Protein
2-methylisoborneol synthase
Organism
Saccharopolyspora erythraea (strain ATCC 11635 / DSM 40517 / JCM 4748 / NBRC 13426 / NCIMB 8594 / NRRL 2338)
Function
Catalyzes the cyclization of 2-methylgeranyl diphosphate (2-MeGPP) to 2-methylisoborneol (2-MIB), which likely involves the intermediacy of 2-methyllinalyl diphosphate.
Similarity
Belongs to the terpene synthase family. 2-methylisoborneol synthase subfamily.
Sequence
MIELIGHETPVPSQQQHTGGVRGTSACTPPGVGERTTVLYCPPPPPERPEVAAEINRRVVVWMQGLGLGGEDNVAGVYKHDPGRGITLCHPGSQDVERMTAAGKMIVAETAVDDYFCETNSRRDANDQTIGPNLSLAQSAIDAPRLTPDLQALWNKCRDDHPVLRAQHEAFGDLERISSPAQAQRVRHDIAQLYLGYNAENGWRLLNRLPPVWQYLANRQMNSFRPCLNLTDALDGYELAPQLYAHPLVQDCTARATLIATLYNDLASCEREIREHGLPFNLPAVIAAEERIALDEAFVRACEIHNELIQALEEATGHAASALADPALSRYLTGLWSWLAGSRHWHFTTARHRA