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SKN7

Gene
SKN7
Protein
Transcription factor SKN7
Organism
Chaetomium thermophilum (strain DSM 1495 / CBS 144.50 / IMI 039719)
Length
765 amino acids
Function
Transcription factor that is part of a SLN1-YPD1-SKN7 two-component regulatory system, which controls gene expression in response to changes in the osmolarity of the extracellular environment. Under low osmotic conditions, phosphorylated and activated by the phosphorelay intermediate protein YPD1. Also activated in response to oxidative stress, independent on the two-component regulatory system. Regulates heat shock genes in response to oxidative stress and genes involved in cell wall integrity in response to osmotic changes.
Similarity
Belongs to the SKN7 family.
Mass
81.456 kDa
Sequence
MPPTNGEGGSQQPQQQQQQQQQQQQQQQQQQQQQQGGSGSSDFVRKLYKMLEDPSYHSVVRWSDDGDSFVVLENEKFTKTILPKHFKHSNFASFVRQLNKYDFHKVRHNDENGESPYGRDAWEFKHPEFRADRKDNLDNIRRKAPAPRKQQQSEEAFNASQQQIAALSESLQATQQQLQALQQQCYELEKTNRLLVSEVMTLQKMVKAQNQASNEIINHLGSMEDRRRNNRGATQAAPNFHAGAMSFLTDGAEEPAPELRRARELLSVVGPDLQANRELERLYMTYNQNGAPAEPAATNSSAVMFTQAAAPGTQATAPGMPLVHNPLNDPQNMMYPVAQTPSIDPSFHTDQMHNMPYSRPLSNPAVVAETSSSQITPSQITPPPKDQMSSMWRDKKPRVLLVEDDKTCARIGAKFLSTLDCGVDTAGDGLEAVERINQDSTRFDLIFMDIIMPNMDGVSATAMIRMVSPHVPIIAMTSNIRGEDINTYFQYGMNDVLAKPFTRDNMSRLLRRHLAHLLKDPQSAASTGIVLTTDDLTLAGQTAGPATTGVGVGVAGAPSGGAHGPGPPAQHQQGYAMAPPTTMQPAPPQVKFEQSPTAAPAPGLDPSSAAAAPTWQSTNPAGVQLQPPPPPTPTQPSPTSAAPPAGLDPASAVAAAAAAAAAAAAAAASMTPGGYLAAAPPPPPPPGAMVLTPAGTPTGVGHPAPSGAGSAAGARGPPGPGPVGPGSVVDDSRPEKRQRLMQGGYASVSGHGHGHPGVGVAGFVQ

Gene
SKN7
Protein
Transcription factor SKN7
Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
Length
622 amino acids
Function
Transcription factor that is part of a SLN1-YPD1-SKN7 two-component regulatory system, which controls gene expression in response to changes in the osmolarity of the extracellular environment. Under low osmotic conditions, phosphorylated and activated by the phosphorelay intermediate protein YPD1. Also activated in response to oxidative stress, independent on the two-component regulatory system. Regulates heat shock genes in response to oxidative stress and genes involved in cell wall integrity in response to osmotic changes.
Similarity
Belongs to the SKN7 family.
Mass
69.202 kDa
Sequence
MSFSTINSNVNKTTGDSNNNTTENSSTADLLGMDLLQSGPRLMNTMQPNNSSDMLHINNKTNNVQQPAGNTNISSANAGAKAPANEFVRKLFRILENNEYPDIVTWTENGKSFVVLDTGKFTTHILPNHFKHSNFASFVRQLNKYDFHKVKRSPEERQRCKYGEQSWEFQHPEFRVHYGKGLDNIKRKIPAQRKVLLDESQKALLHFNSEGTNPNNPSGSLLNESTTELLLSNTVSKDAFGNLRRRVDKLQKELDMSKMESYATKVELQKLNSKYNTVIESLITFKTINENLLNNFNTLCSTLANNGIEVPIFGDNGNRNPTGNTNPATTTAIQSNNNTNNASPATSTVSLQLPNLPDQNSLTPNAQNNTVTLRKGFHVLLVEDDAVSIQLCSKFLRKYGCTVQVVSDGLSAISTLEKYRYDLVLMDIVMPNLDGATATSIVRSFDNETPIIAMTGNIMNQDLITYLQHGMNDILAKPFTRDDLHSILIRYLKDRIPLCEQQLPPRNSSPQTHSNTNTANSNPNTINEQSLAMLPQDNPSTTTPVTPGASISSAQHVQQGQQEQQHQIFHAQQQQQHHNAIANARSDVAIPNLEHEINTVPHSSMGSTPQLPQSTLQENQLS

Gene
SKN7
Protein
Transcription factor SKN7
Organism
Candida albicans (strain SC5314 / ATCC MYA-2876)
Length
559 amino acids
Function
Transcription factor that is part of a SLN1-YPD1-SKN7 two-component regulatory system, which controls gene expression in response to changes in the osmolarity of the extracellular environment. Under low osmotic conditions, phosphorylated and activated by the phosphorelay intermediate protein YPD1. Also activated in response to oxidative stress, independent on the two-component regulatory system. Regulates heat shock genes in response to oxidative stress and genes involved in cell wall integrity in response to osmotic changes.
Similarity
Belongs to the SKN7 family.
Mass
61.058 kDa
Sequence
MSSLQQPIPPNSTLATTASSNQSGSNDFVKKLFLMLQEDSYKEVVRWTVKGDSFVVINTNEFTKDILPKHFKHSNFASFVRQLNKYDFHKVKISNEAKASYPYGEDAWEFKHPEFRINDAEALENIKRKGPTAKKSASNVTIKTEANNNGTQPTCNHNYSQLVSATNHLKEQVESLKNDKHSLYQEISVLERKYKTVVENIVAINTFNERYYRSMNVLINSIVQNGMKLPPLDFPPPVQLGPDSGIGSNLGPISSDTALPSISHHLSSPLPHHQQLLNRTIRPISSPIDGIPLVKLQQQSLGQNLQAPIGTPSAVPFSEEASSSIQAATPAPLAQPVAQPINQPPPPPPPPATQQQPLPPPPPPATATSQIPSAPPPPTQQQVGTSSSSVPTISPKSQGIVVSNSASPTTSAQISTTSVPNPKFHVLLVEDDNVCIQLCRKFLVKYGCSVTVVTDGLNAISTVEHTKYDLVLMDIVMPNLDGATATSVIRSFDTKTPIIAMTGNIEDNDLVTYLQNGMSDILAKPFTKDDLYAILSKHLLDPKENKQDNEPTVKKQKLS