Protein
2-methylisoborneol synthase
Organism
Streptomyces ambofaciens (strain ATCC 23877 / 3486 / DSM 40053 / JCM 4204 / NBRC 12836 / NRRL B-2516)
Function
Catalyzes the cyclization of 2-methylgeranyl diphosphate (2-MeGPP) to 2-methylisoborneol (2-MIB), which likely involves the intermediacy of 2-methyllinalyl diphosphate.
Similarity
Belongs to the terpene synthase family. 2-methylisoborneol synthase subfamily.
Sequence
MPDSGPLGPHSPDHRPTPATTVPDAPASKPPDVAVTPTASEFLAALHPPVPIPSPSPPSGSASAAADTPDATTVGSALQRILRGPTGPGTAALALSVRHDPPSLPGSPAPAEPAAGRAVPGLYHHPVPEPDPARVEEVSRRIKRWAEDEVQLYPEDWEGEFDGFSVGRYMVACHPDAPTVDHLMLATRLMVAENAVDDCYCEDHGGSPVGLGGRLLLAHTAIDPFHTTAEYAPPWRESLTSDAPRRAYRSAMDYFVRAATPSQADRYRHDMARLHLGYLAEAAWAQTDHVPEVWEYLAMRQFNNFRPCPTITDTVGGYELPADLHARPDMQRVIALAGNATTIVNDLYSYTKELDSPGRHLNLPVVIAERERLSERDAYLKAVEVHNELQHAFEAAAAELAKACPLPTVLRFLKGVAAWVDGNHDWHRTNTYRYSLPDFW