SLC19A3

Gene

SLC19A3

Protein

Thiamine transporter 2

Organism

Homo sapiens

Length

496 amino acids

Function

Mediates high affinity thiamine uptake, probably via a proton anti-port mechanism. Has no folate transport activity.

Similarity

Belongs to the reduced folate carrier (RFC) transporter (TC 2.A.48) family.

Mass

55.665 kDa

Sequence

MDCYRTSLSSSWIYPTVILCLFGFFSMMRPSEPFLIPYLSGPDKNLTSAEITNEIFPVWTYSYLVLLLPVFVLTDYVRYKPVIILQGISFIITWLLLLFGQGVKTMQVVEFFYGMVTAAEVAYYAYIYSVVSPEHYQRVSGYCRSVTLAAYTAGSVLAQLLVSLANMSYFYLNVISLASVSVAFLFSLFLPMPKKSMFFHAKPSREIKKSSSVNPVLEETHEGEAPGCEEQKPTSEILSTSGKLNKGQLNSLKPSNVTVDVFVQWFQDLKECYSSKRLFYWSLWWAFATAGFNQVLNYVQILWDYKAPSQDSSIYNGAVEAIATFGGAVAAFAVGYVKVNWDLLGELALVVFSVVNAGSLFLMHYTANIWACYAGYLIFKSSYMLLITIAVFQIAVNLNVERYALVFGINTFIALVIQTIMTVIVVDQRGLNLPVSIQFLVYGSYFAVIAGIFLMRSMYITYSTKSQKDVQSPAPSENPDVSHPEEESNIIMSTKL

Protein

Thiamine transporter 2: SLC19A3

Gene

SLC19A3

Protein

Thiamine transporter 2

Organism

Macaca fascicularis

Length

496 amino acids

Function

Mediates high affinity thiamine uptake, probably via a proton anti-port mechanism. Has no folate transport activity (By similarity).

Similarity

Belongs to the reduced folate carrier (RFC) transporter (TC 2.A.48) family.

Mass

55.87 kDa

Sequence

MDCYRTSPSNSWIYTTVILCIFGFFSMMRPSEPFLIPYLSGPDKNLTSEEMTNEIFPVWTYSYLVLLLPVLVLTDYVRYKPVIILQGISFIITWLLLLFGQGVKTMQVVEFFYGMVTATEVAYYAYIYSVVSPEHYQRVSGYCRSVTLVAYTAGSVLAQLLVSLANLSYFYLNVISLASVSVAFLFSLFLPMPKKSMFFHAKPSREIKKSSSVNPVLEETHEGEAPDCEKQKPTSEIPSTSGKLHKGQLNSLKPRNVTVEVFVQWFQDLKECYSSKRLFYWSLWWAFATAGFNQILNYVQILWDYKSPSQDSSIYNGAVEATATFGGAVAAFAVGYVKVNWDLLGELALAVFSVVNAGSLFLMHYTANIWACYAGYLIFKSSYMLLITIAVFQIAVNLSVERYALVFGINTFIALVIQTIITVIVVDQRGLNLPISIQFLVYGSYFAVIAGIFLMRSMYIIYSTKSQKDVQSPAPSENPDMSHPEEESNAIMSTKL

Protein

Thiamine transporter 2: SLC19A3

Gene

Slc19a3

Protein

Thiamine transporter 2

Organism

Mus musculus

Length

488 amino acids

Function

Mediates high affinity thiamine uptake, probably via a proton anti-port mechanism. Has no folate transport activity (By similarity).

Similarity

Belongs to the reduced folate carrier (RFC) transporter (TC 2.A.48) family.

Mass

55.073 kDa

Sequence

MDSSCRTPPSNSWVYPTVILCLFGFFSMFRPSEAFLIPFLSEPSKNLTSPEMTNEILPVWTYSYLATLPPVFVLTDYLRYKPVIMLHVVAFATSYLFLLFGQGVMLMQTAEFFFGVVSATEIAYFAYIYSMVSPEHYQKVSSYCRSITLVAYTAGSVLAQLLVSLTNLPYSSLFYISLACVSVAFFFSLFLPMPKKSMFFHAKSDRDDCPKPLEQCTVPKEAQSNRTHSELFANSKNLEDREMSNPDPENSALRHFAHWFQDLKECYSSKHLVYWSLWWAFATAGYNQILNYVQVLWEHKAPSQDSSIYNGAVEAIATFGGALASFSVGYLKVNWDLLGELGLAVFSAVIAGSLFLMNYSRSIWVCYAGYLLVKSSYSFLITIAVFQIAVNLSLERYALVFGIDTFIALVIQTIMTMIVVDQRGLQLPVTTQFLVYGSYFAVIAGVFLMRSIYILCSAKCRKEVQNLATTRSPNEPHPQEPSNVSTKF

Protein

Thiamine transporter 2: Slc19a3