RUG3

Gene

RUG3

Protein

RCC1 domain-containing protein RUG3, mitochondrial

Organism

Arabidopsis thaliana

Length

445 amino acids

Function

Regulates DNA damage response (DDR) synergistically with ATM (PubMed:28262819). Together with ATM, involved in the splicing of the ND2/NAD2 mRNA (PubMed:21623974, PubMed:28262819). Required for the accumulation of mitochondrial respiratory chain complex I (PubMed:21623974). Negative regulator of plant responses to abscisic acid (ABA) (PubMed:28613105). May have a pivotal role in vegetative growth and the phase transition from vegetative to reproductive growth (PubMed:28262819).

Mass

47.331 kDa

Sequence

MAALSHRLRSFTRRFSSTRTTQRSGGGANTKVPILYTSPDIDSDPVTLQLFSWGRGASGQLGGGIEEIRMYPSPVANLLFRSDQSFSLAQTPGRIDADSSSFRIGISCGLFHSGLTIDGDLWIWGKGDGGRLGFGQENSVFVPNLNPLFEEHSIRCIALGGLHSVALTHQGDVFTWGYGGFGALGHKVYTRELVPRRVDDSWDCKISAIATSGTHTAAITESGELYMWGREEGDGRLGLGPGRGPNEGGGLSVPSKVKALTVPVASVSCGGFFTMALTKEGQLWNWGANSNYELGRGDNLGGWEPMPVPSLEGVRITQIACGGYHSLALTEEGKVLSWGHGGHGQLGSSSLRNQKVPTEIEALADKKIVFIASGGSSSAAITDGGELWMWGNAKDFQLGVPGLPEIQTTPVEVNFLTEEDECQPHKVISISIGASHALCLVSRSP

Protein

RCC1 domain-containing protein RUG3, mitochondrial: RUG3