWTITVGGTFTWLGIYGVNQSTIQRCISCKTEKHAKLALYFNLLGLWIILVCAVFSGLIMYSHFKDCDPWTSGIISAPDQLMPYFVMEIFATMPGLPGLFVACAFSGTLSTVASSINALATVTFEDFVKSCFPHLSDKLSTWISKGLCLLFGVMCTSMAVAASVMGGVVQASLSIHGMCGGPMLGLFSLGIVFPFVNWKGALGGLLTGITLSFWVAIGAFIYPAPASKTWPLPLSTDQCIKSNVTATGPPVLSSRPGIADTWYSISYLYYSAVGCLGCIVAGVIISLITGRQRGEDIQPLLIRPVCNLFCFWSKKYKTLCWCGVQHDSGTEQENLENGSARKQGAESVLQNGLRRESLVHVPGYDPKDKSYNNMAFETTHF

SLC5A12

Sodium-coupled monocarboxylate transporter 2

617 amino acids

Acts as an electroneutral and low-affinity sodium (Na(+))-dependent sodium-coupled solute transporter. Catalyzes the transport across the plasma membrane of many monocarboxylates such as lactate, pyruvate, nicotinate, propionate, butyrate and beta-D-hydroxybutyrate. May be responsible for the first step of reabsorption of monocarboxylates from the lumen of the proximal tubule of the kidney and the small intestine. May play also a role in monocarboxylates transport in the retina. Mediates electroneutral uptake of lactate, with a stoichiometry of 2 Na(+) for each lactate (By similarity).

Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.

67.41 kDa

MEVKNFAVWDYVVFAALFIISSGIGVFYAIKERKKATSREFLVGGRQMSFGPVALSLTASFMSAVTVLGTPADVYRFGASFVLFFITYGLVIILTSELFLPVFYRSGITSTYEYLQLRFNKPVRYAATVIYIVQTILYTGVVVYAPALALNQVTGFDLWGSVFATGIVCTFYCTLGGLKAVVWTDAFQMVVMIVGFLTVLIQGSTYAGGLHNVLEQAENGSRLNIFDFDIDPLRRHTFWTISVGGTFTWLGIYGVNQSTIQRCISCKTEKHAKLALYFNLLGLWIILLCAVFSGLTMYAHFKDCDPWTSGIISAPDQLMPYFVMELFSTMPGLPGLFVACAFSGTLSTVAASINALATVTFEDFVKSCFPRLSDKLSTWISKGLCLLFGVICTSTAVAASLMGGVIQAALSIHGMCGGPMLGLFSLGILFPFVNWKGALAGLLTGILLSFWVAIGAFIYPAPASKTWPLPLSTDQCGLSNVTESVPPVLSSRPAIAETWYALSYLHYSTVGCLGCIAAGVIISFLTGLQKGKDIPPLLIRPVCNLFCFWSKKYKTLCWCGVQHDSGTEQENLENDSTWKQGAESVLQNGLKQESLVPGYDPKDKSYDNMALEKITHF