SEMG1

Semenogelin-1

615 amino acids

Predominant protein in semen. It participates in the formation of a gel matrix entrapping the accessory gland secretions and ejaculated spermatozoa. Fragments of semenogelin and/or fragments of the related proteins may contribute to the activation of progressive sperm movements as the gel-forming proteins are fragmented by KLK3/PSA (By similarity).

Belongs to the semenogelin family.

68.118 kDa

MKPIIFLVLSLLLILEKQAAVMGQKGGSKGRLPSESSQFPHGQKGQQYCARKDKQHAESKRSVSIEHTYHVDIPDHDQTRTSKQYDLNAQNKRIKSEKHAAGSQEPFNHKQEGREHGKSKGDFHVLIIHHKRGHAPHGTQNPSQDQGNSTSGKGISSQDSNTKERLLALGLGKEQDSVSGTQRNGTQGGSQSSPVLQTEDPVHNKKPETQNSLQNKGSSPNVNETKQKHSSKVQSPLCSAQEDRLQHGSKDVFSKNQNQTRNPNQDQEHGQKAHNRSCQCSSTEERRPNHGEKGIQKDASKGSTSNQTEDKMHDKSQKQVTTPSQEDGHRANKTSSQSSGTEERRPNHGEKGIQKDASKGSTSNQTEDKMHDKSQKQVTTPSQEDGHRANKTSSQSSGTEERRPNHGEKGIQKDASKGSTSNQTEDKMHDKSQKQVTTPSQEDGHRANKTSSQSSGTEERRPNHGEKGIQKDASKGSTSNKTEDKMHDKSQKQVTTPSQEDGHRANKTSSQSSGTEERRPNHGEKGIQKDASKGSSSNKTEDEKHDKSQKQVTTPSQDQQSGQDADEEEDLLSHYQKDRHQHRSYGGLDIVIVEHEADDDDRLTHHDNNQNSIFT

SEMG1

Semenogelin-1

462 amino acids

Alpha-inhibin-92 and alpha-inhibin-31, derived from the proteolytic degradation of semenogelin, inhibit the secretion of pituitary follicle-stimulating hormone.

Belongs to the semenogelin family.

52.131 kDa

MKPNIIFVLSLLLILEKQAAVMGQKGGSKGRLPSEFSQFPHGQKGQHYSGQKGKQQTESKGSFSIQYTYHVDANDHDQSRKSQQYDLNALHKTTKSQRHLGGSQQLLHNKQEGRDHDKSKGHFHRVVIHHKGGKAHRGTQNPSQDQGNSPSGKGISSQYSNTEERLWVHGLSKEQTSVSGAQKGRKQGGSQSSYVLQTEELVANKQQRETKNSHQNKGHYQNVVEVREEHSSKVQTSLCPAHQDKLQHGSKDIFSTQDELLVYNKNQHQTKNLNQDQQHGRKANKISYQSSSTEERRLHYGENGVQKDVSQSSIYSQTEEKAQGKSQKQITIPSQEQEHSQKANKISYQSSSTEERRLHYGENGVQKDVSQRSIYSQTEKLVAGKSQIQAPNPKQEPWHGENAKGESGQSTNREQDLLSHEQKGRHQHGSHGGLDIVIIEQEDDSDRHLAQHLNNDRNPLFT