Protein
E3 ubiquitin-protein ligase SDIR1
Organism
Arabidopsis thaliana
Function
E3 ubiquitin-protein ligase that acts as a positive regulator of abscisic acid-related stress signal transduction (PubMed:17573536, PubMed:18685183). Interacts with and ubiquitinates ATP1/SDIRIP1 to modulate ATP1/SDIRIP1 stability through the 26S proteasome pathway. Regulates abscisic acid (ABA) and salt stress responses by negatively affecting ATP1/SDIRIP1 stability. The SDIR1-ATP1/SDIRIP1 complex plays an important role in ABA signaling through the ubiquitination pathway (PubMed:25616872).
Sequence
MSFVFRGSRGDLESGFSGGFLPERRAMRVHGARPVNSNSLAFLVTVLLLFMILNSHQMPPNFLLWLVLGVFLMATTLRMYATCQQLQAHAQAQAAAASGLFSHTELRLHVPPSIALATRGRLQGLRLQLALLDREFDDLDYETLRALDSDNVSTTSMSEEEINALPVHKYKVLDPENGCSLAKQASTSSSAEKMLDSANESKKGTEDELTCSVCLEQVTVGEIVRTLPCLHQFHAGCIDPWLRQQGTCPVCKFRAHSGWQEQDEIDDDASDMV