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RVB2

Gene
RVB2
Protein
RuvB-like helicase 2
Organism
Candida albicans (strain SC5314 / ATCC MYA-2876)
Length
498 amino acids
Function
DNA helicase which participates in several chromatin remodeling complexes, including the SWR1 and the INO80 complexes. The SWR1 complex mediates the ATP-dependent exchange of histone H2A for the H2A variant HZT1 leading to transcriptional regulation of selected genes by chromatin remodeling. The INO80 complex remodels chromatin by shifting nucleosomes and is involved in DNA repair. Also involved in pre-rRNA processing (By similarity).
Similarity
Belongs to the RuvB family.
Mass
54.549 kDa
Sequence
MATNTITTTKVTTTTTDVTGLSLIAAHSHISGLGLDDNLQPKENAQGMVGQLSARKAAGVILKMVEAGKIAGRAVLIAGPPSTGKTAIAMGLSQSLGNQVPFTALAASEVFSLELSKTEALTQAFRKSIGIKIKEETEIIEGEVVEIQIDRTITGGHKQGKLTIKTTDMETIYELGNKMIEGLTKEKVLAGDVISIDKASGKITKLGRSFTRARDYDAMGPETKFVQCPEGELQKRKEVVHTISLHEIDVINSRQQGFLALFSGDTGEIRPEVRDQINTKVAEWKEEGKAEIVPGVLFIDEVHMLDIECFSFINRALEDEFSPIVIMATNRGVSRIRGTDYKSPHGMPMDLLDRSITIHTTSYTADEIRTILSIRATEEEVELSGDALALLTKIGQETSLRYAANLISVSQQIALKKKNNTVDLQDIKRAYMLFLDSDRSVQYLEENADQYIDDYGRVTIGQESTDGSTQPQAKQQEVAQPEATQPQSQPEDDKMETD
Protein
RuvB-like helicase 2: RVB2

Gene
RVB2
Protein
RuvB-like helicase 2
Organism
Debaryomyces hansenii (strain ATCC 36239 / CBS 767 / JCM 1990 / NBRC 0083 / IGC 2968)
Length
480 amino acids
Function
DNA helicase which participates in several chromatin remodeling complexes, including the SWR1 and the INO80 complexes. The SWR1 complex mediates the ATP-dependent exchange of histone H2A for the H2A variant HZT1 leading to transcriptional regulation of selected genes by chromatin remodeling. The INO80 complex remodels chromatin by shifting nucleosomes and is involved in DNA repair. Also involved in pre-rRNA processing (By similarity).
Similarity
Belongs to the RuvB family.
Mass
52.396 kDa
Sequence
MSANTISTKVQSKDLNGLSLIAAHSHISGLGLDDNLQPKESGQGMVGQLKARKAAGVILKMIQAGKIAGRAVLVAGPPSTGKTAIAMGLSQNLGSEVPFTAIAGSEIFSLELSKTESLTQAFRKSIGIKIKEETEMIEGEVVEIQIDRSITGGHKQGKLTIKTTDMETIYELGNKMIEGLTKEKVLAGDVISIDKASGKITKLGKSFTRARDYDAMGPETKFVQCPEGELQKRKEVVHTVSLHEIDVINSRQQGFLALFSGDTGEIRSEVRDQINTKVAEWKEEGKAEIVPGVLFIDEVHMLDIECFSFINRALEDDFAPIVIMATNRGISKTRGTNYKSPHGLPMDLLDRSIIIHTAPYNADEIRTILLIRATEEEVELTGDALALLTKIGQETSLRYASNLISVSQQIALKRRSNSVDLPDIKRSYMLFLDSDRSVQYLEEFSTQFIDDSGNVTFGTNDASVKQTKGAANGEDKMETD
Protein
RuvB-like helicase 2: RVB2

Gene
RVB2
Protein
RuvB-like helicase 2
Organism
Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65)
Length
476 amino acids
Function
DNA helicase which participates in several chromatin remodeling complexes, including the SWR1 and the INO80 complexes. The SWR1 complex mediates the ATP-dependent exchange of histone H2A for the H2A variant HZT1 leading to transcriptional regulation of selected genes by chromatin remodeling. The INO80 complex remodels chromatin by shifting nucleosomes and is involved in DNA repair. Also involved in pre-rRNA processing (By similarity).
Similarity
Belongs to the RuvB family.
Mass
52.03 kDa
Sequence
MSIQTSDPNDPNGSLKSLSLIAAHSHITGLGLDDNLQPRASSEGMVGQLQARRAAGVILRMIQNGSIAGRAILVAGPPSTGKTALAMGLSQSLGKDVPFTAITGSEIFSLELSKTEALTQAFRKSIGIKIKEETELIEGEVVEIQIDRSITGGHKQGKLTIKTTDMETIYELGNKMIDGLTKEKVLAGDVISIDKASGKITKLGRSFARSRDYDAMGYDTKFVQCPEGELQKRKTVVHTVSLHEIDVINSRTQGFLALFTGDTGEIRSEVRDQINTKVAEWKEEGKAEIVPGVLFIDEVHMLDIECFSFINRALEDEFAPIIMMATNRGISKTRGTNYKSPHGLPLDLLDRSIIITTSNYNEEEIKTILTIRAQEEEVELSPDALDLLTKTGGETSLRYSSNLISVAQQIALKRKSNTVEVADVKKAYLLFLDSSRSVKFVQENQDQYIDDNGKVIISTSGEMTQPADGEAMDTTE
Protein
RuvB-like helicase 2: RVB2

Gene
RVB2
Protein
RuvB-like helicase 2
Organism
Ustilago maydis (strain 521 / FGSC 9021)
Length
476 amino acids
Function
DNA helicase which participates in several chromatin remodeling complexes, including the SWR1 and the INO80 complexes. The SWR1 complex mediates the ATP-dependent exchange of histone H2A for the H2A variant HZT1 leading to transcriptional regulation of selected genes by chromatin remodeling. The INO80 complex remodels chromatin by shifting nucleosomes and is involved in DNA repair. Also involved in pre-rRNA processing (By similarity).
Similarity
Belongs to the RuvB family.
Mass
52.411 kDa
Sequence
MAQISTTSEHTIQTLERIGAHSHVKGLGLDDQLEPRPSSQGMVGQRAARKAAGLIVKMVQDGRIAGRAILMVGPPSTGKTAIAMGMAQTLGSDVPFTMLSASEVFSLEMSKTEALMQAFRRSIGVRIREEAEVVEGEVVEIQIDRSLTGATKTGKLTIKTTDMETIYELGNKMIDSLQKEKVTAGDVIAIDKASGRITKLGRSFTRARDYDAMGSDTKFVQCPEGELQRRKDVVHTVSLHEIDVINSRTQGFLALFSGDTGEIKPELRDQINIKVGEWREEGKAEIVPGVLFIDEVHMLDIECFSFLNRALESELAPLVIMASNRGICRIRGTRFRSPHGIPIDLLDRVLIISTKPYELADLKQILTIRAAEEEVSLKPEALEVLTRMASETSLRYAINLITTANLAAKRRKADEVEVADVRRVYNLFVDEKRSVQYLKEHAEQFMNESDEYGDIDGLNSGAPIIGRQASAGAVQA
Protein
RuvB-like helicase 2: RVB2

Gene
RVB2
Protein
RuvB-like helicase 2
Organism
Gibberella zeae (strain PH-1 / ATCC MYA-4620 / FGSC 9075 / NRRL 31084)
Length
473 amino acids
Function
DNA helicase which participates in several chromatin remodeling complexes, including the SWR1 and the INO80 complexes. The SWR1 complex mediates the ATP-dependent exchange of histone H2A for the H2A variant HZT1 leading to transcriptional regulation of selected genes by chromatin remodeling. The INO80 complex remodels chromatin by shifting nucleosomes and is involved in DNA repair. Also involved in pre-rRNA processing (By similarity).
Similarity
Belongs to the RuvB family.
Mass
51.608 kDa
Sequence
MAAPVMTVSDSKDLRGLNLIAAHSHIRGLGVDATTLEPRASSQGLVGQEKARKAAAVMLQMIKEGKIAGRAVLIAGPPSTGKTAIAMGMAQSLGPDVPFTTLASSEIFSLEMSKTEALTQAFRKSIGVRIKEESEIMEGEVVEIQIDRSVTGSAKQGKLTIKTTDMEAVYDMGSKMIDAMTKERVMAGDIISIDKSSGKITKLGRSYARSRDYDAMGVDTKFLQCPDGELQKRKEVVHTVTLHEIDVINSRTQGFLALFSGDTGEIRSEIRDQINTKVGEWKEEGKAEIVPGVLFIDEVHMLDIECFSYINRALEDDLAPVVIMASNRGNSRIRGTDYRSPHGLPLDFLDRVAIINTHSYTPEEIKQIISIRAQEEEVDVHPDALALLTKIGQEAGLRYASNLITTSQLVSAKRKAKQVEVSDVQRSFQLFYDPARSIKFVAESEKRLIGNTGAVDFSVGAAVSNGEEKMDLS
Protein
RuvB-like helicase 2: RVB2

Gene
RVB2
Protein
RuvB-like protein 2
Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
Length
471 amino acids
Function
DNA helicase which participates in several chromatin remodeling complexes, including the SWR1 and the INO80 complexes. The SWR1 complex mediates the ATP-dependent exchange of histone H2A for the H2A variant HZT1 leading to transcriptional regulation of selected genes by chromatin remodeling. The INO80 complex remodels chromatin by shifting nucleosomes. Its ability to induce transcription of some phosphate-responsive genes is modulated by inositol polyphosphates. The INO80 complex is involved in DNA repair by associating to 'Ser-129' phosphorylated H2A histones as a response to DNA damage. During transcription may recruit SPT15/TBP to the TATA-boxes of involved genes. Required for box C/D and box H/ACA snoRNA accumulation and involved in pre-rRNA processing.
Similarity
Belongs to the RuvB family.
Mass
51.612 kDa
Sequence
MSIQTSDPNETSDLKSLSLIAAHSHITGLGLDENLQPRPTSEGMVGQLQARRAAGVILKMVQNGTIAGRAVLVAGPPSTGKTALAMGVSQSLGKDVPFTAIAGSEIFSLELSKTEALTQAFRKSIGIKIKEETELIEGEVVEIQIDRSITGGHKQGKLTIKTTDMETIYELGNKMIDGLTKEKVLAGDVISIDKASGKITKLGRSFARSRDYDAMGADTRFVQCPEGELQKRKTVVHTVSLHEIDVINSRTQGFLALFTGDTGEIRSEVRDQINTKVAEWKEEGKAEIVPGVLFIDEVHMLDIECFSFINRALEDEFAPIVMMATNRGVSKTRGTNYKSPHGLPLDLLDRSIIITTKSYNEQEIKTILSIRAQEEEVELSSDALDLLTKTGVETSLRYSSNLISVAQQIAMKRKNNTVEVEDVKRAYLLFLDSARSVKYVQENESQYIDDQGNVQISIAKSADPDAMDTTE
Protein
RuvB-like protein 2: RVB2

Gene
RVB2
Protein
RuvB-like helicase 2
Organism
Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)
Length
469 amino acids
Function
DNA helicase which participates in several chromatin remodeling complexes, including the SWR1 and the INO80 complexes. The SWR1 complex mediates the ATP-dependent exchange of histone H2A for the H2A variant HZT1 leading to transcriptional regulation of selected genes by chromatin remodeling. The INO80 complex remodels chromatin by shifting nucleosomes and is involved in DNA repair. Also involved in pre-rRNA processing (By similarity).
Similarity
Belongs to the RuvB family.
Mass
51.511 kDa
Sequence
MSIQTQEAHDMSLKSLSLIATHSHIVGLGLDENLQPKPSSQGMVGQLQARRAAGVILKMVQNGTIAGRAVLVAGPPSTGKTALAMGLSQSLGADVPFTAMAGSEIFSLELSKTEALTQAFRKSIGVKIKEDTELIEGEVVEIQIDRSITGGHKQGKLTIKTTDMETIYELGNKMIDGLTKEKVLAGDVISIDKACGKITKLGRSFARSRDYDAMGPDTKFVQCPEGELQKRKSVVHTVSLHEIDVINSRTQGFLALFTGDTGEIRSEVRDQINTKVAEWKEEGKAEIVPGVLFIDEVHMLDIECFSFINRALEDEFAPIVIMATNRGISKTRGTNYKSPHGLPLDLLDRSIIITTQNYSEQEIKTILSIRSQEEEVELTEDALDLLTKIGGETSLRYSSNLIAVSQQIAQKRKSSSVDVQDVKRAYLLFLDSTRSAKYLQEYESRYIDDHGRVDISTTGRNADAMDTNE
Protein
RuvB-like helicase 2: RVB2

Gene
rvb2
Protein
RuvB-like helicase 2
Organism
Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100)
Length
469 amino acids
Function
DNA helicase which participates in several chromatin remodeling complexes, including the SWR1 and the INO80 complexes. The SWR1 complex mediates the ATP-dependent exchange of histone H2A for the H2A variant HZT1 leading to transcriptional regulation of selected genes by chromatin remodeling. The INO80 complex remodels chromatin by shifting nucleosomes and is involved in DNA repair. Also involved in pre-rRNA processing (By similarity).
Similarity
Belongs to the RuvB family.
Mass
51.347 kDa
Sequence
MAVPISTVAETKELRGLNLIAAHSHIRGLGVDADSLQPRTSSQGLVGQEKARKAAAVILQMVKEGKIAGRAVLIAGPPSTGKTAIAMGMAQSLGSDVPFTMLAASEIFSMEMSKTEALTQAFRKSIGVRIKEESEIIEGEVVEIQVDRSVTGGNKQGKLTIKTTDMETIYDMGTKMIDSMTKERVMAGDVISIDKSSGKITKLGRSYARSRDYDAMGADTKFVQCPEGELQVRKEIVHTVSLHEIDVINSRTQGFLALFSGDTGEIRSEVRDQINTKVAEWKEEGKAEIIPGVLFIDEVHMLDIECFSYINRALEAELAPIVIMASNRGQARIRGTTYTSPHGLPLDFLDRVVIVSTQPYSGDEIRQILAIRAQEEEIDLSPDALALLTKIGQESNLRYASNIITTSHLLSQKRKAKEVSIDDVQRSYRLFYDPARSVKFVNAYEQRFIGDQGAVNFSAPANGDAMEIS
Protein
RuvB-like helicase 2: rvb2

Gene
rvb2
Protein
RuvB-like helicase 2
Organism
Dictyostelium discoideum
Length
469 amino acids
Function
Proposed core component of the chromatin remodeling Ino80 complex which is involved in transcriptional regulation, DNA replication and probably DNA repair.
Similarity
Belongs to the RuvB family.
Mass
51.971 kDa
Sequence
MSIPKISQVKDLTRIERIGAHSHIRGLGIDDSLEPREISQGMVGQVGARKAAGLILQMIKEGKIAGRAILIGGEPGTGKTAIAMGMAQSLGEKTPFTAIAASEIFSLEMSKTEALTQAFRRSIGVRIKEETEVICGEVVDIQIDRPATGSGAKVGKLTLKTTSMDALYDLGAKMIDSLTKEKVQNGDIIRIDKGTGKITKLGRSLSRVRDHEISGSKVNFIECPEGEIQQRRTETHTVSLHEIDVINSRAQGFFALFAGDIGEIKSEVREQINQKVAEWKEEGKAEIVPGVLFIDEVHMLDIECFSYLNRALEDDMSPILIIATNRGNTTIRGTDYKAPHGIPLDLLDRLLIINTQPYTEKDIYKILKIRCEEEDVDIQEDALQLLTKIGVETSLRYAIHLITSSSLVSVKRKGTDVSVDDIKKVYDLFVDVKRSTKYLKDYQDEYLYNSQPETTATKTNEEQQTMQTA
Protein
RuvB-like helicase 2: rvb2

Gene
rvb2
Protein
RuvB-like helicase 2
Organism
Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139)
Length
468 amino acids
Function
DNA helicase which participates in several chromatin remodeling complexes, including the SWR1 and the INO80 complexes. The SWR1 complex mediates the ATP-dependent exchange of histone H2A for the H2A variant HZT1 leading to transcriptional regulation of selected genes by chromatin remodeling. The INO80 complex remodels chromatin by shifting nucleosomes and is involved in DNA repair. Also involved in pre-rRNA processing (By similarity).
Similarity
Belongs to the RuvB family.
Mass
51.46 kDa
Sequence
MAAPISTVAESKELRGLNLIAAHSHIRGLGVDVDSLQPRPASQGLVGQEKARKAAAVILQMVKEGKIAGRAVLIAGPPSTGKTAIAMGMAQSLGPDVPFTMLAASEIFSMEMSKTEALTQAFRKSIGVRIKEESEIIEGEVVEIQIDRSVTGGNKQGKLTIKTTDMETIYDMGTKMIDSMTKERVMAGDIISIDKSSGKITKLGRSYARSRDYDAMGADVKFVQCPEGELQVRKEIVHTVSLHEIDVINSRSQGFLALFSGDTGEIRSEVRDQINVKVAEWKEEGKAEIIPGVLFIDEVHMLDIECYSYINRALEAELAPIVIMASNRGHSRIRGTTYNSPHGLPLDFLDRVVIVSTQHYSADEIRQILAIRAQEEEIDLSPDALALLTKIGQESNLRYASNIITTSHLLSQKRKAKEVSVDDVQRSYRLFYDPARSVKFVNQYEQRFIGDQGNVNFTASNGDAMEIS
Protein
RuvB-like helicase 2: rvb2

Gene
RVB2
Protein
RuvB-like helicase 2
Organism
Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37)
Length
467 amino acids
Function
DNA helicase which participates in several chromatin remodeling complexes, including the SWR1 and the INO80 complexes. The SWR1 complex mediates the ATP-dependent exchange of histone H2A for the H2A variant HZT1 leading to transcriptional regulation of selected genes by chromatin remodeling. The INO80 complex remodels chromatin by shifting nucleosomes and is involved in DNA repair. Also involved in pre-rRNA processing (By similarity).
Similarity
Belongs to the RuvB family.
Mass
51.126 kDa
Sequence
MSIQTQDSQETLKSLSLIAAHSHISGLGLDENLQPKPSSQGMVGQLQARRAAGVILKMVQNGSIAGRAVLVAGPPSTGKTALAMGLSQSLGKDVPFTAIAGSEIFSLELSKTEALTQAFRKSIGIKIKEETELIEGEVVEIQIDRSITGGHKQGKLTIKTTDMETIYELGNKMIEGLTKEKVLAGDVISIDKASGKITKLGRSFARSRDYDAMGADTKFVQCPEGELQKRKTVVHTVSLHEIDVINSRTQGFLALFTGDTGEIRSEVRDQINTKVAEWKEEGKAEIVPGVLFIDEVHMLDIECFSFINRALEDEFAPIVIMATNRGISKTRGTNYKSPHGLPLDLLDRSIIITTKNYDASEIKTILTIRSTEEEVELSPEALDLLTNIGSETSLRYSSNLISVSQQIAQKRKSNTVEVKDVERAYLLFLDSARSVKFVQEFESQYIDDKGQVNISIGKDEDAMDTTA
Protein
RuvB-like helicase 2: RVB2

Gene
RVB2
Protein
RuvB-like helicase 2
Organism
Yarrowia lipolytica (strain CLIB 122 / E 150)
Length
466 amino acids
Function
DNA helicase which participates in several chromatin remodeling complexes, including the SWR1 and the INO80 complexes. The SWR1 complex mediates the ATP-dependent exchange of histone H2A for the H2A variant HZT1 leading to transcriptional regulation of selected genes by chromatin remodeling. The INO80 complex remodels chromatin by shifting nucleosomes and is involved in DNA repair. Also involved in pre-rRNA processing (By similarity).
Similarity
Belongs to the RuvB family.
Mass
50.526 kDa
Sequence
MSIATVAQAKDVRGLNLVAAHSHITGLGLEPNSLTPKENAQGMVGQVKARRAAAVVLQMIKDGKIAGRSVLLAGPPSTGKTAIAMGISQSLGSDVPFTSLAGSEIYSLELSKTEALNQAFRKSIGVRIKETTDIIEGEVVEIQIDRSLSGGHKQGKLTIKTTDMETIYDLGHKMIDSLSNEKVTAGDVISIDKASGRITKLGRSFARARDYDALGADTKFVQCPEGELQQRKEVIHTVSLHEIDVINSRSQGFLALFSGDTGEIRPEVREQINTKVAEWKEEGKAEIVPGVLFIDEVHMLDMECFSFINRALEDDMAPIVIMATNRGQSTTRGTDYKSPHGLPVDLLDRVIIIPTSPYSPDEVKQILQIRANEEEVELSPEALEILTSIGADTSLRYGSNLISVSHMLAQKRKASSVGLEDVKRAYSLFLDTARSVQFLSSSNNYVGEDGTAKLGEREKDAMDTSA
Protein
RuvB-like helicase 2: RVB2

Gene
rvb2
Protein
RuvB-like helicase 2
Organism
Schizosaccharomyces pombe (strain 972 / ATCC 24843)
Length
465 amino acids
Function
DNA helicase which participates in several chromatin remodeling complexes, including the SWR1 and the INO80 complexes. The SWR1 complex mediates the ATP-dependent exchange of histone H2A for the H2A variant HZT1 leading to transcriptional regulation of selected genes by chromatin remodeling. The INO80 complex remodels chromatin by shifting nucleosomes and is involved in DNA repair. Also involved in pre-rRNA processing (By similarity).
Similarity
Belongs to the RuvB family.
Mass
51.562 kDa
Sequence
MSISVTSHNDVSKLERIGAHSHIKGIGLNDNLEPKESSQGMVGQVKARRAAGVILKMIQEGRIAGRAILMAGPPSTGKTAIAMGMAQSLGSDTPFVTLSASEVYSLEMSKTEALLQALRKSIGVRIKEETEIIEGEVVEVQIDRSITGGNKQGKLTIRSTDMETVYDLGTKMIDSLTKEKVLAGDVISIDKSVGRVTKLGRSFSRARDYDAMGADTRFVQCPQGEIQKRKEVVHTVSLHDIDVINSRTQGFLALFSGDTGEIKPEVREQINTKVSEWREEGKAEIVPGVLFVDEVHMLDIECFSFFNRALEDDLAPIVIMASNRGITRIRGTNYRSPHGIPVDLLDRMLIISTLPYSHEEVKEILKIRCQEEDVDMEPSALDYLSTIGQETSLRYALLLISSSNQVALKRKSATIEESDIRRVYELFLDQKRSVEYLEEYGKNYITENEWSASGAQDNAVAMQED
Protein
RuvB-like helicase 2: rvb2

Gene
RVB2
Protein
RuvB-like helicase 2
Organism
Cryptococcus neoformans var. neoformans serotype D (strain B-3501A)
Length
463 amino acids
Function
DNA helicase which participates in several chromatin remodeling complexes, including the SWR1 and the INO80 complexes. The SWR1 complex mediates the ATP-dependent exchange of histone H2A for the H2A variant HZT1 leading to transcriptional regulation of selected genes by chromatin remodeling. The INO80 complex remodels chromatin by shifting nucleosomes and is involved in DNA repair. Also involved in pre-rRNA processing (By similarity).
Similarity
Belongs to the RuvB family.
Mass
50.89 kDa
Sequence
MAANISLQPTSMRDVTKMERIGVHSHIHGLGLDSNLEPRASSQGMIGQGKARKAAGVILKMVQEGRIAGRAILMAGPPSTGKTALAMAMTQTLGSDVPFVMLTASEVFSLEISKTESLTQAFRRAIGVRIKEETELIEGEVVEIQVDRSVTGATKTGRLTLKTTDMETVYDLGSKMIDQLQKEKVLAGDVVSIDKASGRISKLGRSFGRAKDYDAMGADTRFVACPDGELQTRKEVVHTVSLHEIDVINSRTQGFLALFAGDTGEIKPELRAQINGKVAEWREEGKAEIVPGVLFIDEVHMLDIECFSFLNRAMENELAPLVVMASNRGITRIRGTKYKSPHGIPADLLDRMLIISTNRYEEDEMREIVKIRAEEEDVRLSPAALDLLATMGIQTSLRYSLNLIAPSSLLAQRRKSPQTDVEDVRMAYKYFCDVERSAQYAKETSGMMFGETEEINGGMEVDA
Protein
RuvB-like helicase 2: RVB2

Gene
RVB2
Protein
RuvB-like helicase 2
Organism
Cryptococcus neoformans var. neoformans serotype D (strain JEC21 / ATCC MYA-565)
Length
463 amino acids
Function
DNA helicase which participates in several chromatin remodeling complexes, including the SWR1 and the INO80 complexes. The SWR1 complex mediates the ATP-dependent exchange of histone H2A for the H2A variant HZT1 leading to transcriptional regulation of selected genes by chromatin remodeling. The INO80 complex remodels chromatin by shifting nucleosomes and is involved in DNA repair. Also involved in pre-rRNA processing (By similarity).
Similarity
Belongs to the RuvB family.
Mass
50.89 kDa
Sequence
MAANISLQPTSMRDVTKMERIGVHSHIHGLGLDSNLEPRASSQGMIGQGKARKAAGVILKMVQEGRIAGRAILMAGPPSTGKTALAMAMTQTLGSDVPFVMLTASEVFSLEISKTESLTQAFRRAIGVRIKEETELIEGEVVEIQVDRSVTGATKTGRLTLKTTDMETVYDLGSKMIDQLQKEKVLAGDVVSIDKASGRISKLGRSFGRAKDYDAMGADTRFVACPDGELQTRKEVVHTVSLHEIDVINSRTQGFLALFAGDTGEIKPELRAQINGKVAEWREEGKAEIVPGVLFIDEVHMLDIECFSFLNRAMENELAPLVVMASNRGITRIRGTKYKSPHGIPADLLDRMLIISTNRYEEDEMREIVKIRAEEEDVRLSPAALDLLATMGIQTSLRYSLNLIAPSSLLAQRRKSPQTDVEDVRMAYKYFCDVERSAQYAKETSGMMFGETEEINGGMEVDA
Protein
RuvB-like helicase 2: RVB2

Gene
RVB2
Protein
RuvB-like helicase 2
Organism
Encephalitozoon cuniculi (strain GB-M1)
Length
418 amino acids
Function
DNA helicase which participates in several chromatin remodeling complexes, including the SWR1 and the INO80 complexes. The SWR1 complex mediates the ATP-dependent exchange of histone H2A for the H2A variant HZT1 leading to transcriptional regulation of selected genes by chromatin remodeling. The INO80 complex remodels chromatin by shifting nucleosomes and is involved in DNA repair. Also involved in pre-rRNA processing (By similarity).
Similarity
Belongs to the RuvB family.
Mass
46.375 kDa
Sequence
MEIRDVETVNRINLHSHIAGLGCDGDEVEYDKDGLVGQIKARKAMAVIRKMVESNKGGKVVLIKGDRGSGKTALAIGLSKSLGGVHFNSISGTEIYSLEMSKSEAITQALRKSVGLRIKESVKVIEGEVVSLSGRRIVLKTVDMESSFEIGEKMRGELDKEKVSAGDVIRIVRERGRVYKIGTSMVKRSDVVGTDTRFVPCPEGELIRITEETQEISLHDIDVVNSKAEGYLALFSGETGEIRAETRDEVNKKVWGWINEGKAEIVRGVLFIDEVHMLDIESFAFLNKAVEEDFCPVILVSTNKGECIVRGTDEPSPYGIPRDFIDRALIISMEKHCRRDLEAILRHRILEEDILIDDDAVDRLVSISEASGLRYSMNLLTISSMRASRRNGRVALGDVERAFELFLDEARGTESFNG
Protein
RuvB-like helicase 2: RVB2