Protein
Replication protein A 70 kDa DNA-binding subunit E
Organism
Arabidopsis thaliana
Function
Component of the replication protein A complex (RPA) required for DNA recombination, repair and replication. The activity of RPA is mediated by single-stranded DNA binding and protein interactions. Probably involved in repair of double-strand DNA breaks (DSBs) induced by genotoxic stresses (By similarity).
Similarity
Belongs to the replication factor A protein 1 family.
Sequence
MEVSLTAGAIGKIMNGEVTTEADMIPVLQVTDLKQIMAQQDPTRERFRMVLSDGTYLHQGMLGTDLNNLVKEGTLQPGSIVRLTRFVGDVIKGRRIVIVPQLEVLKQISDIIGHPVPGGKHNDQRGADSGIKFNTTEQQGSGIRQVNNIEPGRSNAAISPQVGGTGSSVPASTTPSTRAYSNPSSGNGVTRQDYARDPPTSYPHQPQPPPPMYANRGPVARNEAPPKIIPVNALSPYSGRWTIKARVTNKAALKQYSNPRGEGKVFNFDLLDADGGEIRVTCFNAVADQFYDQIVVGNLYLISRGSLRPAQKNFNHLRNDYEIMLDNASTIKQCYEEDAAIPRHQFHFRTIGDIESMENNCIVDVIGIVSSISPTVTITRKNGTATPKRSLQLKDMSGRSVEVTMWGDFCNAEGQRLQSLCDSGVFPVLAVKAGRISEFNGKTVSTIGSSQLFIDPDFVEAEKLKNWFEREGKSVPCISLSREFSGSGKVDVRKTISQIKDEKLGTSEKPDWITVSATILYLKFDNFCYTACPIMNGDRPCSKKVTDNGDGTWRCEKCDKSVDECDYRYILQLQIQDHTDLTCVTAFQEAGEEIMGISAKDLYYVKNEHKDEEKFEDIIRKVAFTKYNFKLKVKEETFSDEQRVKATVVKVDKLNYSADTRTMLGAMDKLRTRDANSLPINPEGSDYNADVVNTGIGSSGTRDPSSVQRRDFGLHAHQSGQSGNHYSGGGATTSCNVCGNSGHVSAKCPGATKPQEQGQYMGGSYRGTTGSYGGGLPRQHVGSY