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SFR1

Gene
Sfr1
Protein
Swi5-dependent recombination DNA repair protein 1 homolog
Organism
Mus musculus
Length
319 amino acids
Function
Component of the SWI5-SFR1 complex, a complex required for double-strand break repair via homologous recombination (PubMed:20976249). Acts as a transcriptional modulator for ESR1.
Similarity
Belongs to the SFR1/MEI5 family.
Mass
35.183 kDa
Sequence
MAEEGNQEFTSKMENSSDSASTSPDAPQPSENPPSPPTSPAAPQTSENPPSPPTSPAVPQTRENPPSPPTSPAAPQPRENPPSPPTSPAAPQPRENPPSPPTSPAAPQPRENPPSPHSNSSGKQPLSGTPKERLKKARSSSHSFCSVVKRMKVENDENNETLSEPGESSKEENCSKAQESLKNKDSEPGEKSSEEKNTCESKSSDTGSSNALPKESENAIIREKLKQEKIRLIRQVEEKEDLLRRLKLVKMYRIKNDVTELENLIKKWRKCGQRLLCELQSIMSEDEDEKLTLTELIDFYGIDDNLLHYNRSEEEFTGV

Gene
sfr1
Protein
Swi5-dependent recombination DNA repair protein 1
Organism
Schizosaccharomyces pombe (strain 972 / ATCC 24843)
Length
299 amino acids
Function
Involved in DNA recombination repair and meiotic chromosome segregation.
Similarity
Belongs to the SFR1/MEI5 family.
Mass
33.638 kDa
Sequence
MSQTINSELNENATSQCKEDLKVSLSESDLRDSQGQLGIENPPKCNNSGNHSDNLGFIEQSETVHPENEKALTPDLRDTKIHTSLPITTPFSKKRAREAKNILLKPFKSPLRQTASPQVADTNLKPSLAVTNLNSDETNTSSEPVTSPLRTTPNSIKRQKRLFKSPISNCLNPKSDPEITQLLSRRLKLEKEVRNLQEQLITAETARKVEAKNEDKDLQTLIQKWKNAAQQAAEVLFKPMAERIRLAGGVTQSFRIEEGENKGQIQEVRTEFTMSMFLNQFGVPVHLMSFDEENGDWKS

Gene
Sfr1
Protein
Swi5-dependent recombination DNA repair protein 1 homolog
Organism
Rattus norvegicus
Length
251 amino acids
Function
Component of the SWI5-SFR1 complex, a complex required for double-strand break repair via homologous recombination. Acts as a transcriptional modulator for ESR1.
Similarity
Belongs to the SFR1/MEI5 family.
Mass
28.729 kDa
Sequence
MASAPSDIPENAFRLAKASGRCQSMMSQMKDETKCMGAVFSGYPTALWLEYEVSPQPMSGTLKERLKKARASSQPFCSVVKRIKVENEENDQTLSEPGESSKEENCSKAQESLENKDNEPEKESSEDKNTSESKSLDTGSSSVLQKDSTEKTIKQTLKEEKAKLTRQVQEKEDLLRRLKLVKMYRIKNDVTELEDLIKKWRRCGQRLLCELQSIMSEDEDEKLTLTELIDYYGIDDKLLHYNRTEEEFTGV

Gene
SFR1
Protein
Swi5-dependent recombination DNA repair protein 1 homolog
Organism
Homo sapiens
Length
245 amino acids
Function
Component of the SWI5-SFR1 complex, a complex required for double-strand break repair via homologous recombination (PubMed:21252223). Acts as a transcriptional modulator for ESR1 (PubMed:23874500).
Similarity
Belongs to the SFR1/MEI5 family.
Mass
28.262 kDa
Sequence
MAEGEKNQDFTFKMESPSDSAVVLPSTPQASANPSSPYTNSSRKQPMSATLRERLRKTRFSFNSSYNVVKRLKVESEENDQTFSEKPASSTEENCLEFQESFKHIDSEFEENTNLKNTLKNLNVCESQSLDSGSCSALQNEFVSEKLPKQRLNAEKAKLVKQVQEKEDLLRRLKLVKMYRSKNDLSQLQLLIKKWRSCSQLLLYELQSAVSEENKKLSLTQLIDHYGLDDKLLHYNRSEEEFIDV

Gene
SFR1
Protein
Swi5-dependent recombination DNA repair protein 1 homolog
Organism
Gallus gallus
Length
222 amino acids
Function
Component of the SWI5-SFR1 complex, a complex required for double-strand break repair via homologous recombination (By similarity). May act as a transcriptional modulator for ESR1 (By similarity).
Similarity
Belongs to the SFR1/MEI5 family.
Mass
25.176 kDa
Sequence
MEEAACGKLTSLCHTPKDSGTAAPQRTSSGKQPMSATLRERLRKTRRSFTTNFAVAKRLKVDTEEKDCTDVDNRCLPKIGMDCSTLQDGSECLEQNCTVNTYFKSPLQENNLCESAENVVRVDLGQQQSLGEKVRLMKQVKEKEELLRRLKLVKMYRSKNNLSELQALIVKWRSSTQLMLYELQAAFSADGKKVSLSQLIDTFGLEDHLLHYSRAEEDFVDT

Gene
sfr1
Protein
Swi5-dependent recombination DNA repair protein 1 homolog
Organism
Xenopus laevis
Length
213 amino acids
Function
Component of the swi5-sfr1 complex, a complex required for double-strand break repair via homologous recombination (By similarity).
Similarity
Belongs to the SFR1/MEI5 family.
Mass
24.472 kDa
Sequence
MESTSPHQGSFYKSNLCSPDSPKDTVPKQPMSATLRERLRKTRRSFNAAFSVAKRLKVDCEENESSSDCPNNNLPPHEDSEPNATKIEVDLVSEGDICRLDSRTSSEASSPVRCKDHKQLLQEKKLLLKKLEEQEDTLRRLKMVKLYRAKNNLSELQSLIEKWRKSSQLSLYELQAALIAENNKVTLSQLIESYGLDENLLHYNRTEEDFQDQ

Gene
sfr1
Protein
Swi5-dependent recombination DNA repair protein 1 homolog
Organism
Danio rerio
Length
201 amino acids
Function
Component of the swi5-sfr1 complex, a complex required for double-strand break repair via homologous recombination.
Similarity
Belongs to the SFR1/MEI5 family.
Mass
23.066 kDa
Sequence
METTPIKPTAADETTPSAEQSSNRSSTAKPMSASLREKLKRSRHSFKSPLSVVKRLKIEDDTEPQPSQQGEEEKHGVKDDRDSNVTETDVNRNDMKLQRDSNHTAELPSQQCEALRKAVKERTETLRRLKMVKMYRKKNDLNELQRLTDKWRSCAQSVLYELQRELATGGKQASLSQLIDSFGINDKLLHFDRTEEDFTDT