Protein
Phosphoglycolate phosphatase
Organism
Shigella dysenteriae serotype 1 (strain Sd197)
Function
Specifically catalyzes the dephosphorylation of 2-phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress.
Similarity
Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family.
Sequence
MNKFEDIRGVAFDLDGTLVDSALGLAAAVDMALYALKLPIAGEERVITWIGNGADVLMERALTWARQERATLRKTMGKPPVDDDIPAEEQVRILRKLFDRYYGEVAEEGTFLFPHVADTLGALQAKGLPLGLVTNKPTPFVAPLLEALDIAKYFSVVIGGDDVQNKKPHPDPLLLVAERMGIAPQQMLFVGDSRNDIQAAKAAGCPSVGLTYGYNYGEAIDLSQPDVIYQSINDLLPALGLPHSENQESKND