Function
Plays an essential role in the maturation of presomitic mesoderm cells by individual attenuation of both fgf and wnt signaling. Inhibits both wnt and fgf signaling through the regulation of protein maturation and cell surface transportation of their receptors within the endoplasmic reticulum.
Similarity
Belongs to the shisa family.
Sequence
MWLEGSPLAVLAAVSFLLSVLAAAQGSGEYCHGWLDAQAVWRDGFQCPERFDGDDSTICCGKCELRYCCSSAEARLDQGVCNNDRQQGAPDHNRPDKDSPDSTAVPIYVPFLIVGSVFVAFIIVGSLVAICCCRCLRPKQEPQQSRAPGSNRLMETIPMISSASTSRGSSSRQSSTAASSSSSANSGARPPPTRSQTNCCLPEGAMNNVYVNMPTNFSVLNCQQATQLVQHQGQYLHPQFVGYAVPHDSVPMTPVPQFIDGLQGGYRQMQSPYPHSNPEQMMYPAVTV