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SCN4B

Gene
SCN4B
Protein
Sodium channel subunit beta-4
Organism
Bos taurus
Length
228 amino acids
Function
Modulates channel gating kinetics. Causes negative shifts in the voltage dependence of activation of certain alpha sodium channels, but does not affect the voltage dependence of inactivation. Modulates the susceptibility of the sodium channel to inhibition by toxic peptides from spider, scorpion, wasp and sea anemone venom (By similarity).
Similarity
Belongs to the sodium channel auxiliary subunit SCN4B (TC 8.A.17) family.
Mass
25.144 kDa
Sequence
MPGARDQGAARARWLGIGLLGLFLLPVSLSLEVSVGKATTIYAVNGTEILLPCTFSSCFGFENLHFWWSYNSSDTYKILIDGTVKNEKSDPKVKLKDDDRITLEGSTKEKMNNISISLKNLEFSDTGKYTCHVKNPKENDFQHQATIFLQVVDKLEEVDNTVTLIILGVVGGVIGLLIFILLVKKFIAFIIKKTQEKKKECLVSSSGNDNTENGLPGSKAEEKAPTKV
Protein
Sodium channel subunit beta-4: SCN4B

Gene
SCN4B
Protein
Sodium channel subunit beta-4
Organism
Homo sapiens
Length
228 amino acids
Function
Modulates channel gating kinetics. Causes negative shifts in the voltage dependence of activation of certain alpha sodium channels, but does not affect the voltage dependence of inactivation. Modulates the susceptibility of the sodium channel to inhibition by toxic peptides from spider, scorpion, wasp and sea anemone venom.
Similarity
Belongs to the sodium channel auxiliary subunit SCN4B (TC 8.A.17) family.
Mass
24.969 kDa
Sequence
MPGAGDGGKAPARWLGTGLLGLFLLPVTLSLEVSVGKATDIYAVNGTEILLPCTFSSCFGFEDLHFRWTYNSSDAFKILIEGTVKNEKSDPKVTLKDDDRITLVGSTKEKMNNISIVLRDLEFSDTGKYTCHVKNPKENNLQHHATIFLQVVDRLEEVDNTVTLIILAVVGGVIGLLILILLIKKLIIFILKKTREKKKECLVSSSGNDNTENGLPGSKAEEKPPSKV
Protein
Sodium channel subunit beta-4: SCN4B

Gene
Scn4b
Protein
Sodium channel subunit beta-4
Organism
Mus musculus
Length
228 amino acids
Function
Modulates channel gating kinetics. Causes negative shifts in the voltage dependence of activation of certain alpha sodium channels, but does not affect the voltage dependence of inactivation. Modulates the susceptibility of the sodium channel to inhibition by toxic peptides from spider, scorpion, wasp and sea anemone venom (By similarity).
Similarity
Belongs to the sodium channel auxiliary subunit SCN4B (TC 8.A.17) family.
Mass
25.192 kDa
Sequence
MSRAGNRGNTQARWLGTGLLGLFLLPMYLSLEVSVGKATTIYAINGSSILLPCTFSSCYGFENLYFKWSYNNSETSRILIDGIVKNDKSDPKVRVKDDDRITLEGSTKEKTNNISILLSDLEFSDTGRYTCFVRNPKEKDLNNSATIFLQVVDKLEKVDNTVTLIILAVVGGVIGLLVCILLLKKLITFILKKTREKKKECLVSSSGNDNTENGLPGSKAEEKPPTKV
Protein
Sodium channel subunit beta-4: Scn4b

Gene
Scn4b
Protein
Sodium channel subunit beta-4
Organism
Rattus norvegicus
Length
228 amino acids
Function
Modulates channel gating kinetics. Causes negative shifts in the voltage dependence of activation of certain alpha sodium channels, but does not affect the voltage dependence of inactivation. Modulates the susceptibility of the sodium channel to inhibition by toxic peptides from spider, scorpion, wasp and sea anemone venom.
Similarity
Belongs to the sodium channel auxiliary subunit SCN4B (TC 8.A.17) family.
Mass
25.247 kDa
Sequence
MSRAGNRGNTQARWLGIGLLGLFLLPMYLSLEVSVGKATTIYAINGSAILLPCTFSSCYGFENLYFRWSYNNSETSRILIDGIVKNDKSDPKVRVKDDDRITLEGSTKEKMNNISILLSDLEFSDTGRYTCFVRNPKEKDLNNSATIFLQVVDKLEEVDNTVTLIILAVVGGVIGLLVCILLLKKLITFILKKTREKKKECLVSSSGNDNTENGLPGSKAEEKPPTKV
Protein
Sodium channel subunit beta-4: Scn4b