RTA1

Gene

RTA1

Protein

Lipid-translocating exporter-like protein RTA1

Organism

Leptosphaeria maculans (strain JN3 / isolate v23.1.3 / race Av1-4-5-6-7-8)

Length

521 amino acids

Function

Lipid-translocating exporter-like protein; part of the gene cluster that mediates the biosynthesis of phomenoic acid, a long chain aliphatic carboxylic acid that does not appear to be essential for pathogenicity but may play a role in allowing to outcompete other fungi in the environmental niche via its antifungal properties.

Similarity

Belongs to the lipid-translocating exporter (LTE) (TC 9.A.26.1) family.

Mass

58.112 kDa

Sequence

MNAYAYTACLGIYGSTPNNEQLVLGSPDQLQRNKPRFRLIVLPHAPAASPFYPPWRSFAPDWEGQGARPMDHFKVGNLRFQLETHRIDEHSTFGKLFGHAPSPSQSCVSFQKKSDRAEPLLLARCSAASWSCIHPPTVLYFVAYQLEYPFAARFSATKISPIQDKMVATSDVPIVGSLYVYAPNKGAPIFFTIAFAISTILHSWQCHRYKAWKLIWLQPACAALFTLGYALREYGAYNYLYDGTEKAPLALFILSQICIYLGPPLLELANYHILGRVFHYVPYAAPFNPGRVTAFFGGLMAIVEGLSGSGVSLTANAKAKESTKKTGHNLLLVALALQVCVIFIFVYLSVLFHRRCIKAKVPAQSKAVKSTLMTLYLSMALIFIRCVFRLVEMATSSTSVDITSMERLMKLSPVLRNEAYFYAFEASLMLINSFLWNVQHPGPHLPGDTHIYLAQDGTEVEGEGDGSEDRPLLLNMANTLMFGLLYRDDKDHTHSQPQELYENPNGNGHKKFRLGNGGRAT

Protein

Lipid-translocating exporter-like protein RTA1: RTA1

Gene

RTA1

Protein

Protein RTA1

Organism

Saccharomyces cerevisiae (strain ATCC 204508 / S288c)

Length

317 amino acids

Function

Involved in 7-aminocholesterol resistance.

Similarity

Belongs to the lipid-translocating exporter (LTE) (TC 9.A.26.1) family.

Mass

35.486 kDa

Sequence

MAKDGFELYRYTPELGASILFTVLFAVSGVAFVILLFHYSVKSKRRVGSLMKSQPVLRYYGTVNLAGAYIPFIFGCFVECVGFAFRCKSSKDTTLLNPYIIQTVFLLVSPTLYAASIYMIFGRMATLLFAENLMIMPARFNTTIFVIGDVGSLLLQAIGGAMMSKVTSASSGSHLVTAGLFIQIAFFGLFIINEVLFIFKMSKKPTNVSVRYGSWKYLNIALLVNSFLILIRSIVRAVEFIQGYDGEIASHEWYLYIFDGLPMFLLVLIFIVAFPLINIFRIHEESIQAQQSARFDGTDYPDVEVTSIEEDLASKSE

Protein

Protein RTA1: RTA1

Gene

RTA1

Protein

Lipid-translocating exporter-like protein RTA1

Organism

Ajellomyces capsulatus

Length

312 amino acids

Function

Lipid-translocating exporter-like protein; part of the gene cluster that mediates the biosynthesis of hydroxamate-containing siderophores that play a critical role in virulence via intracellular iron acquisition during macrophage infection (PubMed:18404210).

Similarity

Belongs to the lipid-translocating exporter (LTE) (TC 9.A.26.1) family.

Mass

34.277 kDa

Sequence

MSPESKKITAHGSTSMPLSRTSKPQKFTIPLTVGAIFSVIGFLQRFFLASGKGDVQSLYTLSTMFILGAGPTYAGADYFICGRLFSFVPSAAPMSPIRVVRTFITFDVLAEVCVWTGAGLLAGAHTDTAARYKIGLNLIRAAMITQAFLFTSFVAILASFHVRVCALRAEWSVTSNGGTGRRFMMVVHSLYASSIFIIIRSAYHIAGHSFRTNEQPFLICEASLMLLNTAMFNVFHPGHILPIDSRVYVGIDGQERANETIEGAFTDSRPLLQKILDPLDVKGLFSRDKKRWHDPTAELEMDINSTLYAALT

Protein

Lipid-translocating exporter-like protein RTA1: RTA1