SLC44A4

Gene

slc44a4

Protein

Choline transporter-like protein 4

Organism

Danio rerio

Length

723 amino acids

Function

Choline transporter that seems to play a role in the choline-acetylcholine system and is required to the efferent innervation of hair cells in the olivocochlear bundle for the maintenance of physiological function of outer hair cells and the protection of hair cells from acoustic injury.

Similarity

Belongs to the CTL (choline transporter-like) family.

Mass

80.873 kDa

Sequence

MGKKKQEEEQNSSEYGAPAQYDPTFNGPIHKRSCTDIICCVLFMLVITGYMVVGILAWLYGDPRHVLYPRNSTGMFCGIGQNQNKPSVLYFDILKCATATNIMAAALQGLQCPTTQVCVSSCPSGFWALSPLAYLPNAKPADYFQQELCVPSLQLKDTTYTVMEIINKELCPYYYTPTTSVLDRCLPSLGGSAYNPSNIPANFSLPGLSINQTLSTIANATSDLTNSFNMKDVGLRIFEDFAKTWQWIVAGLVIAMVVSVLFLLLLRFTAPVLIWILIFGVLAVGAFGIWYCYNDYMSLASSNLTFSNVGFTTNVQVYLQVRDTWLAFLIILCIVEAVLILALIFLRTRILIAIALIQETSKALGHMMSTLLYPVVTFVLLLVCVSYWGITALYLATSGAPIYKVVALNTTQGDCSNIQANQTCDPQTFNSSRYSSCPSARCVFINYNTEGLFQRNLFNLQIYNVVAFLWCVNFVIALGHCTLAGAFASYYWAFSKPADIPTFPLTQSFMRALRYHVGSLAFGALILTLVQIVRIILEYLDHKFKAAQNPCARFLMCCLKCCFWCLEKFIKFINRNAYIMIAIYGKNFCVSAKNAFFLLMRNIVRVVVLDKVTDLLLFFGKLLVVGGIGVLAFFFFSGRIQLPGNTFQTAALNYYWMPIITVVFGAYLIAHGFFSVYNMGVDTLFLCFLEDLERNDGSAEKPYFMSKNLMKILNKKNKQPKTG

Protein

Choline transporter-like protein 4: slc44a4

Gene

SLC44A4

Protein

Choline transporter-like protein 4

Organism

Homo sapiens

Length

710 amino acids

Function

Isoform 3: Has also thiamine pyrophosphate transporter activity.

Similarity

Belongs to the CTL (choline transporter-like) family.

Mass

79.254 kDa

Sequence

MGGKQRDEDDEAYGKPVKYDPSFRGPIKNRSCTDVICCVLFLLFILGYIVVGIVAWLYGDPRQVLYPRNSTGAYCGMGENKDKPYLLYFNIFSCILSSNIISVAENGLQCPTPQVCVSSCPEDPWTVGKNEFSQTVGEVFYTKNRNFCLPGVPWNMTVITSLQQELCPSFLLPSAPALGRCFPWTNVTPPALPGITNDTTIQQGISGLIDSLNARDISVKIFEDFAQSWYWILVALGVALVLSLLFILLLRLVAGPLVLVLILGVLGVLAYGIYYCWEEYRVLRDKGASISQLGFTTNLSAYQSVQETWLAALIVLAVLEAILLLMLIFLRQRIRIAIALLKEASKAVGQMMSTMFYPLVTFVLLLICIAYWAMTALYLATSGQPQYVLWASNISSPGCEKVPINTSCNPTAHLVNSSCPGLMCVFQGYSSKGLIQRSVFNLQIYGVLGLFWTLNWVLALGQCVLAGAFASFYWAFHKPQDIPTFPLISAFIRTLRYHTGSLAFGALILTLVQIARVILEYIDHKLRGVQNPVARCIMCCFKCCLWCLEKFIKFLNRNAYIMIAIYGKNFCVSAKNAFMLLMRNIVRVVVLDKVTDLLLFFGKLLVVGGVGVLSFFFFSGRIPGLGKDFKSPHLNYYWLPIMTSILGAYVIASGFFSVFGMCVDTLFLCFLEDLERNNGSLDRPYYMSKSLLKILGKKNEAPPDNKKRKK

Protein

Choline transporter-like protein 4: SLC44A4

Gene

SLC44A4

Protein

Choline transporter-like protein 4

Organism

Bos taurus

Length

707 amino acids

Function

Choline transporter that plays a role in the choline-acetylcholine system and is required to the efferent innervation of hair cells in the olivocochlear bundle for the maintenance of physiological function of outer hair cells and the protection of hair cells from acoustic injury (By similarity). Also described as a thiamine pyrophosphate transporter in colon, may mediate the absorption of microbiota-generated thiamine pyrophosphate and contribute to host thiamine (vitamin B1) homeostasis (By similarity).

Similarity

Belongs to the CTL (choline transporter-like) family.

Mass

78.938 kDa

Sequence

MGGKQDQDKEAYGKPAKYDPSFRGPIRNRSCTDIICCVLFFLFILGYIAVGILAWVYGDPKQVLYPRNSTGAYCGIGENKEKPYLLYFNIFSCVLNTNIIAIAQNGLKCPTPQVCVSSCPEASWTVEPRQFSQTVEQVFYAANRNFCLPGVPGNMQVLQSLQQELCPSFLLPSTPALGRCFPWTNSTVPELPGISNTSISQSISGLLDSLNARDISVKIFEDFAQSWYWILIALGLALVLSLLFILLLRLVAGPLVFVLIIGVLGVLAYGIYHCWEEYRVLRDKGASISQLGFTTNLSAYRNVQETWLAALIILAVLEGVLLLMLIFLRQRICIAIALLKEASRAVGYIMSTMFYPLVTFALLLVCIAYWAIIALFLATSGQPQYVFWAPNSSLPGCEKVPMNTSCDPMEQVNSSCPGLMCVFQGYQSTGLAQRSLFNLQIYAVLGLFWTINWVLALGQCVLAGAFASFYWAFHKPRDIPTFPLGSAFLRTLRYHTGSLAFGALILTLVQIARVILEYIDHKLRGAQNPLTRCILCCFKCCLWCLEKFIKFLNRNAYIMIAIYGKNFCVSAKNAFMLLMRNIVRVVVLDKVTDLLLFFGKLLVVGGVGVLSFFFFTGRIPSLGKTFENPQLNYYWLPIMVSILGAYLIASGFFSVFGMCVDTLFLCFLEDLERNDGSADRPYYMSKSLLKILGKKNKGTPGDKKRKK

Protein

Choline transporter-like protein 4: SLC44A4

Gene

Slc44a4

Protein

Choline transporter-like protein 4

Organism

Mus musculus

Length

707 amino acids

Function

Similarity

Belongs to the CTL (choline transporter-like) family.

Mass

78.723 kDa

Sequence

MGRKQNENEAHGNSAKYDPSFRGPIKNRGCTDIICCVLFLIFILGYIIVGLVAWVYGDPRQVLYPRNSTGAYCGVGDNKDKPYVLYFDILSCAAAINIISIAENGLQCPTPQVCVSSCPLAPWAVEVFQFSKTVGEVYGERRNFCLPAVSPDMIVEESLQKGLCPRFLLPSTPALGRCFPLPNINFTLPEDLRINNTTVSNGISGLLDSINARDVSVKIFEDFAQSWYWILVALGVALALSLLFILLLRLVAAPLVLLLIVGVLAVLAYGIYHCWQQYQVFRDKGASITQLGFTTNFSAYQSVKETWLAALIVLAVLEGILLLMLIFLRQRIRIAIALLKEASRAVGQMMSTMFYPLVTFVLLVICIGYWAVTALYLATSGQPQYIYWASNTSTPGCENVPVNMTCDPMAPLNSSCPNLKCVFKGYSTTGLAQRSLFNLQIYGVLGLFWTVNWVLALGQCVLAGAFASFYWAFHKPRDIPTFPLSSAFIRTLRYHTGSLAFGALILSLVQIARVILEYIDHKLRGSQNPVARCIICCFKCCLWCLEKFIKFLNRNAYIMIAIYGKNFCVSAKNAFMLLMRNVLRVVVLDKVTDLLLFFGKLLVVGGVGVLSFFFFSGRIKGLGKDFENPNLNYYWLPIMTSIMGAYVIASGFFSVFGMCVDTLFLCFLEDLERNDGSQERPYYMPKALLKILGKKNEAPTGGKTRKK

Protein

Choline transporter-like protein 4: Slc44a4

Gene

SLC44A4

Protein

Choline transporter-like protein 4

Organism

Sus scrofa

Length

707 amino acids

Function

Similarity

Belongs to the CTL (choline transporter-like) family.

Mass

78.48 kDa

Sequence

MGEKQDPDKAYGKPAKYDPSFRGPIRNRSCTDIICCVLFFVFILGYIAVGLVAWVYGDPQQVLYPRNSSGAYCGIGENKDKPYLLYFNIFSCVLTTNIIAVAQNGLDCPTPQVCVSSCPAVSWTVATNQLSQTVGQVFYAANRSFCLPGVPGDMPVHQSLSQELCPSFLLPSSPALGRCFPWPNSTVPEVPEISNTSISQGISGLLDSLNARDISVKIFEDFAQSWYWILAALGVALVLSLLFVLLLRLVAGPLVFVLIIGVLGVLAYGIYHCWNEYRLLRDKGASISQLGFTTNLSAYSSVQETWLAALILLAVLEGILLLMLIFLRQRIRIAIALLEEASRAVGQMMSTLFYPLVTFVLLLVCIAYWAMTALYLATSGQPQYVLWAPNVSLAGCEKVMMNTSCDPMNQPVNSTCPGLMCVFQGYLSTGLVQRSLFNLQIYGVLGLFWTINWVLALGQCVLAGAFASFYWAFHKPRDIPTFPLSSAFIRTLRYHTGSLAFGALILTLVQIARAILEYIDHKLRGAQNPVARCIMCCFKCCLWCLEKFIKFLNRNAYIMIAIYGKNFCVSAKNAFMLLMRNIVRVVVLDKVTDLLLFFGKLLVVGGVGVLSFFFFTGRIQGLGKDFESPQLNYYWLPIMTSIMGAYVIASGFFSVFGMCVDTLFLCFLEDLERNDGSLDRPYYMSKALLKILGKKNEVPSGDKKRKK

Protein

Choline transporter-like protein 4: SLC44A4

Gene

Slc44a4

Protein

Choline transporter-like protein 4

Organism

Rattus norvegicus

Length

707 amino acids

Function

Similarity

Belongs to the CTL (choline transporter-like) family.

Mass

78.737 kDa

Sequence

MGKKQKENEAYGNSAKYDPSFRGPIKNRGCTDIICCVLFLVFILGYIVVGLVAWVYGDPRQVLYPRNSTGAYCGVGDNKDKPYVLYFNILSCAAAINVISIAENGLQCPTPQVCVSSCPQTPWVVEGFQLSNTVGDVYKEYRNFCVPAVSPDMVVMDSLQKGLCPSFLLPSTPALGRCFPLPNINFTLPEQLQINNTTVSKGISGLLDSINARDVSVKIFEDFAQSWYWILVALGVALVLSLLFILLLRLVAAPLVLLLIVGVLAVLAYGIYHCWQQYRELRDQGVSITQLGFTANLSAYQNVKETWLAALIILAVLEGVLLLMLIFLRQRIRIAIALLKEASRAVGQMMSTMFYPLVTFVLLVICIGYWAVTALYLATSGQPQYVYWVHNTSTPGCEKVLVNVSCDPMAPLNSSCPELKCTFTGYSSSGLAQRSLFNLQIYGILGLFWTVNWVLALGQCVLAGAFASFYWAFHKPRDIPTFPLSSAFIRTLRYHTGSLAFGALILTLVQIARVILEYIDHKLRGSQNPVARCIICCFKCCLWCLEKFIKFLNRNAYIMIAIYGKNFCVSAKNAFMLLMRNVVRVVVLDKVTDLLLFFGKLLVVGGVGVLSFFFFSGRIKGLGKDFKNPDLNYYWLPIMTSIMGAYVIASGFFSVFGMCVDTLFLCFLEDLERNDGSQERPYYMPKALLKILGKKNEVPTGGKNRKK

Protein

Choline transporter-like protein 4: Slc44a4

Gene

slc44a4

Protein

Choline transporter-like protein 4

Organism

Xenopus laevis

Length

707 amino acids

Function

Similarity

Belongs to the CTL (choline transporter-like) family.

Mass

79.32 kDa

Sequence

MASEEYGEPAKHDPSFKGPIKKRGCTDIICCVLFMVFLLGYMVVGILAWLYGDPRQVIYPRNSTGMYCGIGENQGKPNVLYYDLLKCVTGTNILAAAMNGLQCPTTQVCVATCPMDFKWALPNGSPASVYIQEYCQPSINLTTTPLTVAQIAAKELCPVFLVPSTSFFNRCFPGSNLTFPSDFTINGLTANQSRANISEAASQILDSFNFQNVGKKIFEDFAKSWPWIITALVIAMVVSLLFLILLRFTAGILVWVLIVGVIGVIGYGIYHCYMEYDTLNKQGVSVSDVGFTFNLGVYFRVKETWLAILIVLAVVEAILLLVLLFLRKRILIAIALIKEASKAIGHIMSSLFYPLVTFVLLVVCVAYWGMTALYLATSGAPIYRISTVNTSVPGCENITGNETCNPMTFKPSSSCNEARCIFYRYNNEGLFQTNLFNLQIYNVIGFLWCINFVIALGQCVLAGAFASYYWAFHKPKDIPFFPVAESFMRTLRYHTGSLAFGSLILTIVQLIRIILEYVDHKLKGAQNPCTRFLLCCLKCCFWCLEKFIKFLNRNAYIMIAVYGKNFCVSAKNAFKLLMRNIVRVVVLDKVTDLLIFFGKLIVVGGVGVLAFFFFSGRIPIPNDSFKSPTLNYYWIPIITVVLGSYMIAHGFFSVYNMCVDTLFLCFLEDLERNDGSQEKPYYMSKSLMSILNKKNRPPKSEEKKKKK

Protein

Choline transporter-like protein 4: slc44a4