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SLC30A7

Gene
slc30a7
Protein
Zinc transporter 7
Organism
Xenopus tropicalis
Length
390 amino acids
Function
Seems to facilitate zinc transport from the cytoplasm into the Golgi apparatus. Partly regulates cellular zinc homeostasis (By similarity).
Similarity
Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily.
Mass
43.064 kDa
Sequence
MLPLSIKDDEYKPPKFNLVRKVSGWIRSIFSDTTSRNLFCFLCLNLSFAFVELFYGIWSNSLGLISDSFHMFFDCTALLAGLAASVISRWKTNEAFSYGYVRAEVLAGFVNGLFLIFTAFFIFSEGIERALDTPEVHHERLLPVSILGFLVNLIGIFVFQHGGGHGHSHESGHGHSHSLFNGSLSHGHSHSHGGSHGHSHGGGHGHSHSHGEGHGHSHDQSHKHGHGYGSSCHDEPPEEHTGSSKQILEGVFLHIVADALGSVGVIISTILMQRYGLMIADPICSMLIALLIFVSVIPLLKQSIGILMQRTPPSLDHVLPQCYQRVQQLQGVYHLQEPHFWTLCTDVYIGTLKLVIGPEADARWILSQTHNIFTQAGVRQLYVQIDMAAM

Gene
slc30a7
Protein
Zinc transporter 7
Organism
Danio rerio
Length
387 amino acids
Function
Seems to facilitate zinc transport from the cytoplasm into the Golgi apparatus. Partly regulates cellular zinc homeostasis (By similarity).
Similarity
Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily.
Mass
42.568 kDa
Sequence
MLPLSIKDDEYKPAKFNLVVKLSGWFRSILADKTSRNLFFFLCLNLSFAFVELLYGIWSNSLGLISDSFHMFFDCTALLAGLAASVISRWRSNDSFSYGYVRAEVLAGFVNGLFLIFTAFFIFSEGVERALEPPDVHHDRLLPVSIAGLLVNLVGIFVFQHGGHGHSHGGDDHGHSHSLFNGSAAHGHSHGGHGHSHGGHGHSHESKHGHDHGHSHGGHGHSHDDQHCHDDHTLTPGKGSSKQILQGVFLHIVADTLGSVGVIISAILMQKYDLMIADPICSMLIALLIGVSVVPLLRESIGILMQRTPPSLDHALPECYQRVQQLQGVYNLQEPHFWTLCTDVYIGTLKLLVAPDADSRWILSQTHNIFTQVGVRQLYVQIEVAAM

Gene
SLC30A7
Protein
Zinc transporter 7
Organism
Gallus gallus
Length
378 amino acids
Function
Seems to facilitate zinc transport from the cytoplasm into the Golgi apparatus. Partly regulates cellular zinc homeostasis (By similarity). Required with ZNT5 for the activation of zinc-requiring enzymes, alkaline phosphatases (ALPs). Transports zinc into the lumens of the Golgi apparatus and the vesicular compartments where ALPs locate, thus, converting apoALPs to holoALPs. Required with ZNT5 and ZNT6 for the activation of TNAP.
Similarity
Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily.
Mass
41.989 kDa
Sequence
MLPLSIKDDEYKPPRLNLFRKMSGWFRSILADKTSRNLFFFLCLNLSFAFVELLYGVWSNSLGLISDSFHMFFDCTALLAGLAASVISKWRSNDAFSYGYVRAEVLAGFVNGLFLIFTAFFIFSEGVERALEPPDVHHERLLPVSILGFIVNLIGIFVFQHGGHGHSHGSGHEHSHSLFNGGLSHGHSHRGHGHSHEHKHGHTHDHGHSHGLSHGQDYCHDDHCLEGMTGSSKQILQGVFLHIVADTLGSIGVIISAILMQNYGLMIADPICSMLIALLIGVSIVPLLKESIGILMQRTPPSLENALPQCYQRVQQLQGVYSLHDPHFWTLCTDVYIGTLKLLVAPDADGRWILSQTHNIFTQAGVRQLYIQIDVAAM

Gene
Slc30a7
Protein
Zinc transporter 7
Organism
Mus musculus
Length
378 amino acids
Function
Seems to facilitate zinc transport from the cytoplasm into the Golgi apparatus. Partly regulates cellular zinc homeostasis. Required with ZNT5 for the activation of zinc-requiring enzymes, alkaline phosphatases (ALPs). Transports zinc into the lumens of the Golgi apparatus and the vesicular compartments where ALPs locate, thus, converting apoALPs to holoALPs. Required with ZNT5 and ZNT6 for the activation of TNAP (By similarity).
Similarity
Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily.
Mass
41.79 kDa
Sequence
MLPLSIKDDEYKPPKFNLFGKISGWFRSILSDKTSRNLFFFLCLNLSFAFVELLYGIWSNCLGLISDSFHMFFDSTAILAGLAASVISKWRDNDAFSYGYVRAEVLAGFVNGLFLIFTAFFIFSEGVERALAPPDVHHERLLLVSILGFVVNLVGIFVFNHGGHGHSHGSGHGHSHSLFNGALDHSHGHEDHCHSHEAKHGAAHSHDHDHAHGHGHLHSHDGPSFKATAGPSRQILQGVFLHILADTLGSIGVIASAIMMQNFGLMIADPICSILIAILIVVSVIPLLRESVGILMQRTPPSLENTLPQCYQRVQQLQGVYNLQEQHFWTLCSDVYVGTLKLVVAPDADARWILSQTHNIFTQAGVRQLYVQIDFAAM

Gene
Slc30a7
Protein
Zinc transporter 7
Organism
Rattus norvegicus
Length
378 amino acids
Function
Seems to facilitate zinc transport from the cytoplasm into the Golgi apparatus. Partly regulates cellular zinc homeostasis. Required with ZNT5 for the activation of zinc-requiring enzymes, alkaline phosphatases (ALPs). Transports zinc into the lumens of the Golgi apparatus and the vesicular compartments where ALPs locate, thus, converting apoALPs to holoALPs. Required with ZNT5 and ZNT6 for the activation of TNAP (By similarity).
Similarity
Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily.
Mass
41.774 kDa
Sequence
MLPLSIKDDEYKPPKFNLFGKISGWFRSILSDKTSRNLFFFLCLNLSFAFVELLYGIWSNCLGLISDSFHMFFDSTAILAGLAASVISKWRDNDAFSYGYVRAEVLAGFVNGLFLIFTAFFIFSEGVERALAPPDVHHERLLLVSILGFVVNLVGIFVFNHGGHGHSHGSGHGHSHSLFNGALDHSHGHEDHCHSHGAKHGGAHSHDHDHAHGHGHLHSHDGPSFKETAGPSRQILQGVFLHILADTLGSIGVIASAIMMQNFGLMIADPICSILIAILIVVSVIPLLRESIGILMQRTPPSLENVLPQCYQRVQQLQGVYNLQEQHFWTLCSDVYVGTLKLVVAPDADARWILSQTHNIFTQAGVRQLYVQIDFAAM

Gene
SLC30A7
Protein
Zinc transporter 7
Organism
Bos taurus
Length
376 amino acids
Function
Seems to facilitate zinc transport from the cytoplasm into the Golgi apparatus. Partly regulates cellular zinc homeostasis. Required with ZNT5 for the activation of zinc-requiring enzymes, alkaline phosphatases (ALPs). Transports zinc into the lumens of the Golgi apparatus and the vesicular compartments where ALPs locate, thus, converting apoALPs to holoALPs. Required with ZNT5 and ZNT6 for the activation of TNAP (By similarity).
Similarity
Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily.
Mass
41.745 kDa
Sequence
MLPLSIKDDEYKPPKFNLFRKISGWFRSILSDKTSRNLFFFLCLNLSFAFVELLYGIWSNCLGLISDSFHMFFDSTAILAGLAASVISKWRDNDAFSYGYVRAEVLAGFVNGLFLIFTAFFIFSEGVERALAPPDVHHERLLLVSILGFVVNLVGIFVFKHGGHGHSHGSGHGHSHSLFNGALDQTHGHGDHCHSHELKHGAAHSHDHAHGHGHFHSHDGPSLKETTGPSRQILQGVFLHILADTLGSIGVIASAIMMQNFGLMIADPICSILIAMLIVISVIPLLRESVGILMQRTPPLLENTLPQCYQRVQQLQGVYSLQEQHFWTLCSDVYVGTLKLVVAPDADARWILSQTHNIFTQAGVRQLYVQIDFAAM

Gene
SLC30A7
Protein
Zinc transporter 7
Organism
Homo sapiens
Length
376 amino acids
Function
Seems to facilitate zinc transport from the cytoplasm into the Golgi apparatus. Partly regulates cellular zinc homeostasis. Required with ZNT5 for the activation of zinc-requiring enzymes, alkaline phosphatases (ALPs). Transports zinc into the lumens of the Golgi apparatus and the vesicular compartments where ALPs locate, thus, converting apoALPs to holoALPs. Required with ZNT5 and ZNT6 for the activation of TNAP (By similarity).
Similarity
Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily.
Mass
41.626 kDa
Sequence
MLPLSIKDDEYKPPKFNLFGKISGWFRSILSDKTSRNLFFFLCLNLSFAFVELLYGIWSNCLGLISDSFHMFFDSTAILAGLAASVISKWRDNDAFSYGYVRAEVLAGFVNGLFLIFTAFFIFSEGVERALAPPDVHHERLLLVSILGFVVNLIGIFVFKHGGHGHSHGSGHGHSHSLFNGALDQAHGHVDHCHSHEVKHGAAHSHDHAHGHGHFHSHDGPSLKETTGPSRQILQGVFLHILADTLGSIGVIASAIMMQNFGLMIADPICSILIAILIVVSVIPLLRESVGILMQRTPPLLENSLPQCYQRVQQLQGVYSLQEQHFWTLCSDVYVGTLKLIVAPDADARWILSQTHNIFTQAGVRQLYVQIDFAAM