Slc4a1

Band 3 anion transport protein

929 amino acids

Functions both as a transporter that mediates electroneutral anion exchange across the cell membrane and as a structural protein. Major integral membrane glycoprotein of the erythrocyte membrane; required for normal flexibility and stability of the erythrocyte membrane and for normal erythrocyte shape via the interactions of its cytoplasmic domain with cytoskeletal proteins, glycolytic enzymes, and hemoglobin. Functions as a transporter that mediates the 1:1 exchange of inorganic anions across the erythrocyte membrane. Mediates chloride-bicarbonate exchange in the kidney, and is required for normal acidification of the urine.

Belongs to the anion exchanger (TC 2.A.31) family.

103.136 kDa

MGDMRDHEEVLEIPDRDSEEELENIIGQIAYRDLTIPVTEMQDPEALPTEQTATDYVPSSTSTPHPSSGQVYVELQELMMDQRNQELQWVEAAHWIGLEENLREDGVWGRPHLSYLTFWSLLELQKVFSKGTFLLGLAETSLAGVANHLLDCFIYEDQIRPQDREELLRALLLKRSHAEDLGNLEGVKPAVLTRSGGASEPLLPHQPSLETQLYCGQAEGGSEGPSTSGTLKIPPDSETTLVLVGRANFLEKPVLGFVRLKEAVPLEDLVLPEPVGFLLVLLGPEAPHVDYTQLGRAAATLMTERVFRITASMAHNREELLRSLESFLDCSLVLPPTDAPSEKALLNLVPVQKELLRRRYLPSPAKPDPNLYNTLDLNGGKGGPGDEDDPLRRTGRIFGGLIRDIRRRYPYYLSDITDALSPQVLAAVIFIYFAALSPAVTFGGLLGEKTRNLMGVSELLISTAVQGILFALLGAQPLLVLGFSGPLLVFEEAFFSFCESNNLEYIVGRAWIGFWLILLVMLVVAFEGSFLVQYISRYTQEIFSFLISLIFIYETFSKLIKIFQDYPLQQTYAPVVMKPKPQGPVPNTALFSLVLMAGTFLLAMTLRKFKNSTYFPGKLRRVIGDFGVPISILIMVLVDSFIKGTYTQKLSVPDGLKVSNSSARGWVIHPLGLYRLFPTWMMFASVLPALLVFILIFLESQITTLIVSKPERKMIKGSGFHLDLLLVVGMGGVAALFGMPWLSATTVRSVTHANALTVMGKASGPGAAAQIQEVKEQRISGLLVSVLVGLSILMEPILSRIPLAVLFGIFLYMGVTSLSGIQLFDRILLLFKPPKYHPDVPFVKRVKTWRMHLFTGIQIICLAVLWVVKSTPASLALPFVLILTVPLRRLILPLIFRELELQCLDGDDAKVTFDEENGLDEYDEVPMPV

Slc4a1

Band 3 anion transport protein

927 amino acids

Functions both as a transporter that mediates electroneutral anion exchange across the cell membrane and as a structural protein. Major integral membrane glycoprotein of the erythrocyte membrane; required for normal flexibility and stability of the erythrocyte membrane and for normal erythrocyte shape via the interactions of its cytoplasmic domain with cytoskeletal proteins, glycolytic enzymes, and hemoglobin. Functions as a transporter that mediates the 1:1 exchange of inorganic anions across the erythrocyte membrane. Mediates chloride-bicarbonate exchange in the kidney, and is required for normal acidification of the urine.

Belongs to the anion exchanger (TC 2.A.31) family.

103.173 kDa

MGDMQDHEKVLEIPDRDSEEELEHVIEQIAYRDLDIPVTEMQESEALPTEQTATDYIPTSTSTSHPSSSQVYVELQELMMDQRNQELQWVEAAHWIGLEENLREDGVWGRPHLSYLTFWSLLELQKVFSKGTFLLDLAETSLAGVANKLLDSFIYEDQIRPQDRDELLRALLLKRSHAEDLKDLEGVKPAVLTRSGAPSEPLLPHQPSLETKLYCAQAEGGSEEPSPSGILKIPPNSETTLVLVGRASFLVKPVLGFVRLKEAVPLEDLVLPEPVSFLLVLLGPEAPHIDYTQLGRAAATLMTERVFRVTASLAQSRGELLSSLDSFLDCSLVLPPTEAPSEKALLNLVPVQKELLRKRYLPRPAKPDPNLYEALDGGKEGPGDEDDPLRRTGRIFGGLIRDIRRRYPYYLSDITDALSPQVLAAVIFIYFAALSPAVTFGGLLGEKTRNLMGVSELLISTAVQGILFALLGAQPLLVLGFSGPLLVFEEAFYSFCESNNLEYIVGRAWIGFWLILLVVLVVAFEGSFLVQYISRYTQEIFSFLISLIFIYETFSKLIKIFQDYPLQESYAPVVMKPKPQGPVPNTALLSLVLMVGTFLLAMMLRKFKNSTYFPGKLRRVIGDFGVPISILIMVLVDTFIKNTYTQKLSVPDGLKVSNSSARGWVIHPLGLYNHFPKWMMFASVLPALLVFILIFLESQITTLIVSKPERKMIKGSGFHLDLLLVVGMGGVAALFGMPWLSATTVRSVTHANALTVMGKASGPGAAAQIQEVKEQRISGLLVSVLVGLSILMEPILSRIPLAVLFGIFLYMGITSLSGIQLFDRILLLFKPPKYHPDVPFVKRVKTWRMHLFTGIQIICLAVLWVVKSTPASLALPFVLILTVPLRRLLLPLIFRELELQCLDGDDAKVTFDEAEGLDEYDEVPMPV

SLC4A1

Band 3 anion transport protein

922 amino acids

Functions both as a transporter that mediates electroneutral anion exchange across the cell membrane and as a structural protein. Major integral membrane glycoprotein of the erythrocyte membrane; required for normal flexibility and stability of the erythrocyte membrane and for normal erythrocyte shape via the interactions of its cytoplasmic domain with cytoskeletal proteins, glycolytic enzymes, and hemoglobin. Functions as a transporter that mediates the 1:1 exchange of inorganic anions across the erythrocyte membrane. Mediates chloride-bicarbonate exchange in the kidney, and is required for normal acidification of the urine.

Belongs to the anion exchanger (TC 2.A.31) family.

102.223 kDa

MEGPGQDTEDALRRSLDPEGYEDTKGSRTSLGTMSNPLVSDVDLEAAGSRQPTAHRDTYEGYVELHELVLDSRKDPCWMEAGRWLHLEESMEPGGAWGSHLPLLTYHSLLELHRAFAKGVVLLDVAANSLAAVAHVLLDQLIYEGQLKPQHRDDVLRALLLRHKHPSEAESVWTLPAAQLQCSDGEQKDADERALLRDQRAVEMRELHGAGQSPSRAQLGPQLHQQLPEDTEATLVLVACAAFLEQPLLALVRLGAPCPDAVLAVPLPVRFVLTVLGPDSPRLSYHEIRRAAATVMADRVFRRDAYLCGGRAELLGGLQGFLEASIVLPPQEVPSEQHLHALIPLQRHAVRRRYQHPDTVRSPGGPTAPKDTGDKGQAPQDDDPLLRTRRPFGGLVRDIRRRYPKYLSDIRDALNPQCLAAVIFIYFAALSPAITFGGLLGEKTRGMMGVSELLLSTSVQCLLFSLLSAQPLLVVGFSGPLLVFEEAFFRFCEDHGLEYIVGRVWIGFWLILLVLLVVACEGTVLVRYLSRYTQEIFSFLISLIFIYETFAKLVTIFEAHPLQQSYDTDVSTEPSVPKPNTALLSLVLMAGTFFLALFLRQFKNSVFLPGKVRRLIGDFGVPISIFVMALADFFIKDTYTQKLKVPRGLEVTNGTARGWFIHPMGSATPFPIWMMFASPVPALLVFILIFLETQITTLIVSKPERKLVKGSGFHLDLLLIVAMGGLAALFGMPWLSATTVRTITHANALTVVGKSAVPGERAHIVEVKEQRLSGLLVAVLIGVSILMEPILKYIPLAVLFGIFLYMGVTSLFGIQLFDRILLLLMPPKYHPKEPYVTRVKTWRITSSPLTQILVVALLWGVKVSPASLRCPFVLVLTVPLRRLLLPRIFSEIELKCLDTDDAVVTFEEAEGQDVYNEVQMPS

slc4a1

Band 3 anion exchange protein

918 amino acids

Functions both as a transporter that mediates electroneutral anion exchange across the cell membrane and as a structural protein. Major integral membrane glycoprotein of the erythrocyte membrane; required for normal flexibility and stability of the erythrocyte membrane and for normal erythrocyte shape via the interactions of its cytoplasmic domain with cytoskeletal proteins, glycolytic enzymes, and hemoglobin. Functions as a transporter that mediates the 1:1 exchange of inorganic anions across the erythrocyte membrane. Mediates chloride-bicarbonate exchange in the kidney, and is required for normal acidification of the urine.

Belongs to the anion exchanger (TC 2.A.31) family.

101.894 kDa

MENDLSFGEDVMSYEEESDSAFPSPIRPTPPGHSGNYDLEQSRQEEDSNQAIQSIVVHTDPEAYLNLNTNANTRGDAQAYVELNELMGNSWQETGRWVGYEENFNPGTGKWGPSHVSYLTFKSLIQLRKIMSTGAIILDLQASSLSAVAEKVVDELRTKGEIRAADRDGLLRALLQRRSQSEGAVAQPLGGDIEMQTFSVTKQRDTTDSVEASIVLSGVMDSLEKPAVAFVRLGDSVVIEGALEAPVPVRFVFVLVGPSQGGVDYHESGRAMAALMADWVFSLEAYLAPTNKELTNAIADFMDCGIVIPPTEIQDEGMLQPIIDFQKKMLKDRLRPSDTRIIFGGGAKADEADEEPREDPLARTGIPFGGMIKDMKRRYRHYISDFTDALDPQVLAAVIFIYFAALSPAITFGGLLADKTEHMMGVSELMISTCVQGIIFAFIAAQPTLVIGFSGPLLVFEEAFFAFCKSQEIEYIVGRIWVGLWLVIIVVVIVAVEGSFLVKFISRFTQEIFSILISLIFIYETFSKLGKIFKAHPLVLNYEHLNDSLDNPFHPVVKEHIEYHEDGNKTVHEVIHERAYPNTALLSMCLMFGCFFIAYFLRQFKNGHFLPGPIRRMIGDFGVPIAIFFMIAVDITIEDAYTQKLVVPKGLMVSNPNARGWFINPLGEKKPFPAWMMGACCVPALLVFILIFLESQITTLIVSKPERKMVKGSGFHLDLLILVTMGGIASLFGVPWLSAATVRSVTHANALTVMSKGPKPEIEKVLEQRISGMLVAAMVGVSILLEPILKMIPMTALFGIFLYMGITSLSGIQMWDRMLLLIVPRKYYPADAYAQRVTTMKMHLFTLIQMVCLGALWMVKMSAFSLALPFVLILTIPLRMAITGTLFTDKEMKCLDASDGKVKFEEEPGEDMYESPLP

SLC4A1

Band 3 anion transport protein

911 amino acids

Functions both as a transporter that mediates electroneutral anion exchange across the cell membrane and as a structural protein. Major integral membrane glycoprotein of the erythrocyte membrane; required for normal flexibility and stability of the erythrocyte membrane and for normal erythrocyte shape via the interactions of its cytoplasmic domain with cytoskeletal proteins, glycolytic enzymes, and hemoglobin. Functions as a transporter that mediates the 1:1 exchange of inorganic anions across the erythrocyte membrane. Mediates chloride-bicarbonate exchange in the kidney, and is required for normal acidification of the urine.

Belongs to the anion exchanger (TC 2.A.31) family.

101.792 kDa

MEELQDDYEDMMEENLEQEEYEDPDIPESQMEEPAAHDTEATATDYHTTSHPGTHKVYVELQELVMDEKNQELRWMEAARWVQLEENLGENGAWGRPHLSHLTFWSLLELRRVFTKGTVLLDLQETSLAGVANQLLDRFIFEDQIRPQDREELLRALLLKHSHAGELEALGGVKPAVLTRSGDPSQPLLPQHSSLETQLFCEQGDGGTEGHSPSGILEKIPPDSEATLVLVGRADFLEQPVLGFVRLQEAAELEAVELPVPIRFLFVLLGPEAPHIDYTQLGRAAATLMSERVFRIDAYMAQSRGELLHSLEGFLDCSLVLPPTDAPSEQALLSLVPVQRELLRRRYQSSPAKPDSSFYKGLDLNGGPDDPLQQTGQLFGGLVRDIRRRYPYYLSDITDAFSPQVLAAVIFIYFAALSPAITFGGLLGEKTRNQMGVSELLISTAVQGILFALLGAQPLLVVGFSGPLLVFEEAFFSFCETNGLEYIVGRVWIGFWLILLVVLVVAFEGSFLVRFISRYTQEIFSFLISLIFIYETFSKLIKIFQDHPLQKTYNYNVLMVPKPQGPLPNTALLSLVLMAGTFFFAMMLRKFKNSSYFPGKLRRVIGDFGVPISILIMVLVDFFIQDTYTQKLSVPDGFKVSNSSARGWVIHPLGLRSEFPIWMMFASALPALLVFILIFLESQITTLIVSKPERKMVKGSGFHLDLLLVVGMGGVAALFGMPWLSATTVRSVTHANALTVMGKASTPGAAAQIQEVKEQRISGLLVAVLVGLSILMEPILSRIPLAVLFGIFLYMGVTSLSGIQLFDRILLLFKPPKYHPDVPYVKRVKTWRMHLFTGIQIICLAVLWVVKSTPASLALPFVLILTVPLRRVLLPLIFRNVELQCLDADDAKATFDEEEGRDEYDEVAMPV