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RNF114

Gene
RNF114
Protein
E3 ubiquitin-protein ligase RNF114
Organism
Bos taurus
Length
230 amino acids
Function
E3 ubiquitin-protein ligase promoting the ubiquitination and degradation of the CDK inhibitor CDKN1A and probably also CDKN1B and CDKN1C. These activities stimulate cell cycle's G1-to-S phase transition and suppress cellular senescence. May play a role in spermatogenesis.
Mass
25.669 kDa
Sequence
MAAQAQAPARDGGAQLAGPAAEADPLGRFTCPVCLEVYEKPVQVPCGHVFCSACLQECLKPKKPVCGVCRSALAPGVRAVELERQIESTETSCHGCRKNFFLSKIRAHVATCSKYQNYIMEGVKATTKDASRQPRSVPNRYTFPCPYCPEKNFDQEGLVEHCKLSHSTDTKSVVCPICASMPWGDPNYRSANFIEHLQRRHQFSYDTFVDYDVDEEDMINQVLQRSIIDQ
Protein
E3 ubiquitin-protein ligase RNF114: RNF114

Gene
Rnf114
Protein
E3 ubiquitin-protein ligase RNF114
Organism
Mus musculus
Length
229 amino acids
Function
E3 ubiquitin-protein ligase promoting the ubiquitination and degradation of the CDK inhibitor CDKN1A and probably also CDKN1B and CDKN1C. These activities stimulate cell cycle's G1-to-S phase transition and suppress cellular senescence. May play a role in spermatogenesis.
Mass
25.745 kDa
Sequence
MAAAQPESRDGAAQSAKPASETDPLSRFTCPVCLEVFEKPVQVPCGHVFCSACLQECLKPKKPVCGVCRSALAPGVRAVELERQIESIETSCHGCRKNFILSKIRAHVTSCSKYQNYIMEGVKATTKDASLQPRNIPNRYTFPCPYCPEKNFDQEGLVEHCKLTHSTDTKSVVCPICASMPWGDPSYRSANFMEHIQRRHRFSYDTFVDYDVDEDDMINQVLQRSIIDQ
Protein
E3 ubiquitin-protein ligase RNF114: Rnf114

Gene
Rnf114
Protein
E3 ubiquitin-protein ligase RNF114
Organism
Rattus norvegicus
Length
229 amino acids
Function
E3 ubiquitin-protein ligase promoting the ubiquitination and degradation of the CDK inhibitor CDKN1A and probably also CDKN1B and CDKN1C. These activities stimulate cell cycle's G1-to-S phase transition and suppress cellular senescence. May play a role in spermatogenesis.
Mass
25.664 kDa
Sequence
MAAAQPESRDGAAQSAKPASETDPLSRFTCPVCLEVFEKPVQVPCGHVFCSACLQECLKPKKPVCGVCRSALAPGVRAAELERQIESIETSCHGCRKDFVLSKIRAHVASCSKYQSYIMEGVKATTKDASLQQRNVPNRYTFPCPYCPEKNFDQEGLVEHCKLTHSTDTKSVVCPICASMPWGDPSYRSANFMEHIQRRHRFSYDTFVDYDVDEDDMINQVLQRSIIDQ
Protein
E3 ubiquitin-protein ligase RNF114: Rnf114

Gene
RNF114
Protein
E3 ubiquitin-protein ligase RNF114
Organism
Homo sapiens
Length
228 amino acids
Function
E3 ubiquitin-protein ligase promoting the ubiquitination and degradation of the CDK inhibitor CDKN1A and probably also CDKN1B and CDKN1C. These activities stimulate cell cycle's G1-to-S phase transition and suppress cellular senescence. May play a role in spermatogenesis.
Mass
25.694 kDa
Sequence
MAAQQRDCGGAAQLAGPAAEADPLGRFTCPVCLEVYEKPVQVPCGHVFCSACLQECLKPKKPVCGVCRSALAPGVRAVELERQIESTETSCHGCRKNFFLSKIRSHVATCSKYQNYIMEGVKATIKDASLQPRNVPNRYTFPCPYCPEKNFDQEGLVEHCKLFHSTDTKSVVCPICASMPWGDPNYRSANFREHIQRRHRFSYDTFVDYDVDEEDMMNQVLQRSIIDQ
Protein
E3 ubiquitin-protein ligase RNF114: RNF114

Gene
RNF114
Protein
E3 ubiquitin-protein ligase RNF114
Organism
Pan troglodytes
Length
228 amino acids
Function
E3 ubiquitin-protein ligase promoting the ubiquitination and degradation of the CDK inhibitor CDKN1A and probably also CDKN1B and CDKN1C. These activities stimulate cell cycle's G1-to-S phase transition and suppress cellular senescence. May play a role in spermatogenesis.
Mass
25.708 kDa
Sequence
MAAQQRDCGGAAQLAGPAAEADPLGRFTCPVCLEVYEKPVQVPCGHVFCSACLQECLKPKKPVCGVCRSALAPGVRAVELERQIESTETSCHGCRKKFFLSKIRSHVATCSKYQNYIMEGVKATIKDASLQPRNVPNRYTFPCPYCPEKNFDQEGLVEHCKLFHSTDTKSVVCPICASMPWGDPNYRSANFREHIQRRHRFSYDTFVDYDVDEEDMMNQVLQRSIIDQ
Protein
E3 ubiquitin-protein ligase RNF114: RNF114

Gene
RNF114
Protein
E3 ubiquitin-protein ligase RNF114
Organism
Sus scrofa
Length
228 amino acids
Function
E3 ubiquitin-protein ligase promoting the ubiquitination and degradation of the CDK inhibitor CDKN1A and probably also CDKN1B and CDKN1C. These activities stimulate cell cycle's G1-to-S phase transition and suppress cellular senescence. May play a role in spermatogenesis.
Mass
25.629 kDa
Sequence
MAAQPQDREGGAQLAGPAAEADPLGRFTCPVCLEVYEKPVQVPCGHVFCSACLQECLKPKKPVCGVCRSTLAPGVRAVELERQIESTETSCHGCRKNFFLSKIRAHVATCSKYQNYIMEGVKATTKDASLQPRNVPNRYTFPCPYCPEKNFDQEGLVEHCKLVHSTDTKSVVCPICASMPWGDPNYRSANFIEHIQRRHQFSYDTFVDYDVDEEDMMNQVLQRSLLDQ
Protein
E3 ubiquitin-protein ligase RNF114: RNF114