Rf1

Gene

RF1

Protein

DNA polymerase

Organism

Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37)

Length

995 amino acids

Similarity

Belongs to the DNA polymerase type-B family.

Mass

116.346 kDa

Sequence

MNYIINLKMDYKDKALNDLRNVYADFDSLPLDFRQILIKDRATLLQKEDVEKKILERQEDAKKYAEYLKQSEIPERISLPNIKRHKGVSISFEETSEDMVLEPRPFIFDGLNIRCFRRETIFSLKNKILNMVKESSSFKNVSRQSVSFMYFKIFNKGKVIASTKSVNIYEDKIDERLEDLCNNFDDVLKKIIDVTYGYESLFVSETYSYVIFYAKSIYFPQPRCVNNWGNNIPNILTFDSFKLFTANKNNVSCIKQCSRFLWQKDFNTLEEMIEYKNGNICIVTPQLHINDVRDIKSFNDIRLYSESPIKTFSVIDNTITYLFYFKEHLGVIFNITKSRHDRRVTKFSPLSKFSDVKNITVCFDIESYFDPEKESNQVNIPFICCASIIYNKVIGNIVDFEGRDCVAQMIEYVVDICGELNISSVELIAHNGGGYDFHYILSSMYNPAAIKNILIRNNSFISFNFAHDGVKFSVKDSYSFLLCSLANASKAFLNEETFKKTDFPHHDLKTADDLYKVYKEWSSVNTEINHVVEKEKLLITSEHIVNFTKNDKSKTLIEWSKDYCRNDVLVLSKVWLEFKNAVEDIFNCELVDQTMTLAGLSYKLFQANMPFDVELRHPNKEDYFNMREALIGGRCISVNGIYKDVLCLDVKSLYPASMAFYDQPYGSFKRVSSRPKDELGIYYVRVTPNRNNKSNFFPIRSHNKITYNNFEESTYIAWYTNVDIDIGLSEGHNIEYIPFDSYGNIGYSWSKKGKIFEKYIKDVLYKLKIKYEKQNNKVKRNVIKIIMNSLWGKFAQKWVNFEYFIKSEDDIDFESEEAYKIWDTDFMLIKKIKESTYSSKPIQNGVFTLSWARYHMKSIWDAGAKEGAECIYSDTDSIFVHKEHFKKNAKFMLNGLKVPIIGSEVGQLELECEFDKLLCAGKKQYMGFYTYFQDGKPCIKEKKRFKGIPSNYIIPELYAHLLSGADKEAKIQFLKFRREWGSVKGYIENKTVKAT

Protein

DNA polymerase: RF1

Gene

Rf1

Protein

Protein Rf1, mitochondrial

Organism

Oryza sativa subsp. indica

Length

791 amino acids

Function

Reduces the expression of the cytoplasmic male sterility (CMS)-associated mitochondrial gene ORF79, encoding a cytotoxic peptide. Can restore male fertility by blocking ORF79 production via endonucleolytic cleavage of dicistronic ATP6/ORF79 mRNA. Promotes the editing of ATP6 mRNAs independently of its cleavage function.

Mass

87.614 kDa

Sequence

MARRAASRAVGALRSDGSIQGRGGRAGGSGAEDARHVFDELLRRGRGASIYGLNRALADVARDSPAAAVSRYNRMARAGADEVTPDLCTYGILIGCCCRAGRLDLGFAALGNVIKKGFRVDAIAFTPLLKGLCADKRTSDAMDIVLRRMTELGCIPNVFSYNILLKGLCDENRSQEALELLHMMADDRGGGSPPDVVSYTTVINGFFKEGDSDKAYSTYHEMLDRGILPDVVTYNSIIAALCKAQAMDKAMEVLNTMVKNGVMPDCMTYNSILHGYCSSGQPKEAIGFLKKMRSDGVEPDVVTYSLLMDYLCKNGRCMEARKIFDSMTKRGLKPEITTYGTLLQGYATKGALVEMHGLLDLMVRNGIHPDHYVFSILICAYAKQGKVDQAMLVFSKMRQQGLNPNAVTYGAVIGILCKSGRVEDAMLYFEQMIDEGLSPGNIVYNSLIHGLCTCNKWERAEELILEMLDRGICLNTIFFNSIIDSHCKEGRVIESEKLFELMVRIGVKPNVITYNTLINGYCLAGKMDEAMKLLSGMVSVGLKPNTVTYSTLINGYCKISRMEDALVLFKEMESSGVSPDIITYNIILQGLFQTRRTAAAKELYVRITESGTQIELSTYNIILHGLCKNKLTDDALQMFQNLCLMDLKLEARTFNIMIDALLKVGRNDEAKDLFVAFSSNGLVPNYWTYRLMAENIIGQGLLEELDQLFLSMEDNGCTVDSGMLNFIVRELLQRGEITRAGTYLSMIDEKHFSLEASTASLFIDLLSGGKYQEYYRFLPEKYKSFIESLSC

Protein

Protein Rf1, mitochondrial: Rf1