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SHS1

Gene
SHS1
Protein
Shionone synthase
Organism
Aster tataricus
Length
761 amino acids
Function
Oxidosqualene cyclase involved in the production of shionone, a triterpenoid with a rare 6/6/6/6 tetracyclic skeleton and a C-3 carbonyl carbon. Produces also small amounts of beta-amyrin, friedelin, dammara-20,24-dienol, and 4-epishionone.
Similarity
Belongs to the terpene cyclase/mutase family.
Mass
87.565 kDa
Sequence
MWRLKIADGGNNPYLYSTNNFIGRQTWEFDPNYGTPEERDEVEQARLHFWNHRHEIKPSGDTLWRMQFIREKKFKQTIPQVKIEDDEEISYDKVTATMRRSVHLLEALLADDGHWPAENSGPSFFIQPLVMCLYITGHLNSVFPAEHRKEILRYVYSHQNKDGGWGLHMEGHSIMFGTTLSYICMRLLGEGPDGGLNGACTRARKWILDHGGAIANPSWGKVWLSILGVHEWVGCNPLPPEFWLFPSFLPMSPGKMWSYCRLVFMPMSYLYGRRFVGPITPLVLQLRKELYAQPYNDIKWKSSRHVCAKEDIYYPHPLLQDLMWDSLYILTEPLLTRWPFNKLRKKALATTMRHIHYEDENSRYITIGSVEKILCMLACWDEDPNGVCFKKHLARIPDYIWVAEDGMKMQTFGSQVWDASIGIQALLATELTHDIAPILKKGHEFIKASQVRDNPSGDFKSMYRHISKGSWTFSDQDHGWQLSDCTTIGLTCCLLLSTMPPETVGEKMDPEQLKDAVNVILSLQSENGGLAAWEPAGSSNWLEMLNPIEFIEDIVIEHEYVECTGTGMEALVLFKKLYPKHRTKEVESFLTNAARYLDNTQMPDGSWYGEWGICFTYGTYYALGGLAAIEKTYENCQSIRKAVRFLLKTQGEDGGWGESYRSCAEKIYIPLDGNRSTVVHTAWAMLGLMHSKQEERDPIPLHRAAKLLINSQMENGDFPQQDTTGAFKKNCLLHYPMYRNIYTLWALAQYRKKVLRQPTGI

Gene
SHS1
Protein
Seventh homolog of septin 1
Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
Length
551 amino acids
Function
Septins are GTPases involved in cytokinesis that assemble early in the cell cycle as a patch at the incipient bud site and form a ring approximate 15 min before bud emergence, which transforms into an hour-glass shaped collar of cortical filaments that spans both sides of the mother-bud neck. This collar persists until just before cytokinesis, when it splits into two rings that occupy opposite sides of the neck. The septins at the bud neck serve as a structural scaffold that recruits different components involved in diverse processes at specific stages during the cell cycle. Many proteins bind asymmetrically to the septin collar. The septin assembly is regulated by protein kinases GIN4 and/or CLA4. May act by recruiting MYO1 and HOF1, a protein involved in septation, to the site of cleavage. Septins are also involved in cell morphogenesis, bud site selection, chitin deposition, cell cycle regulation, cell compartmentalization and spore wall formation.
Similarity
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.
Mass
62.63 kDa
Sequence
MSTASTPPINLFRRKKEHKRGITYTMLLCGPAGTGKTAFANNLLETKIFPHKYQYGKSNASISSNPEVKVIAPTKVVSFNSKNGIPSYVSEFDPMRANLEPGITITSTSLELGGNKDQGKPEMNEDDTVFFNLIMTHGIGENLDDSLCSEEVMSYLEQQFDIVLAEETRIKRNPRFEDTRVHVALYFIEPTGHGLREVDVELMKSISKYTNVLPIITRADSFTKEELTQFRKNIMFDVERYNVPIYKFEVDPEDDDLESMEENQALASLQPFAIITSDTRDSEGRYVREYPWGIISIDDDKISDLKVLKNVLFGSHLQEFKDTTQNLLYENYRSEKLSSVANAEEIGPNSTKRQSNAPSLSNFASLISTGQFNSSQTLANNLRADTPRNQVSGNFKENEYEDNGEHDSAENEQEMSPVRQLGREIKQENENLIRSIKTESSPKFLNSPDLPERTKLRNISETVPYVLRHERILARQQKLEELEAQSAKELQKRIQELERKAHELKLREKLINQNKLNGSSSSINSLQQSTRSQIKKNDTYTDLASIASGRD