Protein
4-hydroxy-2-oxovalerate aldolase
Organism
Cupriavidus necator (strain JMP 134 / LMG 1197)
Function
Catalyzes the retro-aldol cleavage of 4-hydroxy-2-oxopentanoate to pyruvate and acetaldehyde. Is involved in the meta-cleavage pathway for the degradation of aromatic compounds.
Similarity
Belongs to the 4-hydroxy-2-oxovalerate aldolase family.
Sequence
MPFNPGKKLYISDVTLRDGSHAIRHQYSIQNVKDIARALDKARVDSIEVAHGDGLQGSSFNYGFGAHTDLEWIEAVAGEISHAQIATLLLPGIGTIHDLDNAYKAGARIVRVATHCTEADVSRQHIERARELGMDTVGFLMMSHMTTPENLAVEAKKMESYGATTIYVVDSGGALSMDDVRARFRALKAVLDPSTTTGMHAHHNLSLGVANSIVAVEEGCDRIDASLAGMGAGAGNAPLEVFIAAADRMGWDHGTDLYTLMDAADDIVRPLQDRPVRVDRETLALGYAGVYSSFLRHSEVAANKYGIKTVDILVELGKRRMVGGQEDMIVDVALDLLNKA