SEI2

Seipin-2

526 amino acids

Involved in lipid metabolism and lipid droplet (LD) morphology, number, and size. Supports the formation of small-sized LDs and modulates triacylglycerol accumulation. Induces probably a reorganization of the endoplasmic reticulum into LD-forming domains.

Belongs to the seipin family.

59.677 kDa

MDSESESESNPSTTDEFDRFLDAPDEFYYDCLPIRSNSHQPSSLLRRRKSAHRRDLISSDIETEPSSSSDGFDVGEKSSYVEKNAELRGDIDTSDVIESTKDSIDLSSEKENDLDVISSSGNDMDVIDSGRNRVDPFQEESTVTTVSSDDQGDDDYAGSVPQFREPPNSTEWSLLGFLVGLVIKAIEFQVSFMTSLLTFPPWLLRNCFLFFFDPFSTIRFGRRFLMARVAGISDMIFGYMNPFRLKDTKQMLSIVCKFGWGMFWAVYVGIVLFGLLVSSLMIGGYVINRIADKPFEVKETLNFDYTKNSPEAYVPISSCAGVECEGSCKESNEMSKIRGLRVIPRDQKLDIILSMTLPESAYNKNLGMFQVRVDFLSVDGQTIASIRRPCMLRFRSEPIRLVQTFFKVVPLVTGYVSEIQTLSLKLKGFVEKDIPTACLKIIIEQRAEFRPGAGIPELYDASLSVESGLPFFRKIIWKWRKTLFVWISMSLFITELLFTLVCCRPLIIPRTQPRDRSPSNPTGVWR