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SBDS

Gene
sbds
Protein
Ribosome maturation protein SBDS
Organism
Dictyostelium discoideum
Length
274 amino acids
Function
Required for the assembly of mature ribosomes and ribosome biogenesis. Triggers the GTP-dependent release of ribosome maturation factors from 60S pre-ribosomes in the cytoplasm, thereby activating ribosomes for translation competence by allowing 80S ribosome assembly. Required for normal levels of protein synthesis. May play a role in cellular stress resistance. May play a role in cellular response to DNA damage. May play a role in cell proliferation (By similarity).
Similarity
Belongs to the SDO1/SBDS family.
Mass
30.57 kDa
Sequence
MSIFTPVNNKTLTNIVVVRYKKGAAKFEIACYPSKVQSYRSKIEKDLNEVIQIHRIFTNVSKGIIAKKDELIKAFGTDNEQEIILLILEKGELQVSSKERDNQSEQTFKDIATIVAEKCVNTETQRPIPVSIIEKAMKDVHYSIHPTKSSKQQSLEVIKQISSVIPIQRAQMRLNITIPTKESKTLNRDKLMVLVSKIEEEDRDGGGLSIVCLVDPGSYRKIDELIKQETKGKGFIDIINLAVAKEGETKINETGKSAPTSTTTTTTTTTSSSK
Protein
Ribosome maturation protein SBDS: sbds

Gene
SBDS
Protein
Ribosome maturation protein SBDS
Organism
Bos taurus
Length
250 amino acids
Function
Required for the assembly of mature ribosomes and ribosome biogenesis. Together with EFL1, triggers the GTP-dependent release of EIF6 from 60S pre-ribosomes in the cytoplasm, thereby activating ribosomes for translation competence by allowing 80S ribosome assembly and facilitating EIF6 recycling to the nucleus, where it is required for 60S rRNA processing and nuclear export. Required for normal levels of protein synthesis. May play a role in cellular stress resistance. May play a role in cellular response to DNA damage. May play a role in cell proliferation (By similarity).
Similarity
Belongs to the SDO1/SBDS family.
Mass
28.718 kDa
Sequence
MSIFTPTNQIRLTNVAVVRMKRAGKRFEIACYKNKVVGWRSGVEKDLDEVLQTHSVFVNVSKGQVAKKEDLISAFGTDDQTEICKQILTKGEVQVSDKERHTQLEQMFRDIATIVADKCVNPETKRPYTVILIERAMKDIHYSVKPNKSTKQQALEVIKQLKEKMKIERAHMRLRFILPVNEGKKLKEKLKPLIKVIESEDYGQQLEIVCLIDPGCFREVDELIKKETKGKGSLEVLSLKDVEEGDEKFE
Protein
Ribosome maturation protein SBDS: SBDS

Gene
SBDS
Protein
Ribosome maturation protein SBDS
Organism
Gallus gallus
Length
250 amino acids
Function
Required for the assembly of mature ribosomes and ribosome biogenesis. Together with EFL1, triggers the GTP-dependent release of EIF6 from 60S pre-ribosomes in the cytoplasm, thereby activating ribosomes for translation competence by allowing 80S ribosome assembly and facilitating EIF6 recycling to the nucleus, where it is required for 60S rRNA processing and nuclear export. Required for normal levels of protein synthesis. May play a role in cellular stress resistance. May play a role in cellular response to DNA damage. May play a role in cell proliferation (By similarity).
Similarity
Belongs to the SDO1/SBDS family.
Mass
28.823 kDa
Sequence
MSIFTPTNQIRLTNVAVVRARRAGKRFEIACYRNKVMGWRSGAEKDIDEVLQTHTVFVNVSKGQVAKKEDLVRAFGTDDQTEICKVILSKGELQVSDKERQTQLEQMFRDIATIVADKCVNPETKRPYTVILIERAMKDIHYSVKPNKSTKQQALEVIRQLKETMQIERAHMRLRFILPVKEGKKLKEKLKPLIKVIENEDFHDQLEIVCLIDPGCFREIDELIRSETKGKGTLEVLSLKDVEEGDEKLE
Protein
Ribosome maturation protein SBDS: SBDS

Gene
SBDS
Protein
Ribosome maturation protein SBDS
Organism
Homo sapiens
Length
250 amino acids
Function
Required for the assembly of mature ribosomes and ribosome biogenesis. Together with EFL1, triggers the GTP-dependent release of EIF6 from 60S pre-ribosomes in the cytoplasm, thereby activating ribosomes for translation competence by allowing 80S ribosome assembly and facilitating EIF6 recycling to the nucleus, where it is required for 60S rRNA processing and nuclear export. Required for normal levels of protein synthesis. May play a role in cellular stress resistance. May play a role in cellular response to DNA damage. May play a role in cell proliferation.
Similarity
Belongs to the SDO1/SBDS family.
Mass
28.764 kDa
Sequence
MSIFTPTNQIRLTNVAVVRMKRAGKRFEIACYKNKVVGWRSGVEKDLDEVLQTHSVFVNVSKGQVAKKEDLISAFGTDDQTEICKQILTKGEVQVSDKERHTQLEQMFRDIATIVADKCVNPETKRPYTVILIERAMKDIHYSVKTNKSTKQQALEVIKQLKEKMKIERAHMRLRFILPVNEGKKLKEKLKPLIKVIESEDYGQQLEIVCLIDPGCFREIDELIKKETKGKGSLEVLNLKDVEEGDEKFE
Protein
Ribosome maturation protein SBDS: SBDS

Gene
Sbds
Protein
Ribosome maturation protein SBDS
Organism
Mus musculus
Length
250 amino acids
Function
Required for the assembly of mature ribosomes and ribosome biogenesis. Together with EFL1, triggers the GTP-dependent release of EIF6 from 60S pre-ribosomes in the cytoplasm, thereby activating ribosomes for translation competence by allowing 80S ribosome assembly and facilitating EIF6 recycling to the nucleus, where it is required for 60S rRNA processing and nuclear export. Required for normal levels of protein synthesis. May play a role in cellular stress resistance. May play a role in cellular response to DNA damage. May play a role in cell proliferation (By similarity).
Similarity
Belongs to the SDO1/SBDS family.
Mass
28.781 kDa
Sequence
MSIFTPTNQIRLTNVAVVRMKRGGKRFEIACYKNKVVGWRSGVEKDLDEVLQTHSVFVNVSKGQVAKKEDLISAFGTDDQTEICKQILTKGEVQVSDKERHTQLEQMFRDIATIVADKCVNPETKRPYTVILIERAMKDIHYSVKPNKSTKQQALEVIKQLKEKMKIERAHMRLRFILPVNEGKKLKEKLKPLMKVVESEDYSQQLEIVCLIDPGCFREIDELIKKETKGRGSLEVLSLKDVEEGDEKFE
Protein
Ribosome maturation protein SBDS: Sbds

Gene
SBDS
Protein
Ribosome maturation protein SBDS
Organism
Pongo abelii
Length
250 amino acids
Function
Required for the assembly of mature ribosomes and ribosome biogenesis. Together with EFL1, triggers the GTP-dependent release of EIF6 from 60S pre-ribosomes in the cytoplasm, thereby activating ribosomes for translation competence by allowing 80S ribosome assembly and facilitating EIF6 recycling to the nucleus, where it is required for 60S rRNA processing and nuclear export. Required for normal levels of protein synthesis. May play a role in cellular stress resistance. May play a role in cellular response to DNA damage. May play a role in cell proliferation (By similarity).
Similarity
Belongs to the SDO1/SBDS family.
Mass
28.764 kDa
Sequence
MSIFTPTNQIRLTNVAVVRMKRAGKRFEIACYKNKVVGWRSGVEKDLDEVLQTHSVFVNVSKGQVAKKEDLISAFGTDDQTEICKQILTKGEVQVSDKERHTQLEQMFRDIATIVADKCVNPETKRPYTVILIERAMKDIHYSVKTNKSTKQQALEVIKQLKEKMKIERAHMRLRFILPVNEGKKLKEKLKPLIKVIESEDYGQQLEIVCLIDPGCFREIDELIKKETKGKGSLEVLNLKDVEEGDEKFE
Protein
Ribosome maturation protein SBDS: SBDS

Gene
Sbds
Protein
Ribosome maturation protein SBDS
Organism
Rattus norvegicus
Length
250 amino acids
Function
Required for the assembly of mature ribosomes and ribosome biogenesis. Together with EFL1, triggers the GTP-dependent release of EIF6 from 60S pre-ribosomes in the cytoplasm, thereby activating ribosomes for translation competence by allowing 80S ribosome assembly and facilitating EIF6 recycling to the nucleus, where it is required for 60S rRNA processing and nuclear export. Required for normal levels of protein synthesis. May play a role in cellular stress resistance. May play a role in cellular response to DNA damage. May play a role in cell proliferation (By similarity).
Similarity
Belongs to the SDO1/SBDS family.
Mass
28.752 kDa
Sequence
MSIFTPTNQIRLTNVAVVRMKRGGKRFEIACYKNKVVGWRSGVEKDLDEVLQTHSVFVNVSKGQVAKKEDLISAFGTDDQTEICKQILTKGEVQVSDKERHTQLEQMFRDIATIVADKCVNPETKRPYTVILIERAMKDIHYSVKPNKSTKQQALEVIKQLKEKMKIERAHMRLRFLLPVNEGKKLKEKLKPLMKVVESEDYSQQLEIVCLIDPGCFREIDELIKKETKGKGSLEVLSLKDVEEGDEKFE
Protein
Ribosome maturation protein SBDS: Sbds

Gene
sbds
Protein
Ribosome maturation protein SBDS
Organism
Xenopus laevis
Length
250 amino acids
Function
Required for the assembly of mature ribosomes and ribosome biogenesis. Together with EFL1, triggers the GTP-dependent release of eif6 from 60S pre-ribosomes in the cytoplasm, thereby activating ribosomes for translation competence by allowing 80S ribosome assembly and facilitating eif6 recycling to the nucleus, where it is required for 60S rRNA processing and nuclear export. Required for normal levels of protein synthesis. May play a role in cellular stress resistance. May play a role in cellular response to DNA damage. May play a role in cell proliferation (By similarity).
Similarity
Belongs to the SDO1/SBDS family.
Mass
28.709 kDa
Sequence
MSIFTPTNQIRLTNVAVVRMKKGGKRFEIACYKNKVMSWRSGAEKDLDEVLQTHSVFMNVSKGQGAKKEDLLKAFGTEDQTEICKQILSKGELQVSEKERSTQLEQMFRDIATIVADKCVNPETKRPYTVNLIERAMKDIHYSVKATKSTKQQALDVIKQLKETMQIERAHMRLRFIVPAKDGKKLKEKLKPLIKHIESENFDQELEIVCLIDPGCFREIDELIRCETKGKGTLEVLSLKDVEEGDEKFE
Protein
Ribosome maturation protein SBDS: sbds

Gene
sbds
Protein
Ribosome maturation protein SBDS
Organism
Xenopus tropicalis
Length
250 amino acids
Function
Required for the assembly of mature ribosomes and ribosome biogenesis. Together with EFL1, triggers the GTP-dependent release of eif6 from 60S pre-ribosomes in the cytoplasm, thereby activating ribosomes for translation competence by allowing 80S ribosome assembly and facilitating eif6 recycling to the nucleus, where it is required for 60S rRNA processing and nuclear export. Required for normal levels of protein synthesis. May play a role in cellular stress resistance. May play a role in cellular response to DNA damage. May play a role in cell proliferation (By similarity).
Similarity
Belongs to the SDO1/SBDS family.
Mass
28.738 kDa
Sequence
MSIFTPTNQIRLTNVAVVRMKKGGKRFEIACYKNKVMSWRSGAEKDLDEVLQTHSVFMNVSKGQVAKKEDLLKSFGTEDPTEICKQILSKGELQVSEKERSTQLEQMFRDIATIVADKCVNPETKRPYTVNLIERAMKDIHYSVKATKSTKQQALDVIKQLKETMQIERAHMRLRFILPAKDGKKLKEKLKPLIKHTESENFDQELEIVCLIDPGCFREIDELIRCETKGKGTLEVLSLKDVEEGDEKFE
Protein
Ribosome maturation protein SBDS: sbds